Genomic diversity of Helicobacter pylori populations from different regions of the human stomach [0.03%]
来自人体胃不同区域的幽门螺旋杆菌群体的基因组多样性
Daniel James Wilkinson,Benjamin Dickins,Karen Robinson et al.
Daniel James Wilkinson et al.
Individuals infected with Helicobacter pylori harbor unique and diverse populations of quasispecies, but diversity between and within different regions of the human stomach and the process of bacterial adaptation to each location are not ye...
The potential role of adherence factors in probiotic function in the gastrointestinal tract of adults and pediatrics: a narrative review of experimental and human studies [0.03%]
益生菌在成人和儿科消化道功能中粘附因素的潜在作用：实验研究与人体研究的叙述性回顾
Frida Gorreja,W Allan Walker
Frida Gorreja
Numerous studies point to the important role of probiotic bacteria in gastrointestinal health. Probiotics act through mechanisms affecting enteric pathogens, epithelial barrier function, immune signaling, and conditioning of indigenous micr...
Facilitating a high-quality dietary pattern induces shared microbial responses linking diet quality, blood pressure, and microbial sterol metabolism in caregiver-child dyads [0.03%]
高质量饮食模式的促进诱导出与照看者和儿童的血压以及微生物固醇代谢有关的共同微生物反应
Emily B Hill,Li Chen,Michael T Bailey et al.
Emily B Hill et al.
Low-resource individuals are at increased risk of obesity and cardiovascular disease (CVD), partially attributable to poor dietary patterns and dysfunctional microbiota. Dietary patterns in childhood play critical roles in physiological dev...
Randomized Controlled Trial
Gut microbes. 2022 Jan-Dec;14(1):2150502. DOI:10.1080/19490976.2022.2150502 2022
Host acid signal controls Salmonella flagella biogenesis through CadC-YdiV axis [0.03%]
宿主酸信号通过CadC-YdiV轴控制沙门氏菌鞭毛生成
Weiwei Wang,Yingying Yue,Min Zhang et al.
Weiwei Wang et al.
Upon entering host cells, Salmonella quickly turns off flagella biogenesis to avoid recognition by the host immune system. However, it is not clear which host signal(s) Salmonella senses to initiate flagellum control. Here, we demonstrate t...
Prebiotic oligofructose protects against high-fat diet-induced obesity by changing the gut microbiota, intestinal mucus production, glycosylation and secretion [0.03%]
益生元寡果糖通过改变肠道微生物群、肠粘液生成、糖基化和分泌来防止高脂饮食引起的肥胖
Paola Paone,Francesco Suriano,Ching Jian et al.
Paola Paone et al.
Obesity is a major risk factor for the development of type 2 diabetes and cardiovascular diseases, and gut microbiota plays a key role in influencing the host energy homeostasis. Moreover, obese mice have a different gut microbiota composit...
Clara Delaroque,Gary D Wu,Charlene Compher et al.
Clara Delaroque et al.
The human gut microbiota is highly heterogenous between individuals and also exhibits considerable day-to-day variation within individuals. We hypothesized that diet contributed to such inter- and/or intra-individual variance. Hence, we inv...
Microbial bile salt hydrolase activity influences gene expression profiles and gastrointestinal maturation in infant mice [0.03%]
微生物胆盐水解酶活性影响幼鼠的基因表达谱和胃肠道成熟进程
María A Núñez-Sánchez,Florence M Herisson,Jonathan M Keane et al.
María A Núñez-Sánchez et al.
The mechanisms by which early microbial colonizers of the neonate influence gut development are poorly understood. Bacterial bile salt hydrolase (BSH) acts as a putative colonization factor that influences bile acid signatures and microbe-h...
Predicting butyrate- and propionate-forming bacteria of gut microbiota from sequencing data [0.03%]
从测序数据预测肠道微生物中产生丁酸和丙酸的细菌
Berenike Kircher,Sabrina Woltemate,Frank Gutzki et al.
Berenike Kircher et al.
The bacteria-derived short-chain fatty acids (SCFAs) butyrate and propionate play important (distinct) roles in health and disease, and understanding the ecology of respective bacteria on a community-wide level is a top priority in microbio...
Atypical enteropathogenic E. coli are associated with disease activity in ulcerative colitis [0.03%]
非典型肠致病性大肠杆菌与溃疡性结肠炎的疾病活动有关
Maximilian Baumgartner,Rebecca Zirnbauer,Sabine Schlager et al.
Maximilian Baumgartner et al.
With increasing urbanization and industrialization, the prevalence of inflammatory bowel diseases (IBDs) has steadily been rising over the past two decades. IBD involves flares of gastrointestinal (GI) inflammation accompanied by microbiota...