FABP4 in Paneth cells regulates antimicrobial protein expression to reprogram gut microbiota [0.03%]
潘氏细胞中的FABP4通过调节抗菌蛋白的表达来重新编程肠道微生物群
Xiaomin Su,Mengli Jin,Chen Xu et al.
Xiaomin Su et al.
Antimicrobial proteins possess a broad spectrum of bactericidal activity and play an important role in shaping the composition of gut microbiota, which is related to multiple diseases such as metabolic syndrome. However, it is incompletely ...
Indole intercepts the communication between enteropathogenic E. coli and Vibrio cholerae [0.03%]
吲哚拦截肠病志贺氏菌和霍乱弧菌间的交流
Orna Gorelik,Alona Rogad,Lara Holoidovsky et al.
Orna Gorelik et al.
Reported numbers of diarrheal samples exhibiting co-infections or multiple infections, with two or more infectious agents, are rising, likely due to advances in bacterial diagnostic techniques. Bacterial species detected in these samples in...
Alterations in gut microbiome and metabolomics in chronic hepatitis B infection-associated liver disease and their impact on peripheral immune response [0.03%]
慢性乙型肝炎感染相关性肝病中肠道微生物群和代谢组的改变及其对周围免疫反应的影响
Yue Shen,Sheng-Di Wu,Yao Chen et al.
Yue Shen et al.
Gut dysbiosis has been reported in chronic hepatitis B (CHB) infection, however its role in CHB progression and antiviral treatment remains to be clarified. Herein, the present study aimed to characterize gut microbiota (GM) in patients wit...
Potential binding modes of the gut bacterial metabolite, 5-hydroxyindole, to the intestinal L-type calcium channels and its impact on the microbiota in rats [0.03%]
肠道细菌代谢产物5-羟色胺与肠L型钙通道的潜在结合模式及其对大鼠菌群的影响
Barbora Waclawiková,Paulo Cesar Telles de Souza,Markus Schwalbe et al.
Barbora Waclawiková et al.
Intestinal microbiota and microbiota-derived metabolites play a key role in regulating the host physiology. Recently, we have identified a gut-bacterial metabolite, namely 5-hydroxyindole, as a potent stimulant of intestinal motility via it...
Stool multi-omics for the study of host-microbe interactions in inflammatory bowel disease [0.03%]
炎症性肠病中宿主与微生物相互作用的粪便多组学研究
Consuelo Sauceda,Charlie Bayne,Khadijeh Sudqi et al.
Consuelo Sauceda et al.
Inflammatory Bowel Disease (IBD) is a chronic immune-mediated inflammatory disease of the gastrointestinal tract that is a growing public burden. Gut microbes and their interactions with hosts play a crucial role in disease pathogenesis and...
From intestinal colonization to systemic infections: Candida albicans translocation and dissemination [0.03%]
从肠道定植到全身感染：白色念珠菌的移位与播散
Jakob L Sprague,Lydia Kasper,Bernhard Hube
Jakob L Sprague
Candida species are the most prevalent cause of invasive fungal infections, of which Candida albicans is the most common. Translocation across the epithelial barrier into the bloodstream by intestinal-colonizing C. albicans cells serves as ...
Enteropathogenic Escherichia coli regulates host-cell mitochondrial morphology [0.03%]
肠致病性大肠杆菌调节宿主细胞线粒体形态
Jennifer Lising Roxas,Shylaja Ramamurthy,Katie Cocchi et al.
Jennifer Lising Roxas et al.
The diarrheagenic pathogen enteropathogenic Escherichia coli is responsible for significant childhood mortality and morbidity. EPEC and related attaching-and-effacing (A/E) pathogens use a type III secretion system to hierarchically deliver...
Preterm infants at low risk for early-onset sepsis differ in early fecal microbiome assembly [0.03%]
早发型败血症低风险的早产儿在早期粪便微生物组组装上存在差异
Sagori Mukhopadhyay,Jung-Jin Lee,Erica Hartman et al.
Sagori Mukhopadhyay et al.
Antibiotics are administered near-universally to very low birth weight (VLBW) infants after birth for suspected early-onset sepsis (EOS). We previously identified a phenotypic group of VLBW infants, referred to as low-risk for EOS (LRE), wh...
Microbial vitamin production mediates dietary effects on diabetic risk [0.03%]
微生物维生素的生产调节饮食对糖尿病风险的影响
Daoming Wang,Van T Pham,Robert E Steinert et al.
Daoming Wang et al.
Adequate levels of essential vitamins are important for the prevention of diabetes. While the main efforts to address this are currently focused on the intake of vitamin supplements, improving and maintaining intrinsic vitamin production ca...
Dysbiotic but nonpathogenic shift in the fecal mycobiota of patients with rheumatoid arthritis [0.03%]
患有类风湿性关节炎患者的粪便霉菌群失调但不具致病性变化
Eun Ha Lee,Hyun Kim,Jung Hee Koh et al.
Eun Ha Lee et al.
Rheumatoid arthritis (RA) is closely associated with the oral and gut microbiomes. Fungal cell wall components initiate inflammatory arthritis in mouse models. However, little is known regarding the role of the fungal community in the patho...