The diagnostic and prognostic potential of gut bacteria in inflammatory bowel disease [0.03%]
肠道细菌在炎症性肠病诊断和预后中的潜力
Dickson Kofi Wiredu Ocansey,Sanhua Hang,Xinyi Yuan et al.
Dickson Kofi Wiredu Ocansey et al.
The gut microbiome serves as a signaling hub that integrates environmental inputs with genetic and immune signals to influence the host's metabolism and immunity. Gut bacteria are intricately connected with human health and disease state, w...
Mouse models for bacterial enteropathogen infections: insights into the role of colonization resistance [0.03%]
细菌肠病原菌感染的小鼠模型：定植抗性的角色启示
Mathias K-M Herzog,Monica Cazzaniga,Audrey Peters et al.
Mathias K-M Herzog et al.
Globally, enteropathogenic bacteria are a major cause of morbidity and mortality.1-3 Campylobacter, Salmonella, Shiga-toxin-producing Escherichia coli, and Listeria are among the top five most commonly reported zoonotic pathogens in the Eur...
Gut microbiome function and composition in infants from rural Kenya and association with human milk oligosaccharides [0.03%]
来自肯尼亚农村的婴儿肠道微生物组功能和组成及其与人乳低聚糖的关系
Muriel Derrien,Nadja Mikulic,Mary A Uyoga et al.
Muriel Derrien et al.
The gut microbiota evolves rapidly after birth, responding dynamically to environmental factors and playing a key role in short- and long-term health. Lifestyle and rurality have been shown to contribute to differences in the gut microbiome...
Using fecal immmunochemical cartridges for gut microbiome analysis within a colorectal cancer screening program [0.03%]
粪便免疫化学试纸在结直肠癌筛查项目中的应用及对肠道菌群分析的影响
Stefanie Brezina,Martin Borkovec,Andreas Baierl et al.
Stefanie Brezina et al.
The colorectal cancer (CRC) screening program B-PREDICT is an invited two-stage screening project using a fecal immunochemical test (FIT) for initial screening followed by a colonoscopy for those with a positive FIT. Since the gut microbiom...
How longitudinal data can contribute to our understanding of host genetic effects on the gut microbiome [0.03%]
纵向数据如何有助于我们了解宿主基因对肠道微生物组的影响
Laura Grieneisen,Ran Blekhman,Elizabeth Archie
Laura Grieneisen
A key component of microbiome research is understanding the role of host genetic influence on gut microbial composition. However, it can be difficult to link host genetics with gut microbial composition because host genetic similarity and e...
Co-cultivation is a powerful approach to produce a robust functionally designed synthetic consortium as a live biotherapeutic product (LBP) [0.03%]
共培养是一种强大的方法，可以产生一种稳健的功能性设计的合成 consortium 作为活生物治疗产品（LBＰ）
Fabienne Kurt,Gabriel E Leventhal,Marianne Rebecca Spalinger et al.
Fabienne Kurt et al.
The success of fecal microbiota transplants (FMT) has provided the necessary proof-of-concept for microbiome therapeutics. Yet, feces-based therapies have many associated risks and uncertainties, and hence defined microbial consortia that m...
Allogeneic hematopoietic cell transplantation, the microbiome, and graft-versus-host disease [0.03%]
同种异体造血细胞移植、微生物群和移植物抗宿主病
Yannouck F van Lier,Jaël Vos,Bianca Blom et al.
Yannouck F van Lier et al.
Many patients with hematological malignancies, such as acute myeloid leukemia, receive an allogeneic hematopoietic cell transplantation (HCT) to cure their underlying condition. Allogeneic HCT recipients are exposed to various elements duri...
Gluten-free diet affects fecal small non-coding RNA profiles and microbiome composition in celiac disease supporting a host-gut microbiota crosstalk [0.03%]
无麸质饮食影响粪便中小非编码RNA谱型和乳糜泻中肠道菌群的组成，支持宿主与肠道菌群之间的相互作用
Antonio Francavilla,Giulio Ferrero,Barbara Pardini et al.
Antonio Francavilla et al.
Current treatment for celiac disease (CD) is adhering to a gluten-free diet (GFD), although its long-term molecular effects are still undescribed. New molecular features detectable in stool may improve and facilitate noninvasive clinical ma...
Observational Study
Gut microbes. 2023 Jan-Dec;15(1):2172955. DOI:10.1080/19490976.2023.2172955 2023
Segmented filamentous bacteria impede rotavirus infection via retinoic acid receptor-mediated signaling [0.03%]
分段丝状细菌通过视黄酸受体介导的信号传导阻碍轮状病毒感染
Vu L Ngo,Zhenda Shi,Baoming Jiang et al.
Vu L Ngo et al.
Prevention of rotavirus (RV) infection by gut-resident segmented filamentous bacteria (SFB) is an example of the influence of gut microbiota composition on enteric viral infection. Yet, the mechanism by which SFB prevents RV infection is po...
Bile acids as modulators of gut microbiota composition and function [0.03%]
胆酸通过调节肠道菌群的组成和功能参与代谢性疾病发生发展过程中的相互作用关系研究进展
Anaïs B Larabi,Hugo L P Masson,Andreas J Bäumler
Anaïs B Larabi
Changes in the composition of gut-associated microbial communities are associated with many human illnesses, but the factors driving dysbiosis remain incompletely understood. One factor governing the microbiota composition in the gut is bil...