Actively replicating gut bacteria identified by 5-ethynyl-2'-deoxyuridine (EdU) click chemistry and cell sorting [0.03%]
利用点击化学和细胞分选鉴定活跃复制的肠道细菌
Eve T Beauchemin,Claire Hunter,Corinne F Maurice
Eve T Beauchemin
The composition of the intestinal bacterial community is well described, but recent research suggests that the metabolism of these bacteria plays a larger role in health than which species are present. One fundamental aspect of gut bacteria...
Austin Yan,James Butcher,Laetitia Schramm et al.
Austin Yan et al.
The human gut virome has been increasingly explored in recent years. However, nearly all virome-sequencing efforts rely solely on fecal samples and few studies leverage multiomic approaches to investigate phage-host relationships. Here, we ...
Daniel Tchelet,Kinga Keppel,Eran Bosis et al.
Daniel Tchelet et al.
All strains of the marine bacterium Vibrio parahaemolyticus harbor a type VI secretion system (T6SS) named T6SS2, suggesting that this system plays an important role in the life cycle of this emerging pathogen. Although T6SS2 was recently s...
Randomized controlled trial demonstrates response to a probiotic intervention for metabolic syndrome that may correspond to diet [0.03%]
一项随机对照试验显示某种益生菌干预对代谢综合征有疗效且与饮食相关
Hannah C Wastyk,Dalia Perelman,Madeline Topf et al.
Hannah C Wastyk et al.
An individual's immune and metabolic status is coupled to their microbiome. Probiotics offer a promising, safe route to influence host health, possibly via the microbiome. Here, we report an 18-week, randomized prospective study that explor...
Randomized Controlled Trial
Gut microbes. 2023 Jan-Dec;15(1):2178794. DOI:10.1080/19490976.2023.2178794 2023
Gut microbiome composition is associated with long-term disability worsening in multiple sclerosis [0.03%]
肠道微生物群组成与多发性硬化症长期残疾恶化的相关性
Lindsay Devolder,Ayla Pauwels,Ann Van Remoortel et al.
Lindsay Devolder et al.
Predicting the long-term outcome of multiple sclerosis (MS) remains an important challenge to this day. As the gut microbiota is emerging as a potential player in MS, we investigated in this study whether gut microbial composition at baseli...
Salmonella effector SopF regulates PANoptosis of intestinal epithelial cells to aggravate systemic infection [0.03%]
沙门氏菌效应蛋白SopF通过调节肠道上皮细胞PANoptosis来加重全身感染
Haibo Yuan,Liting Zhou,Yilin Chen et al.
Haibo Yuan et al.
SopF, a newly discovered effector secreted by Salmonella pathogenicity island-1 type III secretion system (T3SS1), was reported to target phosphoinositide on host cell membrane and aggravate systemic infection, while its functional relevanc...
Inulin increases the beneficial effects of rhubarb supplementation on high-fat high-sugar diet-induced metabolic disorders in mice: impact on energy expenditure, brown adipose tissue activity, and microbiota [0.03%]
鼠茅菜多糖增强番泻黄茋对高脂高糖小鼠代谢紊乱的有益作用：能量消耗，棕色脂肪组织活性和微生物群的影响
Marion Régnier,Matthias Van Hul,Martin Roumain et al.
Marion Régnier et al.
Consumption of prebiotics and plant-based compounds have many beneficial health effects through modulation of gut microbiota composition and are considered as promising nutritional strategy for the treatment of metabolic diseases. In the pr...
Neonatal necrotizing enterocolitis: Clostridium butyricum and Clostridium neonatale fermentation metabolism and enteropathogenicity [0.03%]
新生儿坏死性小肠结肠炎：产丁酸克氏菌和新生菌的发酵代谢及肠道致病性
Laurent Ferraris,Aurélie Balvay,Deborah Bellet et al.
Laurent Ferraris et al.
Bacterial colonization in the gut plays a pivotal role in neonatal necrotizing enterocolitis (NEC) development, but the relationship between bacteria and NEC remains unclear. In this study, we aimed to elucidate whether bacterial butyrate e...
The fecal microbiotas of women of Pacific and New Zealand European ethnicities are characterized by distinctive enterotypes that reflect dietary intakes and fecal water content [0.03%]
太平洋岛民和新西兰高加索人的粪便菌群具有独特的菌型表型，反映他们的膳食摄入以及粪便含水量的差异
Nikki Renall,Blair Lawley,Tommi Vatanen et al.
Nikki Renall et al.
Obesity is a complex, multifactorial condition that is an important risk factor for noncommunicable diseases including cardiovascular disease and type 2 diabetes. While prevention and management require a healthy and energy balanced diet an...
Limosilactobacillus reuteri normalizes blood-brain barrier dysfunction and neurodevelopment deficits associated with prenatal exposure to lipopolysaccharide [0.03%]
刘氏乳杆菌通过改善妊娠期内毒素暴露诱导的血脑屏障功能异常来促进神经发育
Jing Lu,Xiaobing Fan,Lei Lu et al.
Jing Lu et al.
Maternal immune activation (MIA) derived from late gestational infection such as seen in chorioamnionitis poses a significantly increased risk for neurodevelopmental deficits in the offspring. Manipulating early microbiota through maternal ...