Probiotics to improve the gut microbiome in premature infants: are we there yet? [0.03%]
益生菌改善早产儿肠道微生态：我们准备好了吗？
Emily M Mercer,Marie-Claire Arrieta
Emily M Mercer
Gut microbiome maturation in infants born prematurely is uniquely influenced by the physiological, clinical, and environmental factors surrounding preterm birth and early life, leading to altered patterns of microbial succession relative to...
Employing pigs to decipher the host genetic effect on gut microbiome: advantages, challenges, and perspectives [0.03%]
利用猪解析肠道微生物组的宿主遗传效应：优势、挑战与前景展望
Lusheng Huang,Congying Chen
Lusheng Huang
The gut microbiota is a complex and diverse ecosystem comprised of trillions of microbes and plays an essential role in host's immunity, metabolism, and even behaviors. Environmental and host factors drive the huge variations in the gut mic...
Diverse but desolate landscape of gut microbial azoreductases: A rationale for idiopathic IBD drug response [0.03%]
异基因肠道微生物脱氧酶多样但荒芜的景观：对特发性炎症性肠病药物反应的一个解释
Joshua B Simpson,Josh J Sekela,Benjamin S Carry et al.
Joshua B Simpson et al.
Prodrugs reliant on microbial activation are widely used but exhibit a range of efficacies that remain poorly understood. The anti-inflammatory compound 5-aminosalicylic acid (5-ASA), which is packaged in a variety of azo-linked prodrugs pr...
Epidemiological and microbiome associations of Clostridioides difficile carriage in infancy and early childhood [0.03%]
婴儿和幼儿携带难辨梭菌的流行病学及微生物组特征研究
Jyoti Mani,Shira Levy,Angelina Angelova et al.
Jyoti Mani et al.
There has been an increase in the prevalence of Clostridioides difficile (C. diff) causing significant economic impact on the health care system. Although toxigenic C. diff carriage is recognized in infancy, there is limited data regarding ...
Microbial metabolites in colorectal tumorigenesis and cancer therapy [0.03%]
肠道微生物代谢产物在结直肠肿瘤发生及癌症治疗中的作用
Yali Liu,Harry Cheuk-Hay Lau,Jun Yu
Yali Liu
Trillions of microbes are indigenous to the human gastrointestinal tract, together forming an ecological community known as the gut microbiota. The gut microbiota is involved in dietary digestion to produce various metabolites. In healthy c...
A distinct microbiota signature precedes the clinical diagnosis of hepatocellular carcinoma [0.03%]
肝细胞癌临床诊断前独特的微生物特征.signature
Jinhuan Yang,Qikuan He,Fei Lu et al.
Jinhuan Yang et al.
Oral, gut, and tumor microbiota have been implicated as important regulators in the carcinogenesis and progression of gastrointestinal malignancies. However, few studies focused on the existence and association of resident microbes within d...
Gut microbiome at the crossroad of genetic variants and behavior disorders [0.03%]
肠道微生物组位于遗传变异和行为障碍的交叉路口
Lingsha Cheng,Haoqian Wu,Zhuo Chen et al.
Lingsha Cheng et al.
Genetic variants are traditionally known to shape the susceptibility to neuropsychiatric disorders. An increasing number of studies indicate that remodeling of the gut microbiome by genetic variance serves as a versatile regulator of gut-br...
Effects of dietary fibers or probiotics on functional constipation symptoms and roles of gut microbiota: a double-blinded randomized placebo trial [0.03%]
饮食纤维或益生菌对功能性便秘的症状影响及其肠道菌群作用：一项双盲随机对照试验
Hao Lai,Yunfeng Li,Yafang He et al.
Hao Lai et al.
Dietary fibers/probiotics may relieve constipation via optimizing gut microbiome, yet with limited trial-based evidences. We aimed to evaluate the effects of formulas with dietary fibers or probiotics on functional constipation symptoms, an...
Randomized Controlled Trial
Gut microbes. 2023 Jan-Dec;15(1):2197837. DOI:10.1080/19490976.2023.2197837 2023
Bingqian Zhou,Xiaoqi Pang,Jingyi Wu et al.
Bingqian Zhou et al.
The epidemic of coronavirus disease-19 (COVID-19) has grown to be a global health threat. Gastrointestinal symptoms are thought to be common clinical manifestations apart from a series of originally found respiratory symptoms. The human gut...
The emerging role of the small intestinal microbiota in human health and disease [0.03%]
人类健康和疾病中肠菌群的作用不容忽视
Renate A A A Ruigrok,Rinse K Weersma,Arnau Vich Vila
Renate A A A Ruigrok
The human gut microbiota continues to demonstrate its importance in human health and disease, largely owing to the countless number of studies investigating the fecal microbiota. Underrepresented in these studies, however, is the role playe...