Maternal microbiome disturbance induces deficits in the offspring's behaviors: a systematic review and meta-analysis [0.03%]
母体微生物群紊乱会导致子代行为缺陷：系统性回顾和荟萃分析
Lucas Hassib,Cilene Lino de Oliveira,Guilherme Araujo Rouvier et al.
Lucas Hassib et al.
Recent evidence has suggested that changes in maternal gut microbiota in early life may generate neurobiological consequences associated with psychiatric-related abnormalities. However, the number of studies on humans investigating this pro...
Diet high in linoleic acid dysregulates the intestinal endocannabinoid system and increases susceptibility to colitis in Mice [0.03%]
富含亚油酸饮食通过紊乱肠内源性大麻素系统增加小鼠结肠炎易感性
Poonamjot Deol,Paul Ruegger,Geoffrey D Logan et al.
Poonamjot Deol et al.
Inflammatory bowel disease (IBD) is a multifactorial disease with increasing incidence in the U.S. suggesting that environmental factors, including diet, are involved. It has been suggested that excessive consumption of linoleic acid (LA, C...
Fecal microbiota transplantation in hematopoietic cell transplant and cellular therapy recipients: lessons learned and the path forward [0.03%]
造血细胞移植和细胞治疗受者粪便微生物群移植的经验与展望
Shaghayegh Habibi,Armin Rashidi
Shaghayegh Habibi
Disruptions to the gut microbiota have been associated with adverse outcomes including graft-versus-host disease, infections, and mortality after hematopoietic cell transplantation and cellular therapy. Evidence for causal links is accumula...
Héloïse Rytter,Emilie Combet,Benoit Chassaing
Héloïse Rytter
Discovered at the beginning of the 20th century by Nobel laureate Élie Metchnikoff, probiotics have more recently emerged as a potential noninvasive therapeutic approach for the treatment of various chronic diseases. However, recent popula...
Neglected gut microbiome: interactions of the non-bacterial gut microbiota with enteric pathogens [0.03%]
被忽视的肠道微生物组：肠道病原体与非细菌性肠道微生物之间的相互作用
Kanchan Jaswal,Olivia A Todd,Judith Behnsen
Kanchan Jaswal
A diverse array of commensal microorganisms inhabits the human intestinal tract. The most abundant and most studied members of this microbial community are undoubtedly bacteria. Their important role in gut physiology, defense against pathog...
Dietary sugars silence the master regulator of carbohydrate utilization in human gut Bacteroides species [0.03%]
饮食糖分使人类肠道细菌Bacteroides属的碳水化合物利用主调节因子失活
Victoria H Pearce,Eduardo A Groisman,Guy E Townsend nd
Victoria H Pearce
The mammalian gut microbiota is a critical human health determinant with therapeutic potential for remediation of many diseases. The host diet is a key factor governing the gut microbiota composition by altering nutrient availability and su...
Microbiome-targeting therapies in the neonatal intensive care unit: safety and efficacy [0.03%]
新生儿重症监护病房中针对微生物组的治疗：安全性和有效性
Anna DeVeaux,Jian Ryou,Gautam Dantas et al.
Anna DeVeaux et al.
Microbiome-targeting therapies have received great attention as approaches to prevent disease in infants born preterm, but their safety and efficacy remain uncertain. Here we summarize the existing literature, focusing on recent meta-analys...
L-arginine metabolism as pivotal interface of mutual host-microbe interactions in the gut [0.03%]
肠腔内宿主-微生物互作中的L-精氨酸代谢界面作用机制研究
Björn Nüse,Tim Holland,Manfred Rauh et al.
Björn Nüse et al.
L-arginine (L-arg) is a versatile amino acid and a central intestinal metabolite in mammalian and microbial organisms. Thus, L-arg participates as precursor of multiple metabolic pathways in the regulation of cell division and growth. It al...
Key bacterial taxa determine longitudinal dynamics of aromatic amino acid catabolism in infants' gut [0.03%]
关键细菌种群决定了婴儿肠道芳香族氨基酸分解的纵向动态变化
Martin F Laursen,Anurag K Sinha,Mikael Pedersen et al.
Martin F Laursen et al.
The development of the gut microbiota in early life is linked to metabolic, neuronal, and immunological development. Recent studies have shown that bacterial production of short-chain fatty acids (SCFAs) and aromatic amino acid (AAA) catabo...
Machine learning model for predicting age in healthy individuals using age-related gut microbes and urine metabolites [0.03%]
基于年龄相关肠道菌群和尿液代谢物预测健康个体年龄的机器学习模型
Seung-Ho Seo,Chang-Su Na,Seong-Eun Park et al.
Seung-Ho Seo et al.
Age-related gut microbes and urine metabolites were investigated in 568 healthy individuals using metataxonomics and metabolomics. The richness and evenness of the fecal microbiota significantly increased with age, and the abundance of 16 g...