Fucose promotes intestinal stem cell-mediated intestinal epithelial development through promoting Akkermansia-related propanoate metabolism [0.03%]
岩藻糖通过促进阿克曼氏菌相关丙酸代谢促进肠道干细胞介导的肠道上皮发育
Caihan Duan,Junhao Wu,Zhe Wang et al.
Caihan Duan et al.
Intestinal stem cells (ISCs) are critical for the development and rapid turnover of intestinal epithelium. The regulatory effects of gut microbiota and their metabolites on ISCs stemness remain elusive. Fucose has been demonstrated to media...
Runze Ouyang,Juan Ding,Yan Huang et al.
Runze Ouyang et al.
The gut microbiota is involved in the production of numerous metabolites that maintain host wellbeing. The assembly of the gut microbiome is highly dynamic, and influenced by many postnatal factors, moreover, little is known about the devel...
Akkermansia muciniphila reduces susceptibility to Listeria monocytogenes infection in mice fed a high-fat diet [0.03%]
高脂饮食喂养的小鼠感染单核细胞增生李斯特菌的易感性降低与Akkermansia muciniphila有关
Jonathan M Keane,Vanessa Las Heras,Jorge Pinheiro et al.
Jonathan M Keane et al.
A high-fat (HF) diet reduces resistance to the foodborne pathogen Listeria monocytogenes. We demonstrate that short-term gavage with A. muciniphila increases resistance to oral and systemic L. monocytogenes infection in mice fed a HF diet. ...
Dynamic effects of probiotic formula ecologic®825 on human small intestinal ileostoma microbiota: a network theory approach [0.03%]
生态板公式ecologic®825对人类小肠微生物组的动态影响：网络理论方法
Jack Jansma,Nicola U Thome,Markus Schwalbe et al.
Jack Jansma et al.
The gut microbiota plays a pivotal role in health and disease. The use of probiotics as microbiota-targeted therapies is a promising strategy to improve host health. However, the molecular mechanisms involved in such therapies are often not...
Cytotoxic necrotizing factor 1 hinders colon tumorigenesis induced by colibactin-producing Escherichia coli in ApcMin/+ mice [0.03%]
细胞毒性坏死因子1能抑制产colibactin大肠杆菌诱导的ApcMin/+小鼠结肠肿瘤发生发展
Héloïse Chat,Guillaume Dalmasso,Catherine Godfraind et al.
Héloïse Chat et al.
Colorectal cancer (CRC) patients are frequently colonized by colibactin-producing Escherichia coli (CoPEC) (>40%), which enhances tumorigenesis in mouse models of CRC. We observed that 50% of CoPEC also contains the cnf1 gene, which encodes...
High variation across E. coli hybrid isolates identified in metabolism-related biological pathways co-expressed with virulent genes [0.03%]
参与致病基因共表达的代谢相关途径在埃希氏杆菌杂交分离物中高度变异
Rahul Gomes,Ashleigh Denison Kroschel,Stephanie Day et al.
Rahul Gomes et al.
Virulent genes present in Escherichia coli (E. coli) can cause significant human diseases. These enteropathogenic E. coli (EPEC) and enterotoxigenic E. coli (ETEC) isolates with virulent genes show different expression levels when grown und...
Strain-level screening of human gut microbes identifies Blautia producta as a new anti-hyperlipidemic probiotic [0.03%]
人肠道微生物菌株水平筛选鉴定出一种抗高血脂益生菌Blautia producta
Wenyi Xu,Jiaqi Yu,Yanan Yang et al.
Wenyi Xu et al.
Compelling evidence has tightly linked gut microbiota with host metabolism homeostasis and inspired novel therapeutic potentials against metabolic diseases (e.g., hyperlipidemia). However, the regulatory profile of individual bacterial spec...
Limosilactobacillus reuteri DSM 17938 supplementation and SARS-CoV-2 specific antibody response in healthy adults: a randomized, triple-blinded, placebo-controlled trial [0.03%]
鼠李糖乳杆菌(Limosilactobacillus reuteri)DSM 17938干预对健康成人SARS-CoV-2特异性抗体反应的影响：一项随机、三盲、安慰剂对照试验
Richard A Forsgård,Julia Rode,Karin Lobenius-Palmér et al.
Richard A Forsgård et al.
Studies have shown that probiotics can decrease the symptoms of respiratory tract infections as well as increase antibody responses following certain vaccinations. We examined the effect of probiotic supplementation on anti-SARS-CoV-2 speci...
Randomized Controlled Trial
Gut microbes. 2023 Jan-Dec;15(1):2229938. DOI:10.1080/19490976.2023.2229938 2023
Adrianna Aleksandrowicz,Ewa Carolak,Agata Dutkiewicz et al.
Adrianna Aleksandrowicz et al.
Salmonella poses a serious threat to public health and socioeconomic development worldwide because of its foodborne pathogenicity and antimicrobial resistance. This biofilm-planktonic lifestyle enables Salmonella to interfere with the host ...
In vitro adhesion, pilus expression, and in vivo amelioration of antibiotic-induced microbiota disturbance by Bifidobacterium spp. strains from fecal donors [0.03%]
双歧杆菌菌株的体外黏附、菌毛表达及改善抗生素诱导的肠道微生物群紊乱的作用
Aki Ronkainen,Imran Khan,Eva Krzyżewska-Dudek et al.
Aki Ronkainen et al.
Fecal microbiota transplantation (FMT) is used routinely to treat recurrent Clostridioides difficile infection (rCDI) and investigated as a treatment for numerous conditions associated with gut microbiota alterations. Metagenomic analyses h...