De novo clustering of long-read amplicons improves phylogenetic insight into microbiome data [0.03%]
从长读取扩增子脱机聚类可提高微生物组数据的系统发育见解
Yan Hui,Dennis Sandris Nielsen,Lukasz Krych
Yan Hui
Long-read amplicon profiling through read classification limits phylogenetic analysis of amplicons while community analysis of multicopy genes, relying on unique molecular identifier (UMI) corrections, often demands deep sequencing. To addr...
Tips and tricks for gut microbiota investigation using scanning electron microscopy (SEM): going from sample preparation to imaging and landscape analysis [0.03%]
基于扫描电子显微镜技术的肠道微生物研究：从样本制备到图像采集及景观分析的一系列技巧和心得
Meriem Boukili,Omar Zmerli,Florence Fenollar et al.
Meriem Boukili et al.
The Gut Microbiota (GM) remains a complex microbial ecosystem with many unknown facets despite significant technologic advancement. This study introduces a novel rapid technique using tabletop scanning electron microscopy (SEM) for investig...
Effect of short-term dietary intervention on fecal serotonin, gut microbiome-derived tryptophanase, and energy absorption in a randomized crossover trial: an exploratory analysis [0.03%]
短期饮食干预对粪便血清素、肠道菌群来源的吲哚酶及能量吸收的影响：一项随机交叉试验的探索性分析
Eiichi Yoshimura,Yuka Hamada,Yoichi Hatamoto et al.
Eiichi Yoshimura et al.
In this study, we investigated the effects of short-term energy loads on changes in gut microbiome-derived tryptophanase and fecal serotonin levels and their association with variations in energy absorption. This randomized crossover energy...
Randomized Controlled Trial
Gut microbes. 2025 Dec;17(1):2514137. DOI:10.1080/19490976.2025.2514137 2025
Grace Tang,Ewan K A Millar,Peter H Graham et al.
Grace Tang et al.
Previously believed to be sterile, the breast microenvironment has been revealed by modern DNA sequencing technologies to harbor a diverse community of microorganisms. The breast tumor microenvironment (TME) has a microbial signature unique...
L-serine promotes pro-carcinogenic effects of colibactin-producing E. coli [0.03%]
L-丝氨酸促进产colibactin大肠杆菌的促致癌作用
Amandine Devaux,Romain Villéger,Gwenaëlle Roche et al.
Amandine Devaux et al.
Colonic tissues are abnormally colonized by colibactin-producing Escherichia coli (CoPEC) in colorectal cancer (CRC) patients. CoPECs have been shown to promote colorectal carcinogenesis in several pre-clinical CRC mouse models. Here, we re...
Chikungunya virus drives gut microbiota shifts and IFN-Mediated intestinal repair: insights into microbiota-immune interplay [0.03%]
Chicungunya病毒驱动肠道微生物群变化和IFN介导的肠修复：探讨微生物群-免疫互作的见解
Hongyu Chen,Kaiyun Ding,Cong Tang et al.
Hongyu Chen et al.
Chikungunya virus (CHIKV) infection causes joint damage and gastrointestinal clinical symptoms, including vomiting and diarrhea, particularly in elderly populations, reflecting the potential role of gut immunity in infection. However, the m...
Implications of gut microbiota-mediated epigenetic modifications in intestinal diseases [0.03%]
肠道微生物介导的表观遗传修饰改变在肠病中的作用及机制研究
Qihong Zhang,Yun Liu,Yuheng Li et al.
Qihong Zhang et al.
Intestinal diseases are highly prevalent, affecting millions worldwide and significantly contributing to global morbidity. The treatment of complex disorders, such as inflammatory bowel disease (IBD) and colorectal cancer (CRC), remains cha...
Impact of peripheral circadian misalignment and alcohol on the resiliency of intestinal barrier and microbiota [0.03%]
外周生物钟紊乱和酒精对肠屏障功能及肠道微生物组成的影响
Laura Tran,Maliha Shaikh,Phillip A Engen et al.
Laura Tran et al.
Circadian organization is involved in many gastrointestinal tract (GIT) functions such as the maintenance of intestinal barrier integrity. There is compelling evidence that perturbation of the circadian clock decreases intestinal epithelial...
Addressing controversy in Fusobacterium nomenclature: what exactly does " F. nucleatum" refer to? [0.03%]
如何解决弗梭菌分类命名中的争议：“F. nucleatum”具体指什么？
Martha A Zepeda-Rivera,Floyd E Dewhirst,Susan Bullman et al.
Martha A Zepeda-Rivera et al.
The F. nucleatum group (sensu lato) is historically composed of four subspecies (F. nucleatum subsp. animalis, F. nucleatum subsp. nucleatum, F. nucleatum subsp. polymorphum, F. nucleatum subsp. vincentii). Although F. nucleatum sensu lato ...
Antidepressant drugs promote the spread of broad-host-range plasmid in mouse and human gut microbiota [0.03%]
抗抑郁药物促进小鼠和人类肠道微生物群广宿主谱质粒的传播
Pengbo Ding,Ji Lu,Tong Lei et al.
Pengbo Ding et al.
Antibiotic resistance is a global public health challenge. The gut microbiota serves as a reservoir for antibiotic resistance genes (ARGs), facilitating their transfer between bacteria. With the rising incidence of major depressive disorder...