Microbial stimulation of oxytocin release from the intestinal epithelium via secretin signaling [0.03%]
肠上皮细胞通过促胰液素信号促进微生物诱导的催产素释放
Heather A Danhof,Jihwan Lee,Aanchal Thapa et al.
Heather A Danhof et al.
Intestinal microbes impact the health of the intestine and organs distal to the gut. Limosilactobacillus reuteri is a human intestinal microbe that promotes normal gut transit, the anti-inflammatory immune system, wound healing, normal soci...
Host miR-129-5p reverses effects of ginsenoside Rg1 on morphine reward possibly mediated by changes in B. vulgatus and serotonin metabolism in hippocampus [0.03%]
宿主miR-129-5p可能通过改变鼠李糖乳杆菌和海马中血清素代谢逆转人参皂苷Rg1对吗啡奖赏的作用
Chan Li,Yingbo Lin,Rukun Lin et al.
Chan Li et al.
Morphine addiction is closely associated with dysbiosis of the gut microbiota. miRNAs play a crucial role in regulating intestinal bacterial growth and are involved in the development of disease. Ginsenoside Rg1 exhibits an anti-addiction e...
Targeting microbial quorum sensing: the next frontier to hinder bacterial driven gastrointestinal infections [0.03%]
靶向微生物群体感应：阻止细菌引发的胃肠道感染的下一个前沿领域
Ying Su,Tao Ding
Ying Su
Bacteria synchronize social behaviors via a cell-cell communication and interaction mechanism termed as quorum sensing (QS). QS has been extensively studied in monocultures and proved to be intensively involved in bacterial virulence and in...
Obesity is the main driver of altered gut microbiome functions in the metabolically unhealthy [0.03%]
肥胖是代谢不健康个体肠道微生物组功能改变的主要驱动因素
Jacobo de la Cuesta-Zuluaga,Kelsey E Huus,Nicholas D Youngblut et al.
Jacobo de la Cuesta-Zuluaga et al.
Obesity (OB) and cardiometabolic disease are major public health issues linked to changes in the gut microbiome. OB and poor cardiometabolic health status (CHS) are often comorbid, which hinders efforts to identify components of the microbi...
Lactobacillus johnsonii N6.2 phospholipids induce immature-like dendritic cells with a migratory-regulatory-like transcriptional signature [0.03%]
约翰逊乳杆菌N6.2磷脂诱导出一种具有迁移调节特征转录信号的树突状细胞亚型
Alexandra E Cuaycal,Leandro Dias Teixeira,Graciela L Lorca et al.
Alexandra E Cuaycal et al.
Shifts in the gut microbiota composition, called dysbiosis, have been directly associated with acute and chronic diseases. However, the underlying biological systems connecting gut dysbiosis to systemic inflammatory pathologies are not well...
Akkermansia muciniphila supplementation prevents cognitive impairment in sleep-deprived mice by modulating microglial engulfment of synapses [0.03%]
Akkermansia muciniphila补充通过调节小胶质细胞吞噬突触功能预防睡眠剥夺小鼠的认知障碍
Na Li,Shuwen Tan,Yue Wang et al.
Na Li et al.
The microbiome-gut-brain axis plays a crucial role in many neurological diseases, including mild cognitive impairment. Sleep deprivation (SD) induces cognitive decline accompanied by alterations in the gut microbiota. However, the role of g...
Gut microbiota from patients with COVID-19 cause alterations in mice that resemble post-COVID symptoms [0.03%]
从COVID-19患者肠道微生物群中分离的菌株可导致小鼠出现类似长新冠的症状
Viviani Mendes de Almeida,Daiane F Engel,Mayra F Ricci et al.
Viviani Mendes de Almeida et al.
Long-term sequelae of coronavirus disease (COVID)-19 are frequent and of major concern. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection affects the host gut microbiota, which is linked to disease severity in patients ...
Activation of Nod2 signaling upon norovirus infection enhances antiviral immunity and susceptibility to colitis [0.03%]
诺如病毒感染激活Nod2信号促进抗病毒免疫并促发结肠炎易感性
Ghaffar Muharram,Marion Thépaut,Pierre-Emmanuel Lobert et al.
Ghaffar Muharram et al.
Over 90% of epidemic non-bacterial gastroenteritis are caused by human noroviruses (NoVs), which persist in a substantial subset of people allowing their spread worldwide. This has led to a significant number of endemic cases and up to 70,0...
Ring1a protects against colitis through regulating mucosal immune system and colonic microbial ecology [0.03%]
RING1A通过调节黏膜免疫系统和结肠微生物生态学抵抗结肠炎
Yashu Wang,Qianru Li,Jiayu Zhang et al.
Yashu Wang et al.
Inflammatory bowel disease (IBD) represents a prominent chronic immune-mediated inflammatory disorder, yet its etiology remains poorly comprehended, encompassing intricate interactions between genetics, immunity, and the gut microbiome. Thi...
Nehal Adel Abdelsalam,Shaimaa M Hegazy,Ramy K Aziz
Nehal Adel Abdelsalam
Prevotella copri is an abundant member of the human gastrointestinal microbiome, whose relative abundance has curiously been associated with positive and negative impacts on diseases, such as Parkinson's disease and rheumatoid arthritis. Ye...