Targeting gut microbiota: new therapeutic opportunities in multiple sclerosis [0.03%]
靶向肠道微生物群：多发性硬化治疗的新机遇
Dorota Kujawa,Lukasz Laczmanski,Slawomir Budrewicz et al.
Dorota Kujawa et al.
Multiple sclerosis (MS) causes long-lasting, multifocal damage to the central nervous system. The complex background of MS is associated with autoimmune inflammation and neurodegeneration processes, and is potentially affected by many contr...
Mi Young Lim,Young-Do Nam
Mi Young Lim
As the proportion of older people in the world's population steadily increases, there is an urgent need to identify ways to support healthy aging. The gut microbiome has been proposed to be involved in aging-related diseases and has become ...
Alterations in intestinal Archaea composition in pediatric patients with Crohn's disease based on next-generation sequencing - a pilot study [0.03%]
基于下一代测序技术的儿童克罗恩病患者肠道古菌群变化的初步研究
A Krawczyk,T Gosiewski,B Zapała et al.
A Krawczyk et al.
Intestinal dysbiosis can lead to the induction of systemic immune-mediated inflammatory diseases, such as Crohn's disease Although archaea are part of the commensal microbiota, they are still one of the least studied microorganisms. The aim...
GlcNac produced by the gut microbiome enhances host influenza resistance by modulating NK cells [0.03%]
肠道微生物产生的GlcNac通过调节NK细胞增强宿主对流感的抵抗力
Xiaotong Hu,Xiaolu Sun,Ya Zhao et al.
Xiaotong Hu et al.
Microbiota are known to modulate the host response to influenza infection, but the mechanisms remain largely unknown. Gut metabolites are the key mediators through which gut microbes play anti-influenza effect. Transferring fecal metabolite...
Modulating the gut microbiota is involved in the effect of low-molecular-weight Glycyrrhiza polysaccharide on immune function [0.03%]
甘草低聚糖通过调节肠道菌群改善机体免疫功能
Wangdi Song,Yunyun Wang,Gongcheng Li et al.
Wangdi Song et al.
Low molecular weight (6.5 kDa) Glycyrrhiza polysaccharide (GP) exhibits good immunomodulatory activity, however, the mechanism underlying GP-mediated regulation of immunity and gut microbiota remains unclear. In this study, we aimed to reve...
Gut microbiota and child behavior in early puberty: does child sex play a role? [0.03%]
肠道微生物组与青春期早期儿童行为：儿童性别起到作用吗？
Yangwenshan Ou,Eline Rots,Clara Belzer et al.
Yangwenshan Ou et al.
A growing number of studies have indicated relations between the gut microbiota and mental health. However, to date, there is a scarcity of microbiota studies in community samples in early puberty. The current preregistered study (https://o...
Gut microbiota and tumor-associated macrophages: potential in tumor diagnosis and treatment [0.03%]
肠道微生物群和肿瘤相关巨噬细胞：在肿瘤诊断和治疗中的潜力
Dongqin Zhou,Yongsheng Li
Dongqin Zhou
Avoiding immune destruction and polymorphic microbiomes are two key hallmarks of cancer. The tumor microenvironment (TME) is essential for the development of solid tumors, and the function of tumor-associated macrophages (TAMs) in the TME i...
Gut microbiota regulates postprandial GLP-1 response via ileal bile acid-TGR5 signaling [0.03%]
肠道菌群通过回肠胆汁酸-TGR5信号通路调节餐后GLP-1反应
Qiaoling Wang,Huibin Lin,Chongrong Shen et al.
Qiaoling Wang et al.
The gut microbiota interacts with intestinal epithelial cells through microbial metabolites to regulate the release of gut hormones. We investigated whether the gut microbiota affects the postprandial glucagon-like peptide-1 (GLP-1) respons...
Functional profiling of gut microbial and immune responses toward different types of dietary fiber: a step toward personalized dietary interventions [0.03%]
功能性分析肠道微生物和免疫对不同类型膳食纤维的反应：迈向个性化饮食干预的第一步
Jian Tan,Rosilene V Ribeiro,Christopher Barker et al.
Jian Tan et al.
Dietary fiber plays a crucial role in maintaining gut and overall health. The objective of this study was to investigate whether different types of dietary fiber elicited specific changes in gut microbiota composition and the production of ...
Tao Zhang,Guangqi Gao,Lai-Yu Kwok et al.
Tao Zhang et al.
The advent of high-throughput 'omics' technologies has improved our knowledge of gut microbiome in human health and disease, including Alzheimer's disease (AD), a neurodegenerative disorder. Frequent bidirectional communications and mutual ...