Human breastmilk-derived Bifidobacterium longum subsp. infantis CCFM1269 regulates bone formation by the GH/IGF axis through PI3K/AKT pathway [0.03%]
人乳源长双歧杆菌CCFM1269通过PI3K/AKT信号途径调节生长激素/胰岛素样生长因子轴促进骨形成
Mengfan Ding,Bowen Li,Haiqin Chen et al.
Mengfan Ding et al.
Bifidobacterium longum subsp. infantis is a prevalent member of the gut microbiota of breastfed infants. In this study, the effects of human breastmilk-derived B.longum subsp. infantis CCFM1269 on bone formation in developing BALB/c mice we...
Cytolethal distending toxin B inoculation leads to distinct gut microtypes and IBS-D-like microRNA-mediated gene expression changes in a rodent model [0.03%]
一种啮齿动物模型中的细胞致死膨胀毒素B注射导致特异的肠道微生物类型和IBS-D样microRNA介导的基因表达变化
Gabriela Leite,Juliana de Freitas Germano,Walter Morales et al.
Gabriela Leite et al.
Diarrhea-predominant irritable bowel syndrome (IBS-D), associated with increased intestinal permeability, inflammation, and small intestinal bacterial overgrowth, can be triggered by acute gastroenteritis. Cytolethal distending toxin B (Cdt...
Opioid-induced dysbiosis of maternal gut microbiota during gestation alters offspring gut microbiota and pain sensitivity [0.03%]
孕产妇阿片类药物诱导的肠道菌群紊乱影响子代肠道菌群和痛觉敏感性
Yaa F Abu,Salma Singh,Junyi Tao et al.
Yaa F Abu et al.
There has been a rapid increase in neonates born with a history of prenatal opioid exposure. How prenatal opioid exposure affects pain sensitivity in offspring is of interest, as this may perpetuate the opioid epidemic. While few studies ha...
Heterogeneous associations of gut microbiota with Crohn's disease activity [0.03%]
胃肠道微生物与克罗恩病活动度的异质性关联研究
Susanne Pinto,Elisa Benincà,Gianluca Galazzo et al.
Susanne Pinto et al.
The multi-factorial involvement of gut microbiota with Crohn's disease (CD) necessitates robust analysis to uncover possible associations with particular microbes. CD has been linked to specific bacteria, but reported associations vary wide...
Impact of glyphosate (RoundupTM) on the composition and functionality of the gut microbiome [0.03%]
草甘膦（Roundup）对肠道微生物组组成和功能的影响
Lauren Walsh,Colin Hill,R Paul Ross
Lauren Walsh
Glyphosate, the active ingredient in the broad-spectrum herbicide RoundupTM, has been a topic of discussion for decades due to contradictory reports of the effect of glyphosate on human health. Glyphosate inhibits the enzyme 5-enolpyruvylsh...
The impact of aging-induced gut microbiome dysbiosis on dendritic cells and lung diseases [0.03%]
衰老引起的肠道菌群失调对树突状细胞和肺部疾病的影响
Jonaid Ahmad Malik,Mohammad Adeel Zafar,Taruna Lamba et al.
Jonaid Ahmad Malik et al.
Aging is an inevitable natural process that impacts every individual, and understanding its effect on the gut microbiome and dendritic cell (DC) functionality in elderly subjects is crucial. DCs are vital antigen-presenting cells (APCs) tha...
Akkermansia muciniphila protects the intestine from irradiation-induced injury by secretion of propionic acid [0.03%]
Akkermansia muciniphila通过分泌丙酸保护肠道免受放射损伤
Kai-Yue He,Xin-Yuan Lei,Dan-Hui Wu et al.
Kai-Yue He et al.
Intestinal dysbiosis frequently occurs in abdominal radiotherapy and contributes to irradiation (IR)-induced intestinal damage and inflammation. Akkermansia muciniphila (A. muciniphila) is a recently characterized probiotic, which is critic...
Butyrate reduces adherent-invasive E. coli-evoked disruption of epithelial mitochondrial morphology and barrier function: involvement of free fatty acid receptor 3 [0.03%]
丁酸通过游离脂肪酸受体3减少肠道上皮细胞线粒体形态紊乱及黏附侵袭性大肠杆菌导致的屏障功能障碍
Samira A Hamed,Armaan Mohan,Saranya Navaneetha Krishnan et al.
Samira A Hamed et al.
Gut bacteria provide benefits to the host and have been implicated in inflammatory bowel disease (IBD), where adherent-invasive E. coli (AIEC) pathobionts (e.g., strain LF82) are associated with Crohn's disease. E. coli-LF82 causes fragment...
Targeting gut microbiota in aging-related cardiovascular dysfunction: focus on the mechanisms [0.03%]
针对与衰老相关的心血管功能障碍的肠道菌群靶向：聚焦其机制研究
Siqi Liu,Yufeng He,Yali Zhang et al.
Siqi Liu et al.
The global population is aging and age-related cardiovascular disease is increasing. Even after controlling for cardiovascular risk factors, readmission and mortality rates remain high. In recent years, more and more in-depth studies have f...
Metaproteomic assessment of gut microbial and host functional perturbations in Helicobacter pylori-infected patients subjected to an antimicrobial protocol [0.03%]
基于抗微生物方案对幽门螺旋杆菌感染患者进行的元蛋白质组评估肠道微生物及宿主功能变化研究
Marcello Abbondio,Alessandro Tanca,Laura De Diego et al.
Marcello Abbondio et al.
The impact of therapeutic interventions on the human gut microbiota (GM) is a clinical issue of paramount interest given the strong interconnection between microbial dynamics and human health. Orally administered antibiotics are known to re...