Feiling Huang,Ying Cao,Jinghui Liang et al.
Feiling Huang et al.
Ovarian aging occurs prior to the aging of other organ systems and acts as the pacemaker of the aging process of multiple organs. As life expectancy has increased, preventing ovarian aging has become an essential goal for promoting extended...
Ashwin Chetty,Ran Blekhman
Ashwin Chetty
The gut microbiome interacts with the host through complex networks that affect physiology and health outcomes. It is becoming clear that these interactions can be measured across many different omics layers, including the genome, transcrip...
Hyperbaric oxygen augments susceptibility to C. difficile infection by impairing gut microbiota ability to stimulate the HIF-1α-IL-22 axis in ILC3 [0.03%]
高压氧通过损害肠道微生物刺激ILC3中HIF-1α-IL-22轴的能力增强对艰难梭菌感染的易感性
José L Fachi,Laís P Pral,Helder C Assis et al.
José L Fachi et al.
Hyperbaric oxygen (HBO) therapy is a well-established method for improving tissue oxygenation and is typically used for the treatment of various inflammatory conditions, including infectious diseases. However, its effect on the intestinal m...
DSS treatment does not affect murine colonic microbiota in absence of the host [0.03%]
在没有宿主的情况下,DSS治疗不会影响小鼠结肠微生物群
Jannike Lea Krause,Beatrice Engelmann,Stephanie Serena Schaepe et al.
Jannike Lea Krause et al.
The prevalence of inflammatory bowel disease (IBD) is rising globally; however, its etiology is still not fully understood. Patient genetics, immune system, and intestinal microbiota are considered critical factors contributing to IBD. Prec...
Gut microbiome responds to alteration in female sex hormone status and exacerbates metabolic dysfunction [0.03%]
女性性激素水平变化会影响肠道菌群并加重代谢功能障碍
Tzu-Wen L Cross,Abigayle M R Simpson,Ching-Yen Lin et al.
Tzu-Wen L Cross et al.
Women are at significantly greater risk of metabolic dysfunction after menopause, which subsequently leads to numerous chronic illnesses. The gut microbiome is associated with obesity and metabolic dysfunction, but its interaction with fema...
Microbial collaborations and conflicts: unraveling interactions in the gut ecosystem [0.03%]
微生物的协作与冲突：解析肠道生态系统中的相互作用
Shuang Wang,Lingyi Mu,Chong Yu et al.
Shuang Wang et al.
The human gut microbiota constitutes a vast and complex community of microorganisms. The myriad of microorganisms present in the intestinal tract exhibits highly intricate interactions, which play a crucial role in maintaining the stability...
Colicins and T6SS-based competition systems enhance enterotoxigenic E. coli (ETEC) competitiveness [0.03%]
肠毒素性大肠杆菌（ETEC）的竞争优势得益于科利菌素和T6SS系统
Jonas Kjellin,Danna Lee,Hans Steinsland et al.
Jonas Kjellin et al.
Diarrheal diseases are still a significant problem for humankind, causing approximately half a million deaths annually. To cause diarrhea, enteric bacterial pathogens must first colonize the gut, which is a niche occupied by the normal bact...
Fusobacterium nucleatum promotes inflammatory and anti-apoptotic responses in colorectal cancer cells via ADP-heptose release and ALPK1/TIFA axis activation [0.03%]
中间普氏菌通过ADP-庚糖释放和ALPK1/TIFA轴激活促进结肠直肠癌细胞的炎症和抗凋亡反应
Camille Martin-Gallausiaux,Laurène Salesse,Diego Garcia-Weber et al.
Camille Martin-Gallausiaux et al.
The anaerobic bacterium Fusobacterium nucleatum is significantly associated with human colorectal cancer (CRC) and is considered a significant contributor to the disease. The mechanisms underlying the promotion of intestinal tumor formation...
Precocious infant fecal microbiome promotes enterocyte barrier dysfuction, altered neuroendocrine signaling and associates with increased childhood obesity risk [0.03%]
早发的婴儿粪便微生物组促进肠上皮屏障功能障碍，改变神经内分泌信号并增加儿童肥胖的风险
Germaine J M Yong,Cara E Porsche,Alexandra R Sitarik et al.
Germaine J M Yong et al.
Early life gut microbiome composition has been correlated with childhood obesity, though microbial functional contributions to disease origins remain unclear. Here, using an infant birth cohort (n = 349) we identify a distinct fecal microbi...
The impact of gut microbiome enterotypes on ulcerative colitis: identifying key bacterial species and revealing species co-occurrence networks using machine learning [0.03%]
肠道微生物群类型对溃疡性结肠炎的影响：利用机器学习识别关键细菌种类并揭示物种共发生网络
Xuangao Wu,Ting Zhang,TianShun Zhang et al.
Xuangao Wu et al.
Ulcerative colitis (UC) is a chronic inflammatory intestinal disease affecting the colon and rectum, with its pathogenesis attributed to genetic background, environmental factors, and gut microbes. This study aimed to investigate the role o...