Microbiota and mucosal gene expression of fecal microbiota transplantation or placebo treated patients with chronic pouchitis [0.03%]
粪菌移植或假药治疗慢性贮袋炎患者微生物群和黏膜基因表达的变化
Anna K Hartikainen,Imran Khan,Essi K Karjalainen et al.
Anna K Hartikainen et al.
Altered microbiota and impaired host immune function have been linked to the pathogenesis of pouchitis. We used 16S rRNA gene sequencing and RNA sequencing data from a previous randomized clinical trial (RCT) on fecal microbiota transplanta...
Gut microbiome-derived butyrate inhibits the immunosuppressive factors PD-L1 and IL-10 in tumor-associated macrophages in gastric cancer [0.03%]
胃癌相关的巨噬细胞中，来自肠道微生物群的丁酸盐抑制免疫抑制因子PD-L1和IL-10
Seung Yoon Lee,JooYeon Jhun,Jin Seok Woo et al.
Seung Yoon Lee et al.
Early detection and surgical treatment are essential to achieve a good outcome in gastric cancer (GC). Stage IV and recurrent GC have a poor prognosis. Therefore, new treatments for GC are needed. We investigated the intestinal microbiome o...
Daily skin-to-skin contact alters microbiota development in healthy full-term infants [0.03%]
每日的皮肤接触改变健康足月婴儿的微生物群落发育
Henrik Andreas Eckermann,Jennifer Meijer,Kelly Cooijmans et al.
Henrik Andreas Eckermann et al.
The gut microbiota is vital for human body development and function. Its development in early life is influenced by various environmental factors. In this randomized controlled trial, the gut microbiota was obtained as a secondary outcome m...
Randomized Controlled Trial
Gut microbes. 2024 Jan-Dec;16(1):2295403. DOI:10.1080/19490976.2023.2295403 2024
Prophylactic treatment with Bacteroides uniformis and Bifidobacterium bifidum counteracts hepatic NK cell immune tolerance in nonalcoholic steatohepatitis induced by high fat diet [0.03%]
Bacteroides uniformis和Bifidobacterium bifidum的预防性治疗可抵抗高脂饮食诱导的非酒精性脂肪肝炎中的肝脏NK细胞免疫耐受
Jingyuan Xu,Qiaoyun Xia,Ting Wu et al.
Jingyuan Xu et al.
Hepatic immunity is one of the driving forces for the development of nonalcoholic steatohepatitis (NASH), and targeting gut microbiota is believed to affect the hepatic immune constitution. Here, we aimed to investigate the hepatic immunolo...
Cryptosporidium infection of human small intestinal epithelial cells induces type III interferon and impairs infectivity of Rotavirus [0.03%]
人类小肠上皮细胞的隐孢子虫感染诱导III型干扰素并削弱轮状病毒的感染力
Valentin Greigert,Iti Saraav,Juhee Son et al.
Valentin Greigert et al.
Cryptosporidiosis is a major cause of severe diarrheal disease in infants from resource poor settings. The majority of infections are caused by the human-specific pathogen C. hominis and absence of in vitro growth platforms has limited our ...
Collinsella aerofaciens as a predictive marker of response to probiotic treatment in non-constipated irritable bowel syndrome [0.03%]
Collinsella aerofaciens作为非便秘型肠易激综合症益生菌治疗反应的预测标志物
Giorgio Gargari,Giacomo Mantegazza,Cesare Cremon et al.
Giorgio Gargari et al.
Probiotics are exploited for adjuvant treatment in IBS, but reliable guidance for selecting the appropriate probiotic to adopt for different forms of IBS is lacking. We aimed to identify markers for recognizing non-constipated (NC) IBS pati...
Randomized Controlled Trial
Gut microbes. 2024 Jan-Dec;16(1):2298246. DOI:10.1080/19490976.2023.2298246 2024
Isolation and characterization of a novel lytic Parabacteroides distasonis bacteriophage φPDS1 from the human gut [0.03%]
来自人体肠道的一种新型溶原性Parabacteroides distasonis噬菌体φPDS1的分离与鉴定
Adrián Cortés-Martín,Rémi Denise,Emma Guerin et al.
Adrián Cortés-Martín et al.
The human gut microbiome plays a significant role in health and disease. The viral component (virome) is predominantly composed of bacteriophages (phages) and has received significantly less attention in comparison to the bacteriome. This k...
Yuan-Wei Zhang,Pei-Ran Song,Si-Cheng Wang et al.
Yuan-Wei Zhang et al.
Osteoporosis is a systemic skeletal disease that seriously endangers the health of middle-aged and older adults. Recently, with the continuous deepening of research, an increasing number of studies have revealed gut microbiota as a potentia...
Elucidating the role of diet in maintaining gut health to reduce the risk of obesity, cardiovascular and other age-related inflammatory diseases: recent challenges and future recommendations [0.03%]
饮食在维护肠道健康以降低肥胖、心血管和其它年龄相关炎症性疾病风险中的作用：最近的挑战与未来建议
Tariq Aziz,Nageen Hussain,Zunaira Hameed et al.
Tariq Aziz et al.
A healthy balanced diet is crucial in protecting the immune system against infections and diseases. Poor diets, such as the Western diet, contribute to the development of metabolic diseases, hypertension, and obesity. Microbiota, primarily ...
Pasteurized akkermansia muciniphila improves irritable bowel syndrome-like symptoms and related behavioral disorders in mice [0.03%]
巴氏杀菌的Akkermansia muciniphila改善类似肠易激综合症和相关的行为障碍的小鼠症状
Maëva Meynier,Valentine Daugey,Geoffroy Mallaret et al.
Maëva Meynier et al.
Gut - brain communications disorders in irritable bowel syndrome (IBS) are associated with intestinal microbiota composition, increased gut permeability, and psychosocial disturbances. Symptoms of IBS are difficult to medicate, and hence mu...