Dietary resistant starch supplementation increases gut luminal deoxycholic acid abundance in mice [0.03%]
膳食抗性淀粉补充剂增加小鼠肠道胆酸丰度
Melanie A Reuter,Madelynn Tucker,Zara Marfori et al.
Melanie A Reuter et al.
Bile acids (BA) are among the most abundant metabolites produced by the gut microbiome. Primary BAs produced in the liver are converted by gut bacterial 7-α-dehydroxylation into secondary BAs, which can differentially regulate host health ...
Colibactin-producing Escherichia coli enhance resistance to chemotherapeutic drugs by promoting epithelial to mesenchymal transition and cancer stem cell emergence [0.03%]
产生类大肠杆菌通过促进上皮间充质转化和癌症干细胞的出现来增强对化疗药物的抵抗力
Guillaume Dalmasso,Antony Cougnoux,Tiphanie Faïs et al.
Guillaume Dalmasso et al.
Human colorectal cancers (CRCs) are readily colonized by colibactin-producing E. coli (CoPEC). CoPEC induces DNA double-strand breaks, DNA mutations, genomic instability, and cellular senescence. Infected cells produce a senescence-associat...
Probiotic Lactobacillus spp. improves Drosophila memory by increasing lactate dehydrogenase levels in the brain mushroom body neurons [0.03%]
益生菌乳酸杆菌通过提高果蝇蘑菇体神经元中的乳酸脱氢酶水平来改善其记忆能力
Shuk-Man Ho,Wan-Hua Tsai,Chih-Ho Lai et al.
Shuk-Man Ho et al.
Probiotics are live microorganisms that offer potential benefits to their hosts and can occasionally influence behavioral responses. However, the detailed mechanisms by which probiotics affect the behavior of their hosts and the underlying ...
Gut enterotype-dependent modulation of gut microbiota and their metabolism in response to xanthohumol supplementation in healthy adults [0.03%]
健康成人补充黄花素后其肠道微生物及其代谢物随肠道类型不同而变化的的研究
Paige E Jamieson,Eli B Smart,John A Bouranis et al.
Paige E Jamieson et al.
Xanthohumol (XN), a polyphenol found in the hop plant (Humulus lupulus), has antioxidant, anti-inflammatory, prebiotic, and anti-hyperlipidemic activity. Preclinical evidence suggests the gut microbiome is essential in mediating these bioac...
Randomized Controlled Trial
Gut microbes. 2024 Jan-Dec;16(1):2315633. DOI:10.1080/19490976.2024.2315633 2024
Salmonella enterica serovar Typhimurium remodels mitochondrial dynamics of macrophages via the T3SS effector SipA to promote intracellular proliferation [0.03%]
伤寒沙门氏菌通过T3SS效应物SipA重塑巨噬细胞的线粒体动态以促进胞内增殖
Xingmei Liu,Yutao Liu,Xinyu Zhao et al.
Xingmei Liu et al.
Mitochondrial dynamics are critical in cellular energy production, metabolism, apoptosis, and immune responses. Pathogenic bacteria have evolved sophisticated mechanisms to manipulate host cells' mitochondrial functions, facilitating their ...
From a hunger-regulating hormone to an antimicrobial peptide: gastrointestinal derived circulating endocrine hormone-peptide YY exerts exocrine antimicrobial effects against selective gut microbiota [0.03%]
从调节饥饿的荷尔蒙到抗菌肽：胃肠道衍生的循环内分泌激素-Y肽对选择性的肠道微生物发挥外分泌抗菌作用
Yuchen Xiao,Lingjing Jin,Chao Zhang
Yuchen Xiao
Gut microbiota regulates host melatonin production through epithelial cell MyD88 [0.03%]
肠道菌群通过上皮细胞的MyD88调节宿主褪黑素的生成
Bingnan Liu,Lijuan Fan,Youxia Wang et al.
Bingnan Liu et al.
Melatonin has various physiological effects, such as the maintenance of circadian rhythms, anti-inflammatory functions, and regulation of intestinal barriers. The regulatory functions of melatonin in gut microbiota remodeling have also been...
Gut microbiota-derived trimethylamine N-Oxide: a novel target for the treatment of preeclampsia [0.03%]
肠道菌群衍生的三甲胺氮氧化物：治疗先兆子痫的新靶点
Jiayi Wang,Yajie Gao,Shuaijun Ren et al.
Jiayi Wang et al.
Pre-eclampsia (PE) is the most common complication of pregnancy and seriously threatens the health and safety of the mother and child. Studies have shown that an imbalance in gut microbiota can affect the progression of PE. Trimethylamine N...
Weizmannia coagulans BCF-01: a novel gastrogenic probiotic for Helicobacter pylori infection control [0.03%]
Weizmannia coagulans BCF-01：一种新型的可用于控制幽门螺旋杆菌感染的益生菌
Zhenhui Chen,Ziyu Tang,Wendan Li et al.
Zhenhui Chen et al.
The widespread prevalence of Helicobacter pylori infection, particularly in China, contributes to the development of gastrointestinal diseases. Antibiotics have limitations, including adverse reactions and increased antibiotic resistance. T...
Vancomycin relieves tacrolimus-induced hyperglycemia by eliminating gut bacterial beta-glucuronidase enzyme activity [0.03%]
万古霉素通过消除肠道细菌的β-葡萄糖醛酸酶活性来缓解他克莫司诱导的高血糖
Peixia Li,Rui Zhang,Jinping Zhou et al.
Peixia Li et al.
Up to 40% of transplant recipients treated long-term with tacrolimus (TAC) develop post-transplant diabetes mellitus (PTDM). TAC is an important risk factor for PTDM, but is also essential for immunosuppression after transplantation. Long-t...