Using a human colonoid-derived monolayer to study bacteriophage translocation [0.03%]
用人源结肠类器官单层细胞研究噬菌体的穿入现象
Huu Thanh Le,Alicia Fajardo Lubian,Bethany Bowring et al.
Huu Thanh Le et al.
Bacteriophages (phages) are estimated to be the most abundant microorganisms on Earth. Their presence in human blood suggests that they can translocate from non-sterile sites such as the gastrointestinal tract where they are concentrated. T...
mNFE: microbiome network flow entropy for detecting pre-disease states of type 1 diabetes [0.03%]
基于糖尿病前疾病的微生物组网络流量熵检测方法
Rong Gao,Peiluan Li,Yueqiong Ni et al.
Rong Gao et al.
In the development of Type 1 diabetes (T1D), there are critical states just before drastic changes, and identifying these pre-disease states may predict T1D or provide crucial early-warning signals. Unlike gene expression data, gut microbio...
Breaking the barriers: the role of gut homeostasis in Metabolic-Associated Steatotic Liver Disease (MASLD) [0.03%]
突破壁垒：肠道稳态在代谢相关脂肪性肝病中的作用
Raquel Benedé-Ubieto,Francisco Javier Cubero,Yulia A Nevzorova
Raquel Benedé-Ubieto
Obesity, insulin resistance (IR), and the gut microbiome intricately interplay in Metabolic-associated Steatotic Liver Disease (MASLD), previously known as Non-Alcoholic Fatty Liver Disease (NAFLD), a growing health concern. The complex pro...
CobB-mediated deacetylation of the chaperone CesA regulates Escherichia coli O157:H7 virulence [0.03%]
调节埃希氏大肠杆菌O157:H7毒力的分子伴侣CesA去乙酰化作用机制研究
Linxing Li,Bin Yang,Jing Wang et al.
Linxing Li et al.
Enterohemorrhagic Escherichia coli (EHEC) O157:H7 is a common food-borne pathogen that can cause acute diseases. Lysine acetylation is a post-translational modification (PTM) that occurs in various prokaryotes and is regulated by CobB, the ...
Eléonore Beurel
Eléonore Beurel
The gut microbiota exerts a mutualistic interaction with the host in a fragile ecosystem and the host intestinal, neural, and immune cells. Perturbations of the gastrointestinal track composition after stress have profound consequences on t...
Unveiling the hidden players: exploring the role of gut mycobiome in cancer development and treatment dynamics [0.03%]
揭开隐藏的参与者：探究肠道真菌群在癌症发生及治疗中的作用动态
Lingxi Li,Xiaowen Huang,Haoyan Chen
Lingxi Li
The role of gut fungal species in tumor-related processes remains largely unexplored, with most studies still focusing on fungal infections. This review examines the accumulating evidence suggesting the involvement of commensal and pathogen...
Correction [0.03%]
更正
Published Erratum
Gut microbes. 2024 Jan-Dec;16(1):2329383. DOI:10.1080/19490976.2024.2329383 2024
Long- and short-term effects of fecal microbiota transplantation on antibiotic resistance genes: results from a randomized placebo-controlled trial [0.03%]
粪便微生物移植对耐药基因的长期及短期影响——一项随机对照试验的结果
Armin Rashidi,Maryam Ebadi,Tauseef Ur Rehman et al.
Armin Rashidi et al.
In small series, third-party fecal microbiota transplantation (FMT) has been successful in decolonizing the gut from clinically relevant antibiotic resistance genes (ARGs). Less is known about the short- and long-term effects of FMT on larg...
Randomized Controlled Trial
Gut microbes. 2024 Jan-Dec;16(1):2327442. DOI:10.1080/19490976.2024.2327442 2024
ZntA maintains zinc and cadmium homeostasis and promotes oxidative stress resistance and virulence in Vibrio parahaemolyticus [0.03%]
ZntA在副溶血弧菌中维持锌和镉稳态并促进氧化压力抵抗和毒力
Chengkun Zheng,Yimeng Zhai,Jun Qiu et al.
Chengkun Zheng et al.
Although metals are essential for life, they are toxic to bacteria in excessive amounts. Therefore, the maintenance of metal homeostasis is critical for bacterial physiology and pathogenesis. Vibrio parahaemolyticus is a significant food-bo...
BaiJ and BaiB are key enzymes in the chenodeoxycholic acid 7α-dehydroxylation pathway in the gut microbe Clostridium scindens ATCC 35704 [0.03%]
BaiJ和BaiB是肠道微生物Clostridium scindens ATCC 35704中胆经销酸7α-脱氢化途径中的关键酶
Karin Lederballe Meibom,Solenne Marion,Colin Volet et al.
Karin Lederballe Meibom et al.
Bile acid transformation is a common gut microbiome activity that produces secondary bile acids, some of which are important for human health. One such process, 7α-dehydroxylation, converts the primary bile acids, cholic acid and chenodeox...