Dietary fiber guar gum-induced shift in gut microbiota metabolism and intestinal immune activity enhances susceptibility to colonic inflammation [0.03%]
饮食中的瓜尔胶诱导肠道菌群代谢和肠免疫活性的变化从而增强结肠炎的易感性
Devendra Paudel,Divek V T Nair,Sangshan Tian et al.
Devendra Paudel et al.
With an increasing interest in dietary fibers (DFs) to promote intestinal health and the growth of beneficial gut bacteria, there is a continued rise in the incorporation of refined DFs in processed foods. It is still unclear how refined fi...
A randomized double-blind, placebo-controlled trial to evaluate the safety and efficacy of live Bifidobacterium longum CECT 7347 (ES1) and heat-treated Bifidobacterium longum CECT 7347 (HT-ES1) in participants with diarrhea-predominant irritable bowel syndrome [0.03%]
一项随机双盲安慰剂对照试验：评估长双歧杆菌CECT 7347（ES1）活菌和热灭活长双歧杆菌CECT 7347（HT-ES1）治疗腹泻型肠易激综合征患者的安全性和有效性
S Srivastava,U Basak,M Naghibi et al.
S Srivastava et al.
To determine the efficacy of the probiotic Bifidobacterium longum CECT 7347 (ES1) and postbiotic heat-treated Bifidobacterium longum CECT 7347 (HT-ES1) in improving symptom severity in adults with diarrhea-predominant irritable bowel syndro...
Randomized Controlled Trial
Gut microbes. 2024 Jan-Dec;16(1):2338322. DOI:10.1080/19490976.2024.2338322 2024
Sialic acid-based probiotic intervention in lactating mothers improves the neonatal gut microbiota and immune responses by regulating sialylated milk oligosaccharide synthesis via the gut-breast axis [0.03%]
乳母岩藻糖基化益生菌干预通过调节“肠道-乳汁轴”介导的唾液酸乳寡糖合成改善新生儿肠道微生物和免疫反应
Yushuang Wang,Binqi Rui,Xiaolei Ze et al.
Yushuang Wang et al.
Human milk oligosaccharides (HMOs) are vital milk carbohydrates that help promote the microbiota-dependent growth and immunity of infants. Sialic acid (SA) is a crucial component of sialylated milk oligosaccharides (S-MOs); however, the eff...
Effects of Prevotella copri on insulin, gut microbiota and bile acids [0.03%]
Prevotella copri对胰岛素、肠道菌群和胆汁酸的影响
Jiatai Gong,Qianjin Zhang,Ruizhi Hu et al.
Jiatai Gong et al.
Obesity is becoming a major global health problem in children that can cause diseases such as type 2 diabetes and metabolic disorders, which are closely related to the gut microbiota. However, the underlying mechanism remains unclear. In th...
A high fiber diet or supplementation with Lactococcus lactis subspecies cremoris to pregnant mice confers protection against intestinal injury in adult offspring [0.03%]
高纤维饮食或乳酸克鲁维酵母亚种乳脂株补充可使小鼠后代成年后免受肠道损伤
Maria E Barbian,Joshua A Owens,Crystal R Naudin et al.
Maria E Barbian et al.
The diet during pregnancy, or antenatal diet, influences the offspring's intestinal health. We previously showed that antenatal butyrate supplementation reduces injury in adult murine offspring with dextran sulfate sodium (DSS)-induced coli...
Multi-strain probiotics during pregnancy in women with obesity influence infant gut microbiome development: results from a randomized, double-blind placebo-controlled study [0.03%]
多菌株益生菌对肥胖孕妇的婴儿肠道微生物群发育的影响：一项随机、双盲、安慰剂对照研究的结果
Sofie Ingdam Halkjær,Malene Refslund Danielsen,Victoria E de Knegt et al.
Sofie Ingdam Halkjær et al.
Probiotics have been described to influence host health and prevent the risk of obesity by gut microbiome (GM) modulation. In a randomized double-blinded placebo-controlled feasibility study, we investigated whether Vivomixx® multi-strain ...
Randomized Controlled Trial
Gut microbes. 2024 Jan-Dec;16(1):2337968. DOI:10.1080/19490976.2024.2337968 2024
New treatment approaches for Clostridioides difficile infections: alternatives to antibiotics and fecal microbiota transplantation [0.03%]
难辨梭菌感染的新型治疗策略：抗生素和粪便微生物群移植之外的疗法
Tomaž Bratkovič,Abida Zahirović,Maruša Bizjak et al.
Tomaž Bratkovič et al.
Clostridioides difficile causes a range of debilitating intestinal symptoms that may be fatal. It is particularly problematic as a hospital-acquired infection, causing significant costs to the health care system. Antibiotics, such as vancom...
Cognitive behavioral and mindfulness with daily exercise intervention is associated with changes in intestinal microbial taxa and systemic inflammation in patients with Crohn's disease [0.03%]
认知行为和正念结合日常锻炼干预与克罗恩病患者的肠道微生物群分类和全身性炎症变化有关
Ilan K,Motro Y,Nemirovsky A et al.
Ilan K et al.
Crohn's disease (CD) is a chronic inflammatory bowel disease associated with psychological distress and intestinal microbial changes. Here, we examined whether a 3-month period of Cognitive Behavioral and Mindfulness with Daily Exercise (CO...
Gastrointestinal microbiota and metabolites possibly contribute to distinct pathogenicity of SARS-CoV-2 proto or its variants in rhesus monkeys [0.03%]
肠道微生物群和代谢物可能有助于SARS-CoV-2原型或其变异体在食蟹猴中的不同致病性
Hongyu Chen,Junbin Wang,Kaiyun Ding et al.
Hongyu Chen et al.
Gastrointestinal (GI) infection is evidenced with involvement in COVID-19 pathogenesis caused by SARS-CoV-2. However, the correlation between GI microbiota and the distinct pathogenicity of SARS-CoV-2 Proto and its emerging variants remains...
Integrative analysis with microbial modelling and machine learning uncovers potential alleviators for ulcerative colitis [0.03%]
整合微生物建模和机器学习的综合分析发现溃疡性结肠炎潜在的缓解因子
Jinlin Zhu,Jialin Yin,Jing Chen et al.
Jinlin Zhu et al.
Ulcerative colitis (UC) is a challenging form of inflammatory bowel disease, and its etiology is intricately linked to disturbances in the gut microbiome. To identify the potential alleviators of UC, we employed an integrative analysis comb...