M2 macrophages participate in ILC2 activation induced by Helicobacter pylori infection [0.03%]
Helicobacter pylori感染诱导的ILC2活化中有M2型巨噬细胞的参与
Ruyi Peng,Canxia Xu,Linfang Zhang et al.
Ruyi Peng et al.
Helicobacter pylori (H. pylori) causes a diversity of gastric diseases. The host immune response evoked by H. pylori infection is complicated and can influence the development and progression of diseases. We have reported that the Group 2 i...
Sweet, bloody consumption - what we eat and how it affects vascular ageing, the BBB and kidney health in CKD [0.03%]
甜蜜而残酷的消耗——我们的饮食及其对血管老化、血脑屏障和慢性肾脏病患者肾健康的影响
Angelina Schwarz,Leah Hernandez,Samsul Arefin et al.
Angelina Schwarz et al.
In today's industrialized society food consumption has changed immensely toward heightened red meat intake and use of artificial sweeteners instead of grains and vegetables or sugar, respectively. These dietary changes affect public health ...
Efficacy of an inulin-based treatment on intestinal colonization by multidrug-resistant E. coli: insight into the mechanism of action [0.03%]
益生元布拉氏酵母菌和鼠李糖乳杆菌抑制多药耐药大肠埃希氏菌定植：作用机制研究
Murad Ishnaiwer,Quentin Le Bastard,Maxime Naour et al.
Murad Ishnaiwer et al.
Inulin, an increasingly studied dietary fiber, alters intestinal microbiota. The aim of this study was to assess whether inulin decreases intestinal colonization by multidrug resistant E. coli and to investigate its potential mechanisms of ...
Recipient microbiome-related features predicting metabolic improvement following fecal microbiota transplantation in adults with severe obesity and metabolic syndrome: a secondary analysis of a phase 2 clinical trial [0.03%]
接受者微生物组相关特征预测重度肥胖和代谢综合征成人患者粪便菌群移植术后代谢改善：一项二期临床试验的事后分析
Zhengxiao Zhang,Valentin Mocanu,Edward C Deehan et al.
Zhengxiao Zhang et al.
Microbial-based therapeutics in clinical practice are of considerable interest, and a recent study demonstrated fecal microbial transplantation (FMT) followed by dietary fiber supplements improved glucose homeostasis. Previous evidence sugg...
Clinical Trial
Gut microbes. 2024 Jan-Dec;16(1):2345134. DOI:10.1080/19490976.2024.2345134 2024
Bacterial membrane vesicles in the pathogenesis and treatment of inflammatory bowel disease [0.03%]
细菌膜囊泡在炎症性肠病发病机制和治疗中的作用
Chinasa Valerie Olovo,Dickson Kofi Wiredu Ocansey,Ying Ji et al.
Chinasa Valerie Olovo et al.
Inflammatory bowel disease (IBD) is a chronic and debilitating condition of relapsing and remitting inflammation in the gastrointestinal tract. Conventional therapeutic approaches for IBD have shown limited efficacy and detrimental side eff...
Genetic and microbial determinants of azoxymethane-induced colorectal tumor susceptibility in Collaborative Cross mice and their implication in human cancer [0.03%]
协同杂交小鼠中azoxymethane诱导的结直肠肿瘤易感性的基因和微生物决定因素及其在人类癌症中的意义
Dan Li,Chenhan Zhong,Mengyuan Yang et al.
Dan Li et al.
The insights into interactions between host genetics and gut microbiome (GM) in colorectal tumor susceptibility (CTS) remains lacking. We used Collaborative Cross mouse population model to identify genetic and microbial determinants of Azox...
Intestinal carbapenem-resistant Klebsiella pneumoniae undergoes complex transcriptional reprogramming following immune activation [0.03%]
免疫激活后肠道碳青霉烯耐药肺炎克雷伯菌转录重塑复杂多样
Clement David,Aleksander Czauderna,Liqing Cheng et al.
Clement David et al.
Carbapenem-resistant Klebsiella pneumoniae (CR-Kp) is a significant threat to public health worldwide. The primary reservoir for CR-Kp is the intestinal tract. There, the bacterium is usually present at low density but can bloom following a...
Prebiotic utilisation provides Lactiplantibacillus plantarum a competitive advantage in vitro, but is not reflected by an increased intestinal fitness [0.03%]
益生菌利用提供Lactiplantibacillus plantarum体外竞争优势，但并未反映其肠道适应性增强
Jori Fuhren,Markus Schwalbe,Jos Boekhorst et al.
Jori Fuhren et al.
Synbiotics combine the concepts of probiotics and prebiotics to synergistically enhance the health-associated effects of both components. Previously, we have shown that the intestinal persistence of inulin-utilizing L. plantarum Lp900 is si...
The gut microbe pair of Oribacterium sp. GMB0313 and Ruminococcus sp. GMB0270 confers complete protection against SARS-CoV-2 infection by activating CD8+ T cell-mediated immunity [0.03%]
奥里巴斯菌GMB0313和鼠伤寒沙门氏菌GMB0270互作通过激活CD8+T细胞介导的免疫反应赋予机体抵御新冠病毒入侵的完全保护力
Mingda Wang,Enkhchimeg Lkhagva,Sura Kim et al.
Mingda Wang et al.
Despite the potential protective role of the gut microbiome against COVID-19, specific microbes conferring resistance to COVID-19 have not yet been identified. In this work, we aimed to identify and validate gut microbes at the species leve...
Proton pump inhibitors increase the risk of carbapenem-resistant Enterobacteriaceae colonization by facilitating the transfer of antibiotic resistance genes among bacteria in the gut microbiome [0.03%]
质子泵抑制剂通过促进肠道菌群中抗生素耐药基因在细菌间的转移来增加碳青霉烯类耐药肠杆菌定植的风险
Imchang Lee,Jae-Won Jo,Heung-Jeong Woo et al.
Imchang Lee et al.
Carbapenem-resistant Enterobacteriaceae (CRE) pose a global health threat; however, there is still limited understanding of the risk factors and underlying mechanisms of CRE colonization in the gut microbiome. We conducted a matched case-co...