Akkermansia muciniphila: a deworming partner independent of type 2 immunity [0.03%]
Akkermansia muciniphila：一种独立于2型免疫的驱虫伙伴
Jiaqi Wang,Xiufeng Zhao,Xianhe Li et al.
Jiaqi Wang et al.
The gut microbiota has coevolved with the host for hundreds of millions of years, playing a beneficial role in host health. Human parasitic helminths are widespread and pose a pervasive global public health issue. Although Type 2 immunity p...
Ethanolamine enhances adhesion, promotes microcompartment formation, and modulates gene expression in Levilactobacillus brevis ATCC 14869 [0.03%]
乙醇胺增强黏附性，促进微室形成并调控Levilactobacillus brevis ATCC 14869的基因表达
Polycronis P Akouris,Gerrit A Stuivenberg,John A Chmiel et al.
Polycronis P Akouris et al.
Ethanolamine is an abundant compound in the gastrointestinal tract and a valuable source of carbon and nitrogen for pathogenic bacteria harboring ethanolamine utilization (eut) genes. Eut-positive pathogens can consume free ethanolamine to ...
Metabolome-associated psychological comorbidities improvement in irritable bowel syndrome patients receiving a probiotic [0.03%]
益生菌治疗肠易激综合征患者代谢组和心理合并症改善
Francois-Pierre Martin,Ornella Cominetti,Bernard Berger et al.
Francois-Pierre Martin et al.
Our recent randomized, placebo-controlled study in Irritable Bowel Syndrome (IBS) patients with diarrhea or alternating bowel habits showed that the probiotic Bifidobacterium longum (BL) NCC3001 improves depression scores and decreases brai...
Randomized Controlled Trial
Gut microbes. 2024 Jan-Dec;16(1):2347715. DOI:10.1080/19490976.2024.2347715 2024
An emerging strategy: probiotics enhance the effectiveness of tumor immunotherapy via mediating the gut microbiome [0.03%]
一种新兴策略：益生菌通过调控肠道菌群增强肿瘤免疫治疗疗效
Shuaiming Jiang,Wenyao Ma,Chenchen Ma et al.
Shuaiming Jiang et al.
The occurrence and progression of tumors are often accompanied by disruptions in the gut microbiota. Inversely, the impact of the gut microbiota on the initiation and progression of cancer is becoming increasingly evident, influencing the t...
Meta-analysis identifying gut microbial biomarkers of Qinghai-Tibet Plateau populations and the functionality of microbiota-derived butyrate in high-altitude adaptation [0.03%]
meta分析识别青藏高原人群的肠道微生物标志物及菌群衍生丁酸盐的高海拔适应功能
Hongwen Zhao,Longjie Sun,Jiali Liu et al.
Hongwen Zhao et al.
The extreme environmental conditions of a plateau seriously threaten human health. The relationship between gut microbiota and human health at high altitudes has been extensively investigated. However, no universal gut microbiota biomarkers...
Meta-Analysis
Gut microbes. 2024 Jan-Dec;16(1):2350151. DOI:10.1080/19490976.2024.2350151 2024
Spatial transcriptomic analysis reveals local effects of intratumoral fusobacterial infection on DNA damage and immune signaling in rectal cancer [0.03%]
空间转录组分析揭示了肠道肿瘤内福斯杆菌感染对DNA损伤和免疫信号的局部影响
William P Duggan,Batuhan Kisakol,Ina Woods et al.
William P Duggan et al.
Mucinous colorectal cancer (CRC) is a common histological subtype of colorectal adenocarcinoma, associated with a poor response to chemoradiotherapy. The commensal facultative anaerobes fusobacteria, have been associated with poor prognosis...
Human gut-associated Bifidobacterium species salvage exogenous indole, a uremic toxin precursor, to synthesize indole-3-lactic acid via tryptophan [0.03%]
人类肠道相关双歧杆菌属物种通过色氨酸途径回收外源性吲哚合成吲哚-3-乳酸
Cheng Chung Yong,Takuma Sakurai,Hiroki Kaneko et al.
Cheng Chung Yong et al.
Indole in the gut is formed from dietary tryptophan by a bacterial tryptophan-indole lyase. Indole not only triggers biofilm formation and antibiotic resistance in gut microbes but also contributes to the progression of kidney dysfunction a...
Commensal microbiota-derived metabolite agmatine triggers inflammation to promote colorectal tumorigenesis [0.03%]
共生微生物衍生的代谢物精胺触发炎症以促进结直肠肿瘤发生
Yu Lu,Aoxi Cui,Xiaobo Zhang
Yu Lu
Colorectal cancer (CRC), a malignant tumor worldwide, is associated with gut microbiota. The influence of gut microbe-derived metabolites on CRC has attracted a lot of attention. However, the role of immunity mediated by commensal microbiot...
Microbiota-derived I3A protects the intestine against radiation injury by activating AhR/IL-10/Wnt signaling and enhancing the abundance of probiotics [0.03%]
微生物衍生的I3A通过激活AhR/IL-10/Wnt信号通路并增加益生菌丰度来保护肠道免受辐射损伤
Li-Wei Xie,Shang Cai,Hai-Yan Lu et al.
Li-Wei Xie et al.
The intestine is prone to radiation damage in patients undergoing radiotherapy for pelvic tumors. However, there are currently no effective drugs available for the prevention or treatment of radiation-induced enteropathy (RIE). In this stud...
Human gut microbiota and their production of endocannabinoid-like mediators are directly affected by a dietary oil [0.03%]
饮食用油直接影响人体肠道菌群及其内源大麻素类似介质的产生
Charlène Roussel,Mathilde Sola,Jacob Lessard-Lord et al.
Charlène Roussel et al.
Dietary omega-3 polyunsaturated fatty acids (n-3 PUFAs) and the gut microbiome affect each other. We investigated the impact of supplementation with Buglossoides arvensis oil (BO), rich in stearidonic acid (SDA), on the human gut microbiome...