Pinaki Panigrahi
Pinaki Panigrahi
The role of gut microbiome in health, a century-old concept, has been on the center stage of medical research recently. While different body sites, disease conditions, and populations have been targeted, neonatal and early infancy appear to...
Spatio-temporal dynamics of the human small intestinal microbiome and its response to a synbiotic [0.03%]
人体小肠微生物组的时空动态及其对合生元的反应
Ran An,Ellen Wilms,Jacoline Gerritsen et al.
Ran An et al.
Although fecal microbiota composition is considered to preserve relevant and representative information for distal colonic content, it is evident that it does not represent microbial communities inhabiting the small intestine. Nevertheless,...
Randomized Controlled Trial
Gut microbes. 2024 Jan-Dec;16(1):2350173. DOI:10.1080/19490976.2024.2350173 2024
Cultivated Enterococcus faecium B6 from children with obesity promotes nonalcoholic fatty liver disease by the bioactive metabolite tyramine [0.03%]
从肥胖儿童中分离的枯草芽孢杆菌B6通过生物活性代谢物酪胺促进非酒精性脂肪肝病
Jia Wei,Jiayou Luo,Fei Yang et al.
Jia Wei et al.
Gut microbiota plays an essential role in nonalcoholic fatty liver disease (NAFLD). However, the contribution of individual bacterial strains and their metabolites to childhood NAFLD pathogenesis remains poorly understood. Herein, the criti...
Prevotella copri promotes vascular calcification via lipopolysaccharide through activation of NF-κB signaling pathway [0.03%]
普雷沃氏菌通过激活NF-κB信号通路促进血管钙化
Qing-Yun Hao,Jing Yan,Jin-Tao Wei et al.
Qing-Yun Hao et al.
Emerging evidence indicates that alteration of gut microbiota plays an important role in chronic kidney disease (CKD)-related vascular calcification (VC). We aimed to investigate the specific gut microbiota and the underlying mechanism invo...
Ecological insights into hematopoiesis regulation: unraveling the influence of gut microbiota [0.03%]
生态视角下的造血调控研究:揭示肠道微生物群的影响
Kaiwen Zheng,Zhifeng Wei,Wei Li
Kaiwen Zheng
The gut microbiota constitutes a vast ecological system within the human body, forming a mutually interdependent entity with the host. In recent years, advancements in molecular biology technologies have provided a clearer understanding of ...
Biofilms and core pathogens shape the tumor microenvironment and immune phenotype in colorectal cancer [0.03%]
结直肠癌中生物膜和核心病原体塑造肿瘤微环境和免疫表型
Lasse Kvich,Blaine Gabriel Fritz,Henrike Zschach et al.
Lasse Kvich et al.
Extensive research has explored the role of gut microbiota in colorectal cancer (CRC). Nonetheless, metatranscriptomic studies investigating the in situ functional implications of host-microbe interactions in CRC are scarce. Therefore, we c...
Diet-microbiota associations in gastrointestinal research: a systematic review [0.03%]
胃肠病学研究中的饮食-微生物组关系:系统性综述
Kerith Duncanson,Georgina Williams,Emily C Hoedt et al.
Kerith Duncanson et al.
Interactions between diet and gastrointestinal microbiota influence health status and outcomes. Evaluating these relationships requires accurate quantification of dietary variables relevant to microbial metabolism, however current dietary a...
Comparison of fidaxomicin, thuricin CD, vancomycin and nisin highlights the narrow spectrum nature of thuricin CD [0.03%]
fidaxomicin、thuricin CD、万古霉素和nisin的比较突出了thuricin CD的窄谱性质
L Walsh,A Lavelle,P M OConnor et al.
L Walsh et al.
Vancomycin and metronidazole are commonly used treatments for Clostridioides difficile infection (CDI). However, these antibiotics have been associated with high levels of relapse in patients. Fidaxomicin is a new treatment for CDI that is ...
Comparative Study
Gut microbes. 2024 Jan-Dec;16(1):2342583. DOI:10.1080/19490976.2024.2342583 2024
Christensenella strain resources, genomic/metabolomic profiling, and association with host at species level [0.03%]
物种水平的Christensenella菌株资源、基因组/代谢组分析及其与宿主的相关性研究
Xin-Wei Sun,Hao-Jie Huang,Xiao-Meng Wang et al.
Xin-Wei Sun et al.
The gut commensal bacteria Christensenellaceae species are negatively associated with many metabolic diseases, and have been seen as promising next-generation probiotics. However, the cultured Christensenellaceae strain resources were limit...
New methods to unveil host-microbe interaction mechanisms along the microbiota-gut-brain-axis [0.03%]
沿菌群-肠-脑轴揭示宿主与微生物互作机制的新方法
Habibullah Moradian,Tristan Gabriel,Mathilde Barrau et al.
Habibullah Moradian et al.
Links between the gut microbiota and human health have been supported throughout numerous studies, such as the development of neurological disease disorders. This link is referred to as the "microbiota-gut-brain axis" and is the focus of an...