Kan Gao,Pu Xiu Wang,Xue Mei et al.
Kan Gao et al.
The gut microbiota has been shown to be associated with a range of illnesses and disorders, including hypertension, which is recognized as the primary factor contributing to the development of serious cardiovascular diseases. In this review...
Hydrogen peroxide in breast milk is crucial for gut microbiota formation and myelin development in neonatal mice [0.03%]
母乳中的过氧化氢对于小鼠新生儿肠道菌群形成和髓鞘发育至关重要
Jun Kambe,Kento Usuda,Ryo Inoue et al.
Jun Kambe et al.
Early life environment influences mammalian brain development, a growing area of research within the Developmental Origins of Health and Disease framework, necessitating a deeper understanding of early life factors on children's brain devel...
Gut-bacteria derived membrane vesicles and host metabolic health: a narrative review [0.03%]
肠道细菌衍生的膜囊泡与宿主代谢健康：综述文章
Jari Verbunt,Johan Jocken,Ellen Blaak et al.
Jari Verbunt et al.
The intestinal microbiota, consisting of an estimated 10^10-10^11 organisms, regulate physiological processes involved in digestion, metabolism, and immunity. Surprisingly, these intestinal microorganisms have been found to influence tissue...
The role of Bifidobacterium genus in modulating the neonate microbiota: implications for antibiotic resistance acquisition in early life [0.03%]
双歧杆菌属在调节新生儿微生物群中的作用及其对生命早期获得抗生素抗性的影响
Anna Samarra,Raúl Cabrera-Rubio,Cecilia Martínez-Costa et al.
Anna Samarra et al.
Resistance to antibiotics in newborns is a huge concern as their immune system is still developing, and infections and resistance acquisition in early life have short- and long-term consequences for their health. Bifidobacterium species are...
The impact of gestational diabetes on functional capacity of the infant gut microbiome is modest and transient [0.03%]
妊娠糖尿病对婴儿肠道微生物组功能能力的影响较小且短暂
Ryan V Chieu,Katharine Hamilton,Paul M Ryan et al.
Ryan V Chieu et al.
Gestational diabetes mellitus (GDM) is a metabolic complication that manifests as hyperglycemia during the later stages of pregnancy. In high resource settings, careful management of GDM limits risk to the pregnancy, and hyperglycemia typic...
The protective role of commensal gut microbes and their metabolites against bacterial pathogens [0.03%]
共生肠道微生物及其代谢物抵御细菌病原体的保护作用
Liqin Cheng,Mário S P Correia,Shawn M Higdon et al.
Liqin Cheng et al.
Multidrug-resistant microorganisms have become a major public health concern around the world. The gut microbiome is a gold mine for bioactive compounds that protect the human body from pathogens. We used a multi-omics approach that integra...
The transplantation of the gut microbiome of fat-1 mice protects against colonic mucus layer disruption and endoplasmic reticulum stress induced by high fat diet [0.03%]
脂肪饮食诱导的肠黏膜损伤和内质网应激的保护作用源于脂肪酸脱氢酶Fat1小鼠肠道菌群的转移
Amina Bourragat,Quentin Escoula,Sandrine Bellenger et al.
Amina Bourragat et al.
High-fat diets alter gut barrier integrity, leading to endotoxemia by impacting epithelial functions and inducing endoplasmic reticulum (ER) stress in intestinal secretory goblet cells. Indeed, ER stress, which is an important contributor t...
Incremental increases in physiological fluid shear progressively alter pathogenic phenotypes and gene expression in multidrug resistant Salmonella [0.03%]
生理流体剪切的增量变化可逐步改变耐多药沙门氏菌的病原性表型和基因表达模式
Jiseon Yang,Jennifer Barrila,Eric A Nauman et al.
Jiseon Yang et al.
The ability of bacteria to sense and respond to mechanical forces has important implications for pathogens during infection, as they experience wide fluid shear fluctuations in the host. However, little is known about how mechanical forces ...
Weiwei Guo,Wei Xiong
Weiwei Guo
The prevalence of eating disorders has been increasing over the last 50 years. Binge eating disorder (BED) and bulimia nervosa (BN) are two typical disabling, costly and life-threatening eating disorders that substantially compromise the ph...
Dietary restriction rescues 5-fluorouracil-induced lethal intestinal toxicity in old mice by blocking translocation of opportunistic pathogens [0.03%]
饮食限制通过阻止机会性病原菌易位拯救5-氟尿嘧啶所致老年小鼠致命的肠道毒性作用
Duozhuang Tang,Rongrong Qiu,Xingxing Qiu et al.
Duozhuang Tang et al.
Chemotherapy remains a major treatment for malignant tumors, yet the application of standard dose intensity chemotherapy is limited due to the side effects of cytotoxic drugs, especially in old populations. The underlying mechanisms of cyto...