Gut microbiota mediates anxiety-like behaviors induced by chronic infection of Toxoplasma gondii in mice [0.03%]
肠道微生物介导慢性感染的小鼠所产生的类似焦虑的行为
Xiaotong Luo,Xiaoying Yang,Shimin Tan et al.
Xiaotong Luo et al.
Background: Chronic infection with the neurotropic parasite Toxoplasma gondii (T. gondii) can cause anxiety and gut microbiota dysbiosis in hosts. However, the potential role of gut microbiota in anxiety induced by the pa...
Age-associated temporal decline in butyrate-producing bacteria plays a key pathogenic role in the onset and progression of neuropathology and memory deficits in 3×Tg-AD mice [0.03%]
与年龄相关的生化短链脂肪酸产生菌的丰度降低在神经病理学和记忆缺陷中起到关键致病作用：3×Tg-AD小鼠模型中的时间性变化研究
Paula M Chilton,Smita S Ghare,Benjamin T Charpentier et al.
Paula M Chilton et al.
Alterations in the gut-microbiome-brain axis are increasingly being recognized to be involved in Alzheimer's disease (AD) pathogenesis. However, the functional consequences of enteric dysbiosis linking gut microbiota and brain pathology in ...
Microbiota-gut-brain axis: interplay between microbiota, barrier function and lymphatic system [0.03%]
微生态-肠-脑轴：微生物、屏障功能与淋巴系统的相互作用
Miaomiao Zhuang,Xun Zhang,Jun Cai
Miaomiao Zhuang
The human gastrointestinal tract, boasting the most diverse microbial community, harbors approximately 100 trillion microorganisms comprising viruses, bacteria, fungi, and archaea. The profound genetic and metabolic capabilities of the gut ...
Fecal virus-like particles are sufficient to reduce necrotizing enterocolitis [0.03%]
粪便病毒样颗粒足以减少坏死性小肠结肠炎
Simone Margaard Offersen,Xiaotian Mao,Malene Roed Spiegelhauer et al.
Simone Margaard Offersen et al.
Fecal filtrate transfer (FFT) is emerging as a safer alternative to traditional fecal microbiota transplantation (FMT) - particularly in the context of necrotizing enterocolitis (NEC), a severe gastrointestinal condition affecting preterm i...
Proteolytic bacteria expansion during colitis amplifies inflammation through cleavage of the external domain of PAR2 [0.03%]
肠道炎期间蛋白酶细菌的扩张通过切割PAR2的外域来放大炎症反应
Liam Emile Rondeau,Bruna Barbosa Da Luz,Alba Santiago et al.
Liam Emile Rondeau et al.
Imbalances in proteolytic activity have been linked to the development of inflammatory bowel diseases (IBD) and experimental colitis. Proteases in the intestine play important roles in maintaining homeostasis, but exposure of mucosal tissue...
Limited predictive value of the gut microbiome and metabolome for response to biological therapy in inflammatory bowel disease [0.03%]
肠道微生物组和代谢组对炎症性肠病生物制剂反应的预测价值有限
Femke M Prins,Iwan J Hidding,Marjolein A Y Klaassen et al.
Femke M Prins et al.
Emerging evidence suggests the gut microbiome's potential in predicting response to biologic treatments in patients with inflammatory bowel disease (IBD). In this prospective study, we aimed to predict treatment response to vedolizumab and ...
Md Rayhan Mahmud,Sanjida Khanam Tamanna,Sharmin Akter et al.
Md Rayhan Mahmud et al.
Phages are the most diversified and dominant members of the gut virobiota. They play a crucial role in shaping the structure and function of the gut microbial community and consequently the health of humans and animals. Phages are found mai...
Machine learning-causal inference based on multi-omics data reveals the association of altered gut bacteria and bile acid metabolism with neonatal jaundice [0.03%]
基于多组学数据的机器学习-因果推理发现肠道菌群和胆汁酸代谢改变与新生儿黄疸相关性
Wanling Chen,Peng Zhang,Xueli Zhang et al.
Wanling Chen et al.
Early identification of neonatal jaundice (NJ) appears to be essential to avoid bilirubin encephalopathy and neurological sequelae. The interaction between gut microbiota and metabolites plays an important role in early life. It is unclear ...
Dietary fiber for the prevention of childhood obesity: a focus on the involvement of the gut microbiota [0.03%]
肠道菌群在儿童肥胖预防中发挥重要作用：膳食纤维的作用
Zhongmin Yang,Mingyue Yang,Edward C Deehan et al.
Zhongmin Yang et al.
Given the worldwide epidemic of overweight and obesity among children, evidence-based dietary recommendations are fundamentally important for obesity prevention. Although the significance of the human gut microbiome in shaping the physiolog...
Disentangle beneficial effects of strain engraftment after fecal microbiota transplantation in subjects with MetSyn [0.03%]
代谢综合征患者粪菌移植后供体菌株定植的有益作用分离研究
Eduard W J van der Vossen,Mark Davids,Bas Voermans et al.
Eduard W J van der Vossen et al.
Fecal Microbiota Transplantation (FMT) has emerged as a potential modality for mitigating microbiome-associated diseases. Despite this potential, the precise causal pathways by which specific gut microbiota strains induce remission remain i...