Circadian rhythms of gut microbiota and plaque vulnerability: mechanisms and chrono-microbiota modulation interventions [0.03%]
肠道微生物昼夜节律与动脉粥样斑块易损性的机制及昼夜节律调节干预措施研究
Taiyu Zhai,Xueyang Zou,Zichen Zhang et al.
Taiyu Zhai et al.
The stability of atherosclerotic plaques constitutes the fundamental pathological basis for acute cardiovascular events, and their circadian rhythm characteristics highlight the essential role of dynamic interactions between the host and mi...
Programmable probiotic consortium employ an oleic acid-inducible system to sense and degrade cholesterol in high-fat diet mice [0.03%]
可编程益生菌联合体利用油酸诱导系统感知和降解高脂饮食小鼠体内胆固醇
Qi Yang,Wei Xiang,Aman Khan et al.
Qi Yang et al.
High cholesterol is a major risk factor for cardiovascular disease (CVD), and current treatment strategies primarily focus on inhibiting cholesterol synthesis and reducing cholesterol absorption. Engineered synthetic consortia are emerging ...
A specifically designed multi-biotic reduces uremic toxin generation and improves kidney function [0.03%]
一种特制的多益生元可减少尿毒症毒素的生成并改善肾功能
Alice Beau,Jane Natividad,Berengère Benoit et al.
Alice Beau et al.
Chronic kidney disease (CKD) is characterized by accumulation of uremic toxins (UTs), such as p-cresyl sulfate and indoxyl sulfate, generated through the transformation of tyrosine and tryptophan by the gut microbiota. Using an ex vivo Simu...
Correction [0.03%]
改正措施
Published Erratum
Gut microbes. 2025 Dec;17(1):2532985. DOI:10.1080/19490976.2025.2532985 2025
SLAMF7 regulates goblet cell mucus production and negatively impacts gut homeostasis and commensalism [0.03%]
SLAMF7调节杯状细胞粘液产生并对肠道稳态和共生关系产生负面影响
Dianrong Zhou,Changbu Wu,Chengjuan Li et al.
Dianrong Zhou et al.
Crosstalk between the intestinal mucosal barrier and the gut microbiota contributes to maintaining intestinal homeostasis. Accumulating evidence suggests that diverse mechanisms are involved in maintaining intestinal homeostasis. Any distur...
The PTPN2 rs1893217 IBD risk allele increases susceptibility to AIEC invasion by a JAK-STAT-CEACAM6 axis [0.03%]
PTPN2(rs1893217) IBD风险等位基因通过JAK-STAT-CEACAM6轴增加AIEC侵袭的倾向性
Pritha Chatterjee,Vinicius Canale,Stephanie J King et al.
Pritha Chatterjee et al.
Inflammatory bowel disease (IBD) patients often exhibit expansion of the gut pathobiont, adherent-invasive E. coli (AIEC). Loss of activity of the IBD susceptibility gene, protein tyrosine phosphatase type 2 (PTPN2), causes gut microbiota d...
Minimal logic gates for probiotic Escherichia coli Nissle 1917 sensing and treatment of dual-bacteria intestinal infection [0.03%]
用于 probiotic 大肠杆菌 Nissle 1917 感知和治疗双菌肠道感染的最小逻辑门电路
Haoran Li,Shanshan Zhang,Jinyan Yin et al.
Haoran Li et al.
Rapid development of synthetic biology has led to engineered probiotics to address the growing concern of infectious diseases and cancer. Dual or multiple bacterial infections are becoming more frequent, but there are few treatment options ...
Current state of microbiota clinical applications in neonatal and pediatric bacterial infections [0.03%]
微生物组的临床应用在新生儿及儿童细菌感染中的作用和挑战
Thanh Thien Le,Tram Ngoc Hoang,Dylan Huy Do et al.
Thanh Thien Le et al.
The microbiota plays a crucial role in pediatric health by shaping immune development and influencing infection susceptibility. In infants and children, an immature microbiota may compromise immune defense, increasing the risk of bacterial ...
Gut microbiota and radiation-induced injury: mechanistic insights and microbial therapies [0.03%]
肠道微生物群和放射损伤：机制见解与微生物疗法
Lili Li,Zian Yang,Yuetao Yi et al.
Lili Li et al.
Radiotherapy represents a crucial therapeutic modality in cancer treatment, yet its efficacy is frequently limited by radiation-induced toxicity. Growing evidence indicates that gut microbiota and their metabolites serve as key regulators o...
Late-onset sepsis treatment in very preterm infants alters longitudinal microbiome trajectory with lower abundance of Bifidobacterium despite probiotic supplementation [0.03%]
极早产婴儿晚期败血症治疗改变了纵向微生物群轨迹，尽管补充了益生菌，但降低了双歧杆菌的丰度
David Brian Healy,Shuo Wang,Dhrati Patangia et al.
David Brian Healy et al.
Introduction: Taxonomic instability within the dynamic gut microbiome of very preterm infants can be associated with various adverse outcomes. This longitudinal study was designed to follow the trajectory of microbiome co...