IL-17 signaling protects against Helicobacter pylori- induced gastric cancer [0.03%]
IL-17信号通过防止幽门螺旋杆菌引起的胃癌发挥保护作用
Lee C Brackman,Matthew S Jung,Emily H Green et al.
Lee C Brackman et al.
Helicobacter pylori infection is the predominant risk factor for the development of gastric cancer. Risk is enhanced by specific H. pylori virulence factors, diet, and the inflammatory response. Chronic activation of T helper (Th) 1 and Th1...
Comparison of Crohn's disease-associated adherent-invasive Escherichia coli (AIEC) from France and Hong Kong: results from the Pacific study [0.03%]
来自法国和香港的克罗恩病相关黏附侵袭性大肠杆菌(AIEC)的对比研究：太平洋地区的研究结果
Caroline Chevarin,Zhilu Xu,Lucas Martin et al.
Caroline Chevarin et al.
Association between ileal colonization by Adherent-Invasive Escherichia coli (AIEC) and Crohn's disease (CD) has been widely described in high-incidence Western countries but remains unexplored in Asian countries with a fast increase in CD ...
Comparative Study
Gut microbes. 2024 Jan-Dec;16(1):2431645. DOI:10.1080/19490976.2024.2431645 2024
Transcriptional profiling of zebrafish intestines identifies macrophages as host cells for human norovirus infection [0.03%]
斑马鱼肠道转录谱分析鉴定出单核细胞是人诺如病毒感染的宿主细胞
Emma Roux,Reegan J Willms,Jana Van Dycke et al.
Emma Roux et al.
Human noroviruses (HuNoVs) are a major cause of diarrheal disease, yet critical aspects of their biology, including cellular tropism, remain unclear. Although research has traditionally focused on the intestinal epithelium, the hypothesis t...
Cerebrovascular damage caused by the gut microbe/host co-metabolite p-cresol sulfate is prevented by blockade of the EGF receptor [0.03%]
肠道微生物/宿主共代谢产物对甲酚硫酸导致的脑血管损伤可通过阻断表皮生长因子受体而预防
Sita N Shah,Tobias B-A Knausenberger,Matthew G Pontifex et al.
Sita N Shah et al.
The gut microbiota-brain axis has been associated with the pathogenesis of numerous disorders, but the mechanism(s) underlying these links are generally poorly understood. Accumulating evidence indicates the involvement of gut microbe-deriv...
Probiotic significance of Lactobacillus strains: a comprehensive review on health impacts, research gaps, and future prospects [0.03%]
乳酸菌菌株的益生菌意义：全面回顾健康影响、研究空白及未来前景
Abdul Bari Shah,Aizhamal Baiseitova,Muhammad Zahoor et al.
Abdul Bari Shah et al.
A rising corpus of research has shown the beneficial effects of probiotic Lactobacilli on human health, contributing to the growing popularity of these microorganisms in recent decades. The gastrointestinal and urinary tracts are home to th...
Human milk oligosaccharides combine with Bifidobacterium longum to form the "golden shield" of the infant intestine: metabolic strategies, health effects, and mechanisms of action [0.03%]
人乳寡糖与长双歧杆菌协同组成婴儿肠道的“金盾”：代谢策略、健康效益及作用机制
Shuo Yang,Junwu Cai,Qian Su et al.
Shuo Yang et al.
Human milk oligosaccharides (HMOs) are the third most important nutrient in human milk and are the gold standard for infant nutrition. Due to the lack of an enzyme system capable of utilizing HMOs in the infant intestine, HMOs cannot be dir...
Butyrate reduces epithelial barrier dysfunction induced by the foodborne mycotoxin deoxynivalenol in cell monolayers derived from pig jejunum organoids [0.03%]
丁酸通过衍生于猪空肠类器官的单层细胞减少由食物中真菌霉素脱氧雪腐镰刀菌烯醇诱导的上皮屏障功能障碍
Julie Alberge,Eloïse Mussard,Carine Al-Ayoubi et al.
Julie Alberge et al.
The foodborne mycotoxin deoxynivalenol (DON) produced by Fusarium species threats animal and human health through disruption of the intestinal barrier. Targeting the gut microbiota and its products appears as a promising strategy to mitigat...
B. vulgatus ameliorates high-fat diet-induced obesity through modulating intestinal serotonin synthesis and lipid absorption in mice [0.03%]
脆弱拟杆菌通过调节小鼠肠道5-HT合成和脂质吸收改善高脂饮食诱导的肥胖症
Xinxin Wen,Xiaoyan Feng,Fang Xin et al.
Xinxin Wen et al.
The consumption of high-fat diets (HFD) and an imbalance in gut microbiome are linked to obesity. However, the intricate connection between them and the underlying mechanisms involved in lipid digestion and absorption remain largely unclear...
Rotavirus rewires host cell metabolic pathways toward glutamine catabolism for effective virus infection [0.03%]
轮状病毒重新连接宿主细胞代谢途径向谷氨酰胺分解代谢以实现有效病毒感染
Suvrotoa Mitra,Ratul Datta Chaudhuri,Rakesh Sarkar et al.
Suvrotoa Mitra et al.
Rotavirus (RV) accounts for 19.11% of global diarrheal deaths. Though GAVI assisted vaccine introduction has curtailed RV induced mortality, factors like RV strain diversity, differential infantile gut microbiome, malnutrition, interference...
More than just a number: the gut microbiota and brain function across the extremes of life [0.03%]
不止一个数字：贯穿一生的肠道微生物群和脑功能
Nathan D Nuzum,Clara Deady,Sarah Kittel-Schneider et al.
Nathan D Nuzum et al.
Understanding the interrelationship between the gut microbiota and host physiology, although still in its relative infancy, has taken important steps forward over the past decade. In the context of brain disorders including those characteri...