Supplier-origin gut microbiomes affect host body weight and select autism-related behaviors [0.03%]
来源自供应商的肠道微生物影响宿主体重和选择孤独症相关行为
Zachary L McAdams,Kevin L Gustafson,Amber L Russell et al.
Zachary L McAdams et al.
Autism spectrum disorders (ASD) are complex human neurodiversities increasing in prevalence within the human population. In search of therapeutics to improve quality-of-life for ASD patients, the gut microbiome (GM) has become a promising t...
Gut microbiota genome features associated with brain injury in extremely premature infants [0.03%]
极早产儿肠道微生物组基因特征与脑损伤的相关性研究
David Seki,Rasmus Kirkegaard,Jay Osvatic et al.
David Seki et al.
Severe brain damage is common among premature infants, and the gut microbiota has been implicated in its pathology. Although the order of colonizing bacteria is well described, the mechanisms underlying aberrant assembly of the gut microbio...
Abnormalities in gut virome signatures linked with cognitive impairment in older adults [0.03%]
肠道病毒组标志异常与老年人认知障碍有关联
Adewale S James,Noorul A Adil,Dayna Goltz et al.
Adewale S James et al.
Multiple emerging lines of evidence indicate that the microbiome contributes to aging and cognitive health. However, the roles of distinct microbial components, such as viruses (virome) and their interactions with bacteria (bacteriome), as ...
The microbiota metabolite, phloroglucinol, confers long-term protection against inflammation [0.03%]
微生物代谢产物海松酚具有长期的抗炎保护作用
Janire Castelo,Sarai Araujo-Aris,Diego Barriales et al.
Janire Castelo et al.
Phloroglucinol is a key byproduct of gut microbial metabolism that has been widely used as a treatment for irritable bowel syndrome. Here, we demonstrate that phloroglucinol tempers macrophage responses to pro-inflammatory pathogens and sti...
The mycobiome as integral part of the gut microbiome: crucial role of symbiotic fungi in health and disease [0.03%]
作为肠道微生物组的组成部分：共生真菌在健康和疾病中的关键作用
Hui Huang,Qiurong Wang,Ying Yang et al.
Hui Huang et al.
The gut mycobiome significantly affects host health and immunity. However, most studies have focused on symbiotic bacteria in the gut microbiome, whereas less attention has been given to symbiotic fungi. Although fungi constitute only 0.01%...
Hypusination in intestinal epithelial cells protects mice from infectious colitis [0.03%]
肠上皮细胞中的Hypusine化保护小鼠免受感染性结肠炎的侵害
Alain P Gobert,Caroline V Hawkins,Kamery J Williams et al.
Alain P Gobert et al.
Enteropathogenic Escherichia coli (EPEC) is a bacterium that causes attaching/effacing (A/E) lesions and serious diarrheal disease, a major health issue in developing countries. EPEC pathogenicity results from the effect of virulence factor...
Dietary modulation of gut microbiota affects susceptibility to drug-induced liver injury [0.03%]
饮食调节肠道菌群影响药物性肝损伤的易感性
Han Pan,Delei Song,Zhiyi Wang et al.
Han Pan et al.
The rising incidence of drug-induced liver injury (DILI) parallels contemporary dietary shifts that have transformed the composition of human gut microbiota. The relationship between these phenomena remains unknown. Here, it is unveiled tha...
Unexpected vulnerability of Enterococcus faecium to polymyxin B under anaerobic condition [0.03%]
枯草色芽孢杆菌在厌氧条件下意外易受多粘菌素B的影响
Yongjun Son,Bitnara Kim,Pureun Kim et al.
Yongjun Son et al.
Gram-positive Enterococcus faecium exhibited higher susceptibility (>4-fold) to polymyxin B (PMB), the canonical antimicrobial peptide against Gram-negative bacteria, under anaerobic condition than aerobic condition. Anaerobically grown E. ...
Role of gut microbes in acute lung injury/acute respiratory distress syndrome [0.03%]
肠道菌群在急性肺损伤和急性呼吸窘迫综合征中的作用
Zixuan Ren,Zhihuan Zheng,Xiujing Feng
Zixuan Ren
Acute lung injury (ALI) is an acute, diffuse inflammatory lung condition triggered by factors of severe infections, trauma, shock, burns, ischemia-reperfusion, and mechanical ventilation. It is primarily characterized by refractory hypoxemi...
Dietary inulin ameliorates obesity-induced severe acute pancreatitis via gut-pancreas axis [0.03%]
饮食中的低聚果糖通过肠-胰腺轴改善肥胖引起的重症急性胰腺炎
Xin Li,Pan Zheng,Yaoyu Zou et al.
Xin Li et al.
Obesity is a definitive factor of severity and mortality of acute pancreatitis (AP), and gut microbiota dysbiosis is involved in its pathogenesis. However, the effect of gut microbiota modulation by dietary components on high fat diet (HFD)...