Multifunctional dietary approach reduces intestinal inflammation in relation with changes in gut microbiota composition in subjects at cardiometabolic risk: the SINFONI project [0.03%]
一种多效膳食方法可降低心血管代谢危险人群的肠道炎症，并通过改变肠道菌群构成相关联：SINFONI项目
Hugo Hornero-Ramirez,Arianne Morisette,Bruno Marcotte et al.
Hugo Hornero-Ramirez et al.
The development of cardiometabolic (CM) diseases is associated with chronic low-grade inflammation, partly linked to alterations of the gut microbiota (GM) and reduced intestinal integrity. The SINFONI project investigates a multifunctional...
Randomized Controlled Trial
Gut microbes. 2025 Dec;17(1):2438823. DOI:10.1080/19490976.2024.2438823 2025
Faecal metaproteomics analysis reveals a high cardiovascular risk profile across healthy individuals and heart failure patients [0.03%]
粪便宏蛋白质组分析揭示了健康人和心力衰竭患者中的高心血管风险特征
Chaoran Yang,Leticia Camargo Tavares,Han-Chung Lee et al.
Chaoran Yang et al.
The gut microbiota is a crucial link between diet and cardiovascular disease (CVD). Using fecal metaproteomics, a method that concurrently captures human gut and microbiome proteins, we determined the crosstalk between gut microbiome, diet,...
Systematically-designed mixtures outperform single fibers for gut microbiota support [0.03%]
系统设计的混合物在改善肠道微生物群方面优于单一纤维
T M Cantu-Jungles,V Agamennone,T J Van den Broek et al.
T M Cantu-Jungles et al.
Dietary fiber interventions to modulate the gut microbiota have largely relied on isolated fibers or specific fiber sources. We hypothesized that fibers systematically blended could promote more health-related bacterial groups. Initially, p...
T cells regulate intestinal motility and shape enteric neuronal responses to intestinal microbiota [0.03%]
T细胞调控肠蠕动以及肠道菌群对肠神经反应的影响
Patricia Rodrigues Marques de Souza,Catherine M Keenan,Laurie E Wallace et al.
Patricia Rodrigues Marques de Souza et al.
How the gut microbiota and immune system maintain intestinal homeostasis in concert with the enteric nervous system (ENS) remains incompletely understood. To address this gap, we assessed small intestinal transit, enteric neuronal density, ...
Non-stochastic reassembly of a metabolically cohesive gut consortium shaped by N-acetyl-lactosamine-enriched fibers [0.03%]
以N-乙酰乳糖胺富集纤维形塑代谢共栖性的肠道菌群 Consortium 译为“菌群”、“菌丛”或“菌群集合”均可。
Madison Moore,Hunter D Whittington,Rebecca Knickmeyer et al.
Madison Moore et al.
Diet is one of the main factors shaping the human microbiome, yet our understanding of how specific dietary components influence microbial consortia assembly and subsequent stability in response to press disturbances - such as increasing re...
The regulatory effect of chitooligosaccharides on islet inflammation in T2D individuals after islet cell transplantation: the mechanism behind Candida albicans abundance and macrophage polarization [0.03%]
壳寡糖对T2D受者胰岛移植后胰岛炎的调控作用：其机制与白色念珠菌增多及巨噬细胞极化有关
Yayu Zhang,Xiaoguo Ji,Kunlin Chang et al.
Yayu Zhang et al.
Islet cell transplantation (ICT) represents a promising therapeutic approach for addressing diabetes mellitus. However, the islet inflammation during transplantation significantly reduces the surgical outcome rate, which is related to the p...
Xuan-Qi Zheng,Ding-Ben Wang,Yi-Rong Jiang et al.
Xuan-Qi Zheng et al.
Osteoporosis is an age-related bone metabolic disease. As an essential endocrine organ, the skeletal system is intricately connected with extraosseous organs. The crosstalk between bones and other organs supports this view. In recent years,...
Genomic island-encoded LmiA regulates acid resistance and biofilm formation in enterohemorrhagic Escherichia coli O157:H7 [0.03%]
基因岛编码的LmiA调节出血性大肠杆菌O157:H7的酸耐受性和生物被膜形成能力
Hongmin Sun,Lingyan Jiang,Jingnan Chen et al.
Hongmin Sun et al.
Enterohemorrhagic Escherichia coli (EHEC) O157:H7 is an important intestinal pathogen that causes severe foodborne diseases. We previously demonstrated that the genomic island-encoded regulator LmiA activates the locus of enterocyte effacem...
Comparative analysis of the duodenojejunal microbiome with the oral and fecal microbiomes reveals its stronger association with obesity and nutrition [0.03%]
与口腔和粪便微生物组的比较分析揭示了十二指肠-空肠微生物组与肥胖及营养的关系更密切
Emilie Steinbach,Eugeni Belda,Rohia Alili et al.
Emilie Steinbach et al.
The intestinal microbiota is increasingly recognized as a crucial player in the development and maintenance of various chronic conditions, including obesity and associated metabolic diseases. While most research focuses on the fecal microbi...
Comparative Study
Gut microbes. 2024 Jan-Dec;16(1):2405547. DOI:10.1080/19490976.2024.2405547 2024
A universe of human gut-derived bacterial prophages: unveiling the hidden viral players in intestinal microecology [0.03%]
一个人类肠道来源的噬菌体宇宙：揭示肠微生态中的隐藏病毒参与者
Zhangming Pei,Yufei Liu,Yutao Chen et al.
Zhangming Pei et al.
Prophages, which are an existing form of temperate phages that integrate into host genomes, have been found extensively present in diverse bacterial species. The human gut microbiome, characterized by its complexity, dynamism, and interconn...