Comparing Campylobacter jejuni to three other enteric pathogens in OligoMM12 mice reveals pathogen-specific host and microbiota responses [0.03%]
与三种其他肠道致病菌比较的小鼠OligoMM12模型中宿主和微生物群的特定反应揭示了幽门螺杆菌的特征
Mathias K-M Herzog,Audrey Peters,Nizar Shayya et al.
Mathias K-M Herzog et al.
Campylobacter jejuni, non-typhoidal Salmonella spp., Listeria monocytogenes and enteropathogenic/enterohemorrhagic Escherichia coli (EPEC/EHEC) are leading causes of food-borne illness worldwide. Citrobacter rodentium has been used to model...
Comparative Study
Gut microbes. 2025 Dec;17(1):2447832. DOI:10.1080/19490976.2024.2447832 2025
Dysbiosis of infant gut microbiota is related to the altered fatty acid composition of human milk from mothers with gestational diabetes mellitus: a prospective cohort study [0.03%]
母体妊娠期糖尿病影响婴儿肠道菌群与脂肪酸组成:一项前瞻性队列研究
Kelei Li,Jin Jin,Zhizuo Liu et al.
Kelei Li et al.
Gestational diabetes mellitus (GDM) is known to be associated with dysbiosis of offspring gut microbiota, but the mechanism remains unclear. The present prospective study explored the role of human milk fatty acid composition in this associ...
Reinvestigation into the role of lipopolysaccharide Glycosyltransferases in Helicobacter pylori protein glycosylation [0.03%]
幽门螺旋杆菌蛋白质糖基化中脂多糖糖基转移酶的作用机制再研究
Hong Li,Xiaoqiong Tang,Tiandi Yang et al.
Hong Li et al.
Protein glycosylation has been considered as a fundamental phenomenon shared by all domains of life. In Helicobacter pylori, glycosylation of flagellins A and B with pseudaminic acid have been rigorously confirmed and shown to be essential ...
From chaos to order: optimizing fecal microbiota transplantation for enhanced immune checkpoint inhibitors efficacy [0.03%]
从混乱到秩序:优化粪便微生物移植以增强免疫检查点抑制剂的疗效
Anqi Lin,Aimin Jiang,Lihaoyun Huang et al.
Anqi Lin et al.
The integration of fecal microbiota transplantation (FMT) with immune checkpoint inhibitors (ICIs) presents a promising approach for enhancing cancer treatment efficacy and overcoming therapeutic resistance. This review critically examines ...
Epidemiology of bacterial biofilms on polyps and normal tissues in a screening colonoscopy cohort [0.03%]
筛查结肠镜队列中息肉和正常组织细菌生物膜的流行病学特征
Julia L Drewes,Samara B Rifkin,Madison McMann et al.
Julia L Drewes et al.
Background: Invasive bacterial biofilms are implicated in colorectal cancer. However, their prevalence on histologically normal tissues and polyps is not well established, and risk factors of biofilms have not been previo...
Observational Study
Gut microbes. 2025 Dec;17(1):2452233. DOI:10.1080/19490976.2025.2452233 2025
Digging deeper into necrotizing enterocolitis: bridging clinical, microbial, and molecular perspectives [0.03%]
探究坏死性小肠结肠炎的深层原因:临床、微生物和分子视角的结合
Deshuang Zhang,Dongke Xie,Yi Qu et al.
Deshuang Zhang et al.
Necrotizing Enterocolitis (NEC) is a severe, life-threatening inflammatory condition of the gastrointestinal tract, especially affecting preterm infants. This review consolidates evidence from various biomedical disciplines to elucidate the...
Limosilactobacillus reuteri - a probiotic gut commensal with contextual impact on immunity [0.03%]
刘氏生态乳杆菌——一种具有免疫情境影响的益生菌肠道共生菌
Amanda H Lee,Daphne Michelle Rodriguez Jimenez,Marlies Meisel
Amanda H Lee
The gut microbiome plays a key role in human health, influencing various biological processes and disease outcomes. The historical roots of probiotics are traced back to Nobel Laureate Élie Metchnikoff, who linked the longevity of Bulgaria...
Inactivation of glutathione S-transferase alpha 4 blocks Enterococcus faecalis-induced bystander effect by promoting macrophage ferroptosis [0.03%]
谷胱甘肽S转移酶α4失活通过促进巨噬细胞铁死亡来抑制粪肠球菌诱导的旁观者效应
Yuanyuan Ju,Chunhua Ma,Lin Huang et al.
Yuanyuan Ju et al.
Enterococcus faecalis-infected macrophages produce 4-hydroxynonenal (4-HNE) that mediates microbiota-induced bystander effect (MIBE) leading to colorectal cancer (CRC). Glutathione S-transferase alpha 4 (Gsta4), a specific detoxifying enzym...
Staphylococcus warneri dampens SUMOylation and promotes intestinal inflammation [0.03%]
金黄色葡萄球菌减缓SUMO化并促进肠道炎症
Léa Loison,Marion Huré,Benjamin Lefranc et al.
Léa Loison et al.
Gut bacteria play key roles in intestinal physiology, via the secretion of diversified bacterial effectors. Many of these effectors remodel the host proteome, either by altering transcription or by regulating protein post-translational modi...
Synergistic and off-target effects of bacteriocins in a simplified human intestinal microbiome: implications for Clostridioides difficile infection control [0.03%]
bacteriocin对简化的人类肠道微生物组的协同和脱靶效应:对控制艰难梭菌感染的意义
Natalia S Ríos Colombo,R Paul Ross,Colin Hill
Natalia S Ríos Colombo
Clostridioides difficile is a major cause of nosocomial diarrhea. As current antibiotic treatment failures and recurrence of infections are highly frequent, alternative strategies are needed for the treatment of this disease. This study exp...