Roseburia hominis improves host metabolism in diet-induced obesity [0.03%]
Roseburia hominis改善饮食诱导肥胖的宿主代谢
Wenli Huang,Wenyi Zhu,Yu Lin et al.
Wenli Huang et al.
Next-generation live biotherapeutics are promising to aid the treatment of obesity and metabolic diseases. Here, we reported a novel anti-obesity probiotic candidate, Roseburia hominis, that was depleted in stool samples of obese subjects c...
Gut microbiome shifts in adolescents after sleeve gastrectomy with increased oral-associated taxa and pro-inflammatory potential [0.03%]
袖状胃切除术后青少年肠道微生物的变化，伴随口腔相关细菌的增加和促炎潜力的增强
Cynthia O Akagbosu,Kathryn E McCauley,Sivaranjani Namasivayam et al.
Cynthia O Akagbosu et al.
Bariatric surgery is highly effective in achieving weight loss in children and adolescents with severe obesity, however the underlying mechanisms are incompletely understood, and gut microbiome changes are unknown. Here, we show that adoles...
Profiling the gut microbiota to assess infection risk in Klebsiella pneumoniae-colonized patients [0.03%]
通过分析肠道微生物菌群来评估 Klebsiella pneumoniae 定植患者的感染风险
Flavio De Maio,Delia Mercedes Bianco,Giulia Santarelli et al.
Flavio De Maio et al.
Vornhagen et al. introduced a model combining gut microbiota structure and Klebsiella pneumoniae genotype to assess infection risk in K. pneumoniae-colonized patients. Building on their findings, we investigated the gut microbiota compositi...
Gut microbiome changes with micronutrient supplementation in children with attention-deficit/hyperactivity disorder: the MADDY study [0.03%]
注意力缺陷/多动障碍儿童微量营养素补充与肠道微生物群的变化：MADDY研究
Hayleigh K Ast,Matthew Hammer,Shiqi Zhang et al.
Hayleigh K Ast et al.
Micronutrients have demonstrated promise in managing inattention and emotional dysregulation in children with attention-deficit/hyperactivity disorder (ADHD). One plausible pathway by which micronutrients improve symptoms is the gut microbi...
Randomized Controlled Trial
Gut microbes. 2025 Dec;17(1):2463570. DOI:10.1080/19490976.2025.2463570 2025
Interplay of m6A RNA methylation and gut microbiota in modulating gut injury [0.03%]
m6A RNA甲基化和肠道微生物在调节肠损伤中的相互作用
Haixia Wang,Juanjuan Han,Xin-An Zhang
Haixia Wang
The gut microbiota undergoes continuous variations among individuals and across their lifespan, shaped by diverse factors encompassing diet, age, lifestyle choices, medication intake, and disease states. These microbial inhabitants play a p...
Microbiota-derived IPA alleviates intestinal mucosal inflammation through upregulating Th1/Th17 cell apoptosis in inflammatory bowel disease [0.03%]
微生物群衍生的IPA通过上调炎症性肠病中Th1 / Th17细胞的凋亡来减轻肠道粘膜炎症
Han Gao,Mingming Sun,Ai Li et al.
Han Gao et al.
The gut microbiota-derived metabolite indole-3-propionic acid (IPA) plays an important role in maintaining intestinal mucosal homeostasis, while the molecular mechanisms underlying IPA regulation on mucosal CD4+ T cell functions in inflamma...
Salmonella utilizes L-arabinose to silence virulence gene expression for accelerated pathogen growth within the host [0.03%]
沙门氏菌利用L-阿拉伯糖使毒力基因表达沉默以加速病原体在宿主体内的生长
Jingchen Yu,Huang Tang,Yana Chen et al.
Jingchen Yu et al.
Carbon source is an important nutrient for bacteria to sustain growth and often acts as a signal that modulates virulence expression. L-arabinose is produced by plants and plays an important role in regulating the global gene expression of ...
Time-restricted feeding promotes glucagon-like peptide-1 secretion and regulates appetite via tryptophan metabolism of gut Lactobacillus in pigs [0.03%]
限时进食通过肠道乳酸菌的色氨酸代谢促进猪的胰高血糖素样肽-1分泌并调节食欲
Qiuke Li,Ding Tan,Shijie Xiong et al.
Qiuke Li et al.
Previous clinical trials have shown that time-restricted feeding can be involved in regulating the metabolic health of humans and animals. However, the underlying mechanism has not been fully explored. In this study, the pig model was emplo...
Probiotic supplementation mitigates sex-dependent nociceptive changes and gut dysbiosis induced by prenatal opioid exposure [0.03%]
产前阿片类药物暴露引起的性别依赖性疼痛变化和肠道菌群失调可被益生元补充剂缓解
Salma Singh,Yaa Abu,Danielle Antoine et al.
Salma Singh et al.
The gut microbiome has emerged as a promising target for modulating adverse effects of opioid exposure due to its significant role in health and disease. Opioid use disorder (OUD) has become increasingly prevalent, specifically in women of ...
IgG-seq identifies immune-reactive enteric bacteria in Crohn's disease with spondyloarthritis [0.03%]
IgG-seq识别具有脊柱关节炎的克罗恩病中的免疫反应性肠道细菌
Grace A Maldarelli,Maeva Metz,Seun Oguntunmibi et al.
Grace A Maldarelli et al.
Joint inflammation is the most common extraintestinal manifestation of Crohn's disease (CD). Although alterations in the enteric microbiota are described in CD with spondyloarthritis (CD-SpA), it is not known whether distinct taxa serve as ...