Life-course socioeconomic position and the gut microbiome in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) [0.03%]
生命历程中的社会经济地位和西班牙裔社区健康研究/拉丁美洲人研究(HCHS / SOL)中的肠道微生物群
Monica A Batalha,Madison N LeCroy,Juan Lin et al.
Monica A Batalha et al.
Socioeconomic position (SEP) in childhood and beyond may influence the gut microbiome, with implications for disease risk. Studies evaluating the relationship between life-course SEP and the gut microbiome are sparse, particularly among His...
Dysregulation of gut microbiota stimulates NETs-driven HCC intrahepatic metastasis: therapeutic implications of healthy faecal microbiota transplantation [0.03%]
肠道微生物群失调刺激NETs驱动的HCC肝内转移：健康粪便菌群移植的治疗意义
Zhe Deng,Si Mei,Zhaoguang Ouyang et al.
Zhe Deng et al.
The stringent regulation of intrahepatic metastases is essential for improving survival outcomes in patients with hepatocellular carcinoma (HCC). This study investigated the impact of gut microbiota on intrahepatic metastasis of HCC and eva...
Human colitis-associated colorectal carcinoma progression is accompanied by dysbiosis with enriched pathobionts [0.03%]
人类结肠炎相关的结直肠癌进展伴有菌群失调和条件致病菌的富集
Amr H Masaadeh,Mohamed Eletrebi,Bishal Parajuli et al.
Amr H Masaadeh et al.
Dysbiosis and pathobionts contribute to inflammation and the risk of colitis-associated carcinoma (CAC) in animal models, but their roles in humans with this uncommon disease are unknown. We identified microbiome differences in human CAC co...
Microbial micronutrient sharing, gut redox balance and keystone taxa as a basis for a new perspective to solutions targeting health from the gut [0.03%]
微生物微量元素共享，肠道氧化还原平衡和关键分类群作为解决肠道健康问题的新视角基础
Robert E Steinert,Ateequr Rehman,Mehdi Sadaghian Sadabad et al.
Robert E Steinert et al.
In health, the gut microbiome functions as a stable ecosystem maintaining overall balance and ensuring its own survival against environmental stressors through complex microbial interaction. This balance and protection from stressors is mai...
Novel insights into carbohydrate utilisation, antimicrobial resistance, and sporulation potential in Roseburia intestinalis isolates across diverse geographical locations [0.03%]
不同地理来源的肠道玫瑰菌碳水化合物利用，抗微生物阻力和产孢潜力的新见解
Indrani Mukhopadhya,Jennifer C Martin,Sophie Shaw et al.
Indrani Mukhopadhya et al.
Roseburia intestinalis is one of the most abundant and important butyrate-producing human gut anaerobic bacteria that plays an important role in maintaining health and is a potential next-generation probiotic. We investigated the pangenome ...
The immune response modulated by inoculation of commensal bacteria at birth impacts the gut microbiota and prevents Salmonella colonization [0.03%]
出生时接种共生菌所调节的免疫反应影响肠道微生物群并预防沙门氏菌定植
Florent Kempf,Rosanna Drumo,Anne Marie Chaussé et al.
Florent Kempf et al.
Super- and low-shedding phenomena have been observed in genetically homogeneous hosts infected by a single bacterial strain. To decipher the mechanisms underlying these phenotypes, we conducted an experiment with chicks infected with Salmon...
Gut microbiome-driven regulation of sex hormone homeostasis: a potential neuroendocrine connection [0.03%]
肠道微生物群驱动的性激素稳态调控：潜在的神经内分泌联系
Anna Clapp Organski,Bartek Rajwa,Anjali Reddivari et al.
Anna Clapp Organski et al.
The gut microbiome is known to have a bidirectional relationship with sex hormone homeostasis; however, its role in mediating interactions between the primary regulatory axes of sex hormones and their productions is yet to be fully understo...
Microbiota and metabolite-based prediction tool for colonic polyposis with and without a known genetic driver [0.03%]
基于微生物群和代谢物的结肠息肉预测工具，包括已知的基因驱动器和未知基因驱动器的情况
Bryson W Katona,Ashutosh Shukla,Weiming Hu et al.
Bryson W Katona et al.
Despite extensive investigations into the microbiome and metabolome changes associated with colon polyps and colorectal cancer (CRC), the microbiome and metabolome profiles of individuals with colonic polyposis, including those with (Gene-p...
Resistance to quorum sensing inhibition spreads more slowly during host infection than antibiotic resistance [0.03%]
对抗群体感应抑制的抗性在宿主感染过程中的传播速度比抗生素抗性慢
Tom Defoirdt
Tom Defoirdt
Antibiotic resistance is a rising problem and new and sustainable strategies to combat bacterial (intestinal) infections are therefore urgently needed. One promising strategy under intense investigation is the inhibition of quorum sensing, ...
Integrating multi-omics data to reveal the host-microbiota interactome in inflammatory bowel disease [0.03%]
整合多组学数据揭示炎症性肠病的宿主-微生物相互作用组
Fengyuan Su,Meng Su,Wenting Wei et al.
Fengyuan Su et al.
Numerous studies have accelerated the knowledge expansion on the role of gut microbiota in inflammatory bowel disease (IBD). However, the precise mechanisms behind host-microbe cross-talk remain largely undefined, due to the complexity of t...