Multi-omics: Opportunities for research on mechanism of type 2 diabetes mellitus [0.03%]
多组学研究在2型糖尿病机制研究中的应用机遇与挑战
Shuai Wang,Hui Yong,Xiao-Dong He
Shuai Wang
Type 2 diabetes mellitus (T2DM) is a burdensome global disease. In-depth understanding of its mechanism will help to optimize diagnosis and treatment, which reduces the burden. Multi-omics research has unparalleled advantages in contributin...
Comprehensive overview of human serum albumin glycation in diabetes mellitus [0.03%]
糖尿病 mellitus 中的人血清白蛋白糖基化的全面概述
Hong-Yan Qiu,Ning-Ning Hou,Jun-Feng Shi et al.
Hong-Yan Qiu et al.
The presence of excess glucose in blood is regarded as a sweet hurt for patients with diabetes. Human serum albumin (HSA) is the most abundant protein in human plasma, which undergoes severe non-enzymatic glycation with glucose in patients ...
Diego F Cuadros,Jingjing Li,Godfrey Musuka et al.
Diego F Cuadros et al.
Diabetes mellitus (DM) is a growing epidemic with global proportions. It is estimated that in 2019, 463 million adults aged 20-79 years were living with DM. The latest evidence shows that DM continues to be a significant global health chall...
Immunometabolic bases of type 2 diabetes in the severity of COVID-19 [0.03%]
2型糖尿病患者的COVID-19重症化免疫代谢机制
Rebeca Viurcos-Sanabria,Galileo Escobedo
Rebeca Viurcos-Sanabria
The outbreak of coronavirus disease 2019 (COVID-19) is caused by the novel severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). COVID-19 and type 2 diabetes (T2D) have now merged into an ongoing global syndemic that is threatening ...
Carly Yim,Kerry Mansell,Nassrein Hussein et al.
Carly Yim et al.
This review focuses on the development of hyperglycemia arising from widely used cancer therapies spanning four drug classes. These groups of medications were selected due to their significant association with new onset hyperglycemia, or of...
Giacomina Brunetti,Gabriele D&#x;Amato,Stefania De Santis et al.
Giacomina Brunetti et al.
Bone loss associated with type 1 diabetes mellitus (T1DM) begins at the onset of the disease, already in childhood, determining a lower bone mass peak and hence a greater risk of osteoporosis and fractures later in life. The mechanisms unde...
Diabetic patients with chronic kidney disease: Non-invasive assessment of cardiovascular risk [0.03%]
糖尿病肾病患者的血管病变筛查及心血管风险评估非侵入性手段
Nejc Piko,Sebastjan Bevc,Robert Ekart et al.
Nejc Piko et al.
The prevalence and burden of diabetes mellitus and chronic kidney disease on global health and socioeconomic development is already heavy and still rising. Diabetes mellitus by itself is linked to adverse cardiovascular events, and the pres...
Taymour Mostafa,Ibrahim A Abdel-Hamid
Taymour Mostafa
Diabetes mellitus (DM) is a metabolic disorder that is characterized by elevated blood glucose levels due to absolute or relative insulin deficiency, in the background of β-cell dysfunction, insulin resistance, or both. Such chronic hyperg...
Bing-Yan Li,Wei Tan,Jing-Ling Zou et al.
Bing-Yan Li et al.
Diabetic retinopathy (DR) is one of the major causes of visual impairment and irreversible blindness in developed regions. Aside from abnormal angiogenesis, inflammation is the most specific and might be the initiating factor of DR. As a ke...
Exploring new treatment options for polycystic ovary syndrome: Review of a novel antidiabetic agent SGLT2 inhibitor [0.03%]
探索多囊卵巢综合征新的治疗手段——一种新型降糖药物SGLT2抑制剂的述评
Jelena Marinkovic-Radosevic,Maja Cigrovski Berkovic,Egon Kruezi et al.
Jelena Marinkovic-Radosevic et al.
Polycystic ovary syndrome (PCOS) is the most common endocrinopathy in women of reproductive age associated with long-term metabolic and cardiovascular consequences. A plethora of symptoms and their severity differentiate on an individual le...