Mesenchymal stem cell-derived extracellular vesicles: A promising therapeutic strategy in diabetic osteoporosis [0.03%]
间充质干细胞源性外泌体在糖尿病骨质疏松症治疗中的应用前景
Ya-Jing Yang,Xi-Er Chen,Xu-Chang Zhou et al.
Ya-Jing Yang et al.
Diabetic osteoporosis (DOP) is a serious complication of diabetes mellitus. It is urgent to explore efficient clinical treatment strategies for DOP. It has been found that mesenchymal stem cell-derived extracellular vesicles (MSC-EVs), as a...
Sarcopenia-associated factors and their bone mineral density levels in middle-aged and elderly male type 2 diabetes patients [0.03%]
与中老年男性2型糖尿病患者骨骼肌减少相关的因素及其骨矿密度水平分析
De-Qing Chen,Yong-Xin Wu,Ying-Xiao Zhang et al.
De-Qing Chen et al.
Background: Chronic hyperglycemia can damage the microcirculation, which impairs the function of various organs and tissues and predisposes individuals to chronic complications. Sarcopenia (SP) is the age-related decline ...
Peroxisome proliferator-activated receptor gamma mutation in familial partial lipodystrophy type three: A case report and review of literature [0.03%]
家族性部分脂odystrophy型三例突变报告及文献复习
Chao-Jun Wu,Hao Liu,Li-Juan Tu et al.
Chao-Jun Wu et al.
Background: Familial partial lipodystrophy disease (FPLD) is a collection of rare genetic diseases featuring partial loss of adipose tissue. However, metabolic difficulties, such as severe insulin resistance, diabetes, hy...
Application value of high-pressure-resistant peripherally inserted central catheters in enhanced computer tomography of diabetic patients with malignant tumors [0.03%]
高压力耐受外周插入中心静脉导管在糖尿病合并恶性肿瘤患者强化计算机断层扫描中的应用价值
Li Zhang,Hui-Feng Yan
Li Zhang
Background: Individuals with diabetes mellitus have a higher risk of developing malignant tumors, and diagnosing these tumors can be challenging. Aim: ...
What is the optimal dialysis method for diabetic patients with end stage kidney disease? [0.03%]
糖尿病肾病终末期患者的最优血液净化方式是什么？
Nirmal Noor Kheber,Abdulqadir J Nashwan
Nirmal Noor Kheber
Diabetes is one of the most catastrophic diseases ruling every corner of the world, and this has led to elevated incidents of end-stage kidney disease (ESKD). The standard treatment for ESKD is kidney transplantation/replacement, which is l...
Intersection of the glymphatic system and diabetes: Navigating a new frontier [0.03%]
甘淋巴系统与糖尿病的交集：探索新的前沿领域
Asad Gul Rao,Abdulqadir J Nashwan
Asad Gul Rao
Diabetes is one of the most devastating medical dilemmas impacting every region of the world severely. The study by Tian et al investigates glymphatic system dysfunction in the context of glucose metabolism and diabetes, using diffusion ten...
Role of intestinal glucagon-like peptide-1 in impaired counter-regulatory responses to hypoglycemia [0.03%]
肠胰高糖素样肽-1在低血糖反应异常中的作用
Manjunath Havalappa Dodamani,Juniali Hatwal,Akash Batta
Manjunath Havalappa Dodamani
Patients with type 1 diabetes mellitus (T1DM) experience multiple episodes of hypoglycemia, resulting in dysfunctional counter-regulatory responses with time. The recent experimental study by Jin et al explored the role of intestinal glucag...
Intestinal glucagon-like peptide-1 in hypoglycemic counterregulation for type 1 diabetes management [0.03%]
肠胰高血糖素样肽-1在1型糖尿病低血糖反调节中的作用
Ke-Xin Zhang,Cheng-Xia Kan,Yu-Qun Wang et al.
Ke-Xin Zhang et al.
Type 1 diabetes (T1D) is characterized by the autoimmune destruction of pancreatic beta cells, leading to absolute insulin deficiency and the need for exogenous insulin. A significant concern in T1D management is hypoglycemia, which is wors...
Shikonin protects mitochondria through the NFAT5/AMPK pathway for the treatment of diabetic wounds [0.03%]
漆enoside通过NFAT5/AMPK途径保护线粒体治疗糖尿病伤口
Lu-Sha Cen,Yi Cao,Yi-Mai Zhou et al.
Lu-Sha Cen et al.
Background: Shikonin is a natural remedy that is effective at treating diabetic wounds. NFAT5 is a potential therapeutic target for diabetes, and mitochondrial function is essential for wound healing. However, the relatio...
Teneligliptin mitigates diabetic cardiomyopathy through inflammasome inhibition: Insights from experimental studies [0.03%]
通过抑制炎症小体缓解糖尿病心肌病：来自实验研究的新观点テンeligliptin在糖尿病心肌病中的作用机制研究
Chun-Yao Cheng,Wen-Rui Hao,Ju-Chi Liu et al.
Chun-Yao Cheng et al.
This article provides commentary on the article by Zhang et al. In this original research, Zhang et al investigated the therapeutic potential of teneligliptin for diabetic cardiomyopathy (DCM), which was mediated by targeting the NOD-like r...