Reasons for discontinuing tirzepatide in randomized controlled trials: A systematic review and meta-analysis [0.03%]
tirzepatide随机对照试验停药原因的系统评价和.meta.分析
Abul Bashar Mohammad Kamrul-Hasan,Joseph M Pappachan,Deep Dutta et al.
Abul Bashar Mohammad Kamrul-Hasan et al.
Background: Despite therapeutic benefits, discontinuation of tirzepatide is common in randomized controlled trials (RCTs) due to adverse events (AEs) and other causes. No previous systematic reviews have explored the reas...
Characteristic dysbiosis in patients with type 2 diabetes and hyperuricemia, and the effect of empagliflozin on gut microbiota [0.03%]
2型糖尿病合并高尿酸血症患者的特征性肠菌失调及恩格列净对肠道菌群的影响
Xin-Ru Deng,Yu-Jia Zhai,Xiao-Yang Shi et al.
Xin-Ru Deng et al.
Background: Gut microbiota play a crucial role in metabolic diseases, including type 2 diabetes (T2DM) and hyperuricemia (HUA). One-third of uric acid is excreted into the intestinal tract and further metabolized by gut m...
T helper 17 cells and interleukin-17 immunity in type 1 diabetes: From pathophysiology to targeted immunotherapies [0.03%]
辅助性T细胞17和白介素-17在1型糖尿病中的免疫反应:从病理生理到靶向免疫疗法
Georgi Vasilev,Maria Kokudeva,Elina Siliogka et al.
Georgi Vasilev et al.
Type 1 diabetes (T1D) is a chronic organ-specific autoimmune disorder characterized by a progressive loss of the insulin-secreting pancreatic beta cells, which ultimately results in insulinopenia, hyperglycemia and lifelong need for exogeno...
Dl-3-n-butylphthalide ameliorates diabetic foot ulcer by inhibiting apoptosis and promoting angiogenesis [0.03%]
Dl-3-丁基苯酞通过抑制凋亡和促进血管生成改善糖尿病足溃疡
Wu-Han Wei,Yuan-Ling Bai,Dong Zhu et al.
Wu-Han Wei et al.
Background: Diabetic foot ulcers (DFU) are estimated to affect about 18.6 million people worldwide annually. The pathogenesis of DFU is complex, and the available drugs are not effective. Dl-3-n-butylphthalide (NBP) is a ...
Clinical utility of glycated albumin and 1,5-anhydroglucitol in the screening and prediction of diabetes: A multi-center study [0.03%]
糖化血清白蛋白和1,5-脱水葡萄糖醇在糖尿病筛查及预测中的临床应用价值:一项多中心研究
Kam-Ching Ku,Junda Zhong,Erfei Song et al.
Kam-Ching Ku et al.
Background: Despite being the gold standard, the use of glycated hemoglobin (HbA1c) and fasting plasma glucose (FPG) for diagnosing dysglycemia is imperfect. In particular, a low level of agreement between HbA1c and FPG i...
Comprehensive impact of PPARG mutations in familial partial lipodystrophy type 3: Diagnosis, therapeutic strategies [0.03%]
PPARG突变在家族性部分脂代谢不良3型的综合影响:诊断与治疗策略
Heng-Li Lai,Liu Yang
Heng-Li Lai
This article reviews a paper in the World Journal of Diabetes. The study uncovers the link between PPARG gene mutations and metabolic disorders, such as insulin resistance, diabetes, and hypertriglyceridemia, and emphasizes the crucial role...
Cross-sectional study of the association between triglyceride glucose-body mass index and obstructive sleep apnea risk [0.03%]
甘油三酯葡萄糖-体质指数与阻塞性睡眠呼吸暂停风险的关联性横断面研究
Li Gong,Ming Su,Jing-Han Xu et al.
Li Gong et al.
Background: The triglyceride glucose-body mass index (TyG-BMI) is a novel indicator of insulin resistance (IR). Obstructive sleep apnea (OSA) is a prevalent disorder characterized by recurrent complete or partial collapse...
Gumpeny R Sridhar,Lakshmi Gumpeny
Gumpeny R Sridhar
ChatGPT, a popular large language model developed by OpenAI, has the potential to transform the management of diabetes mellitus. It is a conversational artificial intelligence model trained on extensive datasets, although not specifically h...
Glabridin and gymnemic acid alleviates choroid structural change and choriocapillaris impairment in diabetic rat's eyes [0.03%]
葛瑞忍和车前草酸缓解了糖尿病大鼠眼睛的脉络膜结构变化和脉络膜毛细血管损伤
Udomlak Matsathit,Manaras Komolkriengkrai,Wipapan Khimmaktong
Udomlak Matsathit
Background: Small blood vessels in the eyes are more susceptible to injury, which can lead to complications. However, since diabetic retinopathy is often a serious clinical condition, most of this study focuses on the vas...
Comprehensive review on diabetic foot ulcers and neuropathy: Treatment, prevention and management [0.03%]
糖尿病足溃疡和神经病变的综合回顾:治疗、预防和管理
Kehkashan Parveen,Malik Asif Hussain,Sadaf Anwar et al.
Kehkashan Parveen et al.
Diabetic foot (DF) is a major public health concern. As evident from numerous previous studies, supervision of DF ulcer (DFU) is crucial, and a specific quality check-up is needed. Patients should be educated about glycaemic management, DFU...