Histone lactylation: A key epigenetic modulator in the pathogenesis of metabolic dysfunction-associated steatohepatitis and alcoholic steatohepatitis [0.03%]
组蛋白乳酸化：代谢功能障碍相关steatohepatitis和酒精性脂肪肝病发病机制的关键表观遗传调控因子
Mable Misha Singh,Arunim Shah,Sangam Rajak et al.
Mable Misha Singh et al.
Metabolic dysfunction-associated steatohepatitis (MASH) and alcoholic steatohepatitis (ASH) are severe forms of chronic liver disease, characterized by inflammation, oxidative stress, lipid dysregulation, and fibrosis. Epigenetic changes, i...
Clinical study on the efficacy of laparoscopic hepatectomy via the retroperitoneal approach for treating liver tumors [0.03%]
后腹腔入路肝癌腹腔镜肝切除术的临床疗效研究
Zhen-Hao Fei,Xing-Fu Duan,Li-Hong Feng et al.
Zhen-Hao Fei et al.
Background: Laparoscopic hepatectomy has been widely accepted for the treatment of liver tumors. Compared with open surgery, it provides a reduced hospital stay, less intraoperative blood loss, less trauma, and fewer inci...
Performance of artificial intelligence in predicting hepatocellular carcinoma recurrence after thermal ablation: A systematic review [0.03%]
人工智能预测热消融后肝细胞癌复发的系统评价：%D%A性能如何？
Alessandro Posa,Marcello Lippi,Pierluigi Barbieri et al.
Alessandro Posa et al.
Background: Recurrence prediction of hepatocellular carcinoma (HCC) after thermal ablation represents a challenge that can impact patients' quality of life. Artificial intelligence (AI)-based radiomics models applied to v...
Refractory autoimmune hepatitis in children: Considerations for assessment and management [0.03%]
儿童难治性自身免疫性肝炎的评估和处理要点
Joseph Valamparampil,Rachel M Brown,Patrick McKiernan
Joseph Valamparampil
Refractory autoimmune hepatitis (AIH) is defined as intolerance of or unresponsiveness to standard immunosuppression and occurs in 10%-20% of children with AIH. Lack of response or slower than expected response to induction of remission wit...
Hepatic enhancement and signal intensity analysis on magnetic resonance imaging as prognostic biomarkers in advanced chronic liver disease [0.03%]
磁共振成像在晚期慢性肝病中的肝脏强化和信号强度分析作为预后生物标志物的价值评估
Bogdan-Ioan Stanciu,Marcela Iojiban,Andreea Morariu-Barb et al.
Bogdan-Ioan Stanciu et al.
Background: Advanced chronic liver disease is a progressive condition associated with high morbidity and mortality, leading to complications such as decompensation and hepatocellular carcinoma. Although prognostic scores ...
De novo arthropathy following glucocorticoid treatment for severe alcohol-associated hepatitis: Five case reports [0.03%]
糖皮质激素治疗重度酒精性肝炎后的新发关节病：5例报道
Queralt Herms,Sonia Torres,Patrick S Kamath et al.
Queralt Herms et al.
Background: Glucocorticoids (GC) are the cornerstone in the treatment of severe alcohol-associated hepatitis (SAH) but may be associated with adverse events. ...
He-He-Shu-Yang formula alleviates liver fibrosis by inhibiting hepatic stellate cell activation in vivo and in vitro [0.03%]
何木疏阳方通过体内、体外实验抑制肝星状细胞活化改善肝纤维化
Fo-Lai Zeng,Mei-Jie Shi,You-Sheng Mo et al.
Fo-Lai Zeng et al.
Background: Inhibition of liver fibrosis plays a crucial role in curbing the advancement of chronic disease to cirrhosis and even liver cancer. However, modern medicine currently lacks direct anti-fibrotic drugs. He-He-Sh...
Impact of age on autoimmune hepatitis: A comparative study of patients diagnosed before and after sixty [0.03%]
年龄对自身免疫性肝炎的影响：60岁前后诊断患者的比较研究
Javier Delgado,Marcelo Fuentes,Daniela Simian et al.
Javier Delgado et al.
Background: Autoimmune hepatitis (AIH) is characterized by inflammation, hepatocyte necrosis, autoantibodies, and elevated serum globulin levels. It can present at any age, with peaks reported at 30 years and after 60 yea...
Generic vs brand forms of direct acting antivirals for hepatitis C virus treatment in Egyptian children [0.03%]
埃及儿童丙型肝炎病毒治疗中的直接抗病毒药物的通用名与商标名形式的对比研究
Engy Mogahed,Haytham Ghita,Afaf Enayet et al.
Engy Mogahed et al.
Background: Direct acting antivirals have revolutionized hepatitis C virus (HCV) treatment. However, the high price of the brand forms is a barrier for their use in resource limited countries as Egypt. ...
Stereotactic body radiation therapy in patients with unresectable hepatocellular carcinoma and portal vein tumor thrombosis [0.03%]
不可切除的肝细胞癌合并门静脉瘤栓患者立体定向体部放射治疗回顾性分析
Divya Khosla,Venkata Krishna Vamsi Gade,Rakesh Kapoor et al.
Divya Khosla et al.
Background: About 35%-50% of patients with hepatocellular cancer (HCC) present with portal venous tumor thrombosis (PVTT). Stereotactic body radiation therapy (SBRT) offers a promising approach for locoregional treatment ...