Dynamic inflammation-based prognostication in acute-on-chronic liver failure: The COSSH-CAR model as a step forward in personalized risk stratification [0.03%]
急性重型肝炎动态炎症预后评估及COSSH-CAR模型在个体化风险分层中的应用价值
Noura A A Ebrahim,Thoraya A Farghaly,Soliman M A Soliman
Noura A A Ebrahim
Acute-on-chronic liver failure (ACLF) is a swiftly deteriorating condition characterized by profound systemic inflammation and failure of multiple organ systems, leading to high early mortality. There remains a critical need for more effect...
Norrapat Onpoaree,Nattinee Leelakanok,Anapat Sanpavat et al.
Norrapat Onpoaree et al.
Epstein-Barr virus (EBV) infection commonly occurs in children, particularly in developing countries. Most children infected with EBV are asymptomatic, though some develop significant complications, including EBV-associated malignancies, he...
Effects of tenofovir amibufenamide and entecavir on estimated glomerular filtration rate in treatment-naïve patients with chronic hepatitis B [0.03%]
恩替卡韦和泰诺福韦酯治疗初治慢性乙型肝炎患者对肾小球滤过率的影响
Shi-Peng Ma,Liang Wang,Yu-Liang Zhang et al.
Shi-Peng Ma et al.
Background: As a novel antiviral agent, the comparative renal safety of tenofovir amibufenamide (TMF) vs entecavir (ETV) in chronic hepatitis B (CHB) remains unclear. ...
Fatigue and circadian rhythm in non-cirrhotic primary biliary cholangitis: An exploratory comparison with primary sclerosing cholangitis and healthy controls [0.03%]
非肝硬化原发性胆汁性胆管炎的疲劳和昼夜节律：与原发性硬化性胆管炎和健康对照组的初步比较研究
Armando Curto,Michele Tanturli,Rocco Gabriele Iamello et al.
Armando Curto et al.
Background: Fatigue is common and debilitating in primary biliary cholangitis (PBC) without clear relation to disease stage; mechanisms remain unclear. Circadian disruption is reported in end-stage liver disease, but evid...
Advances in biliary stone management: Latest-generation extracorporeal shock wave lithotripsy vs laser lithotripsy for difficult bile duct stones [0.03%]
肝外胆道难取结石的治疗进展：新一代体外震波碎石术与激光碎石术之比较研究
Neeraj Singla,Katrevula Anudeep Venkata,Pradev Inavolu et al.
Neeraj Singla et al.
Background: Extracorporeal shock wave lithotripsy (ESWL) and laser lithotripsy (LL) are established alternatives for the management of difficult common bile duct (CBD) stones. However, there is limited evidence regarding ...
Should the routine use of the 6-minute walk test be implemented in liver disease assessment: Not so fast [0.03%]
不该在肝病评估中常规使用6分钟步行试验？且慢……
Marco E Diaz-Cordova,Ishani Sharma,William Pascal et al.
Marco E Diaz-Cordova et al.
End-stage liver disease (ESLD) is a debilitating condition that often leads to death. Once diagnosed with ESLD, a patient's quality of life decreases significantly. Well-established markers, such as the model for end-stage liver disease and...
Dynamic immune response and its influencing factors in COVID-19 patients with non-alcoholic fatty liver disease: A cohort study [0.03%]
非酒精性脂肪肝病COVID-19患者的动态免疫应答及其影响因素：群组研究
Pan Yan,Rui Li,Xiao-Yan Yuan et al.
Pan Yan et al.
Background: Dynamic alterations in lymphocyte subsets demonstrate significant correlations with clinical disease severity in patients with coronavirus disease 2019 (COVID-19). As the most prevalent chronic liver disease g...
Educational video modules for alcohol use disorder: A scalable tool to bridge the treatment gap in hepatology [0.03%]
针对肝病学的酒精使用障碍教育视频模块：一种弥合治疗差距的可扩展工具
Zi-Xiang Jin,Nian-Zhe Sun
Zi-Xiang Jin
The prospective cohort study by Twohig et al evaluates the efficacy of a novel educational video module (EVM) in promoting treatment engagement and reducing alcohol use among hospitalized patients with alcohol-associated liver disease (ALD)...
Qushi Huoxue ointment ameliorates metabolic associated steatotic liver disease through autophagy activation and ferroptosis inhibition [0.03%]
活血祛瘀膏通过激活自噬和抑制铁死亡改善与代谢相关脂肪性肝病
Yi-Yang Liu,Hong Qin,Hong-Xi Wu et al.
Yi-Yang Liu et al.
Background: Metabolic associated steatotic liver disease (MASLD) has become a growing global health burden, with its potential to progress to liver fibrosis, cirrhosis, and hepatocellular carcinoma. Qushi Huoxue ointment ...
Transjugular intrahepatic portosystemic shunt improves survival in anticoagulation-resistant hepatic sinusoidal obstructive syndrome patients: A multicenter retrospective study [0.03%]
经颈静脉肝内门体分流术可改善抗凝治疗抵抗性肝窦阻塞综合征患者的生存率：多中心回顾研究
Jing-Jing Tu,Han Zhang,De-Run Kong et al.
Jing-Jing Tu et al.
Background: Anticoagulation therapy is recommended during the acute or subacute stage for patients with pyrrolizidine alkaloid-hepatic sinusoidal obstruction syndrome (PA-HSOS). Transjugular intrahepatic portosystemic shu...