Integrated serum metabolomics reveal molecular mechanism of Xietu Hemu prescription on metabolic dysfunction-associated steatotic liver disease-related obesity [0.03%]
基于血清整合代谢组学的泄吐和血汤药对代谢性失常相关脂肪型肝病型肥胖的作用机制研究
Zhe Cheng,Yi-Fan Lu,Yi-Xian He et al.
Zhe Cheng et al.
Background: Xietu Hemu prescription (XHP), a Chinese patent formula, is optimized based on the theory of "phlegm-dampness" and has been clinically validated to effectively combat metabolic dysfunction-associated steatotic...
Jakub Janczura,Michał Brzdęk,Robert Flisiak et al.
Jakub Janczura et al.
Background: Steatotic liver disease (SLD) including metabolic dysfunction-associated SLD is the most prevalent chronic liver disease worldwide and is strongly associated with metabolic dysfunction as well as chronic hepat...
Sabrina Xin Zi Quek,Keith Wei Jie Ching,Kamarjit Mangat et al.
Sabrina Xin Zi Quek et al.
Background: Cerebrospinal fluid (CSF) pseudocysts are uncommon complications of ventriculoperitoneal (VP) shunts, usually occurring within 3 weeks to 10 years of insertion. We report a perihepatic CSF pseudocyst presentin...
Transcriptome profiles of peripheral blood mononuclear cells differentiate male adolescents with non-alcoholic fatty liver disease from healthy peers [0.03%]
外周血单个核细胞转录组谱型可区分出非酒精性脂肪肝病男性青少年和健康同龄人
Natalia Zeber-Lubecka,Jacek Michalkiewicz,Michalina Dabrowska et al.
Natalia Zeber-Lubecka et al.
Background: Numerous studies have reported specific expression profiles of peripheral blood mononuclear cells (PBMCs) that are associated with infectious, autoimmune, and inflammatory disorders, including chronic liver di...
Interplay between intestinal permeability and metabolic dysfunction-associated steatotic liver disease: Could there be a role for extra virgin olive oil consumption? [0.03%]
肠道通透性和与代谢功能障碍相关肝脂肪变性疾病之间的相互作用：是否有必要食用特级初榨橄榄油？
Lydia Giannitrapani,Marinella Ferraro,Aurelio Seidita et al.
Lydia Giannitrapani et al.
Metabolic dysfunction-associated steatotic liver disease is a multifaceted disease associated with obesity, insulin resistance (IR), type 2 diabetes mellitus - in a word, metabolic syndrome - which has been extensively studied because it is...
Drug-induced liver injury in inflammatory bowel disease: Challenges in diagnosis and monitoring [0.03%]
炎症性肠病的药物性肝损伤：诊断和监测的挑战
Arshdeep Singh,Arshia Bhardwaj,Harmeet Kaur et al.
Arshdeep Singh et al.
Drug-induced liver injury (DILI) is an important but often underrecognized complication in the management of inflammatory bowel disease (IBD), particularly in patients receiving long-term immunomodulatory or biologic therapies. Agents such ...
Albumin-bilirubin score as a practical tool for prognostication in metabolic-associated steatotic liver disease [0.03%]
白蛋白胆红素评分在代谢相关脂肪性肝病预后中的应用价值
Chung-Woo Lee
Chung-Woo Lee
Metabolic-associated steatotic liver disease (MASLD) has become the leading cause of chronic liver disease worldwide, yet reliable tools for prognostication remain limited. Fibrosis-based indices such as the fibrosis-4 and nonalcoholic fatt...
Ultrasound imaging in orthotopic hepatocellular carcinoma models: Promise, practicality, and points for refinement [0.03%]
异位肝细胞癌模型的超声成像：前景、实用性和改进要点
Devlina Ghosh,Alok Kumar
Devlina Ghosh
The study by Devan et al presents an ultrasound-based protocol for monitoring tumor growth in a syngeneic orthotopic rat model of hepatocellular carcinoma (HCC). This approach is commendable for its reproducibility, cost-effectiveness, and ...
Microplastics in metabolic dysfunction-associated steatotic liver disease: An emerging threat to liver health [0.03%]
微塑料在代谢功能紊乱相关性肝脂变性疾病中的作用：对肝脏健康的新威胁
Sangam Rajak,Ambuj Shahi,Abhishek Yadav et al.
Sangam Rajak et al.
Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly referred to as non-alcoholic fatty liver disease, is a major cause of end-stage liver disease worldwide. Numerous studies have demonstrated that the liver is predomi...
Severe hyperlipidemia associated with drug-induced cholestatic liver disease: A case report [0.03%]
与药物性胆汁淤积性肝病相关的重度高脂血症病例报告
Meng-Jiao Xu,Xin Wei,Yao Lu et al.
Meng-Jiao Xu et al.
Background: The global incidence of hyperlipidemia has been increasing on an annual basis, concomitant with improvements in living standards and dietary changes. Hyperlipidemia is closely associated with the development o...