Impact of alcohol-associated and metabolic dysfunction-associated steatotic liver diseases upon hepatic disorder and carcinogenesis in the current era [0.03%]
酒精相关和代谢功能异常相关的脂肪性肝病对当前时代肝脏疾病和癌症的影响
Tomohide Hori
Tomohide Hori
In this editorial, author specifically focuses upon metabolic dysfunction-associated steatotic liver disease (MASLD) and alcohol-associated liver diseases (ALD) in the current era. This editorial article is inspired by the observational stu...
Essential phospholipids and enzyme-based staging in nonalcoholic fatty liver disease: A call to action [0.03%]
非酒精性脂肪肝病的必需磷脂和基于酶的分期：行动呼吁
Ali Madian
Ali Madian
Nonalcoholic fatty liver disease, recently termed metabolic dysfunction-associated steatotic liver disease, affects 25% of adults globally, with a prevalence reaching 93% in obese individuals. The MANPOWER study, a post hoc analysis of 2843...
Metabolic associated steatotic liver disease in Qatar: Analysis of dietary patterns and nutrient intake [0.03%]
卡塔尔的代谢关联脂肪性肝病：饮食模式和营养素摄入分析
Joud Alalwani,Moutaz Derbala,Reema Tayyem et al.
Joud Alalwani et al.
Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a common and increasingly prevalent condition in the Middle East, but its determinants in the region are underexplored. Diet and lifestyle ar...
Explainable artificial intelligence and ensemble learning for hepatocellular carcinoma classification: State of the art, performance, and clinical implications [0.03%]
可解释的人工智能和集成学习在肝细胞癌分类中的应用：现状、性能及临床意义
Sami Akbulut,Cemil Colak
Sami Akbulut
Hepatocellular carcinoma (HCC) remains a leading cause of cancer-related mortality globally, necessitating advanced diagnostic tools to improve early detection and personalized targeted therapy. This review synthesizes evidence on explainab...
Mechanistic interplay between aflatoxin B1 and tissue inhibitor of metalloproteinase-3 in hepatocellular carcinoma [0.03%]
黄曲霉毒素B1与金属蛋白酶组织抑制剂-3在肝癌中的作用机制相互作用研究
Yan Luo,Li-Juan Wang,Cheng-Long Wang
Yan Luo
Hepatocellular carcinoma (HCC) is a major global health challenge, particularly in regions with high aflatoxin B1 (AFB1) exposure. This editorial explores the mechanistic interplay between AFB1 and tissue inhibitor of metalloproteinase-3 (T...
Clinical characteristics and genetic causes of unexplained pediatric liver disease [0.03%]
儿童原因不明肝病的临床特征和遗传病因
Yuan Chen,Zhi-Yi Wang,Bao-Qi Chen et al.
Yuan Chen et al.
Background: In recent years, the number of pediatric patients with unexplained liver disease has been increasing. Whole-exome sequencing (WES) technology has played a significant role in the diagnosis; however, related st...
Ginger mitigates acrylamide-induced hepatotoxicity through antioxidant and anti-inflammatory mechanisms in rats [0.03%]
生姜通过抗氧化和抗炎机制缓解丙烯酰胺致大鼠肝毒性
Ahmed El-Sayed Nour El Deen,Fatma Rashed,Amira Osman et al.
Ahmed El-Sayed Nour El Deen et al.
Background: Acrylamide (ACR), a toxic compound commonly found in heat-processed foods, poses a serious risk to liver health due to its oxidative and inflammatory effects. ...
Novel educational video module about alcohol use disorder increases treatment rates and decreases return to alcohol use [0.03%]
一种关于酒精使用障碍的新教育视频模块可提高治疗率并减少回退饮酒的现象
Patrick Twohig,Zachary P Slocum,Anna Willet et al.
Patrick Twohig et al.
Background: Patients and providers are often unaware of available treatment options for alcohol use disorder (AUD) and how to pursue them. Aim: ...
Current clinical research status and future treatment directions for liver cirrhosis combined with portal vein thrombosis [0.03%]
肝硬化合并门静脉血栓临床研究现状与未来治疗方向分析
Wen-Long He,Shuai Yan,Jia-Jie Lu et al.
Wen-Long He et al.
Portal vein thrombosis (PVT) is one of the most common serious complications in patients with liver cirrhosis. The occurrence of PVT not only aggravates the condition of liver cirrhosis but can also cause several serious complications, such...
Clinicopathological insights and management of liver metastases: Current advances and future perspectives [0.03%]
肝转移的临床病理学见解和管理：当前进展与未来展望
Noura A A Ebrahim,Thoraya A Farghaly,Ahmed Abdo El-Sherif et al.
Noura A A Ebrahim et al.
Liver metastases are a leading contributor to cancer-related illness and death, occurring far more frequently than primary liver tumors. Their management remains highly challenging due to the complexity of disease behavior and the need for ...