Protective Effects of Spirulina Supplementation on Chondrocytes Under Moderate Acute Dynamic Compression [0.03%]
螺旋藻对中度急性动态压缩下软骨细胞的保护作用
Nadia Golestani,Saba Rafieian,Stephen D Waldman et al.
Nadia Golestani et al.
ObjectiveTo determine the influence of Spirulina supplementation on the response of bovine chondrocytes to mechanical compression with respect to extracellular matrix dynamics (proteoglycan and collagen) and inflammation [nitric oxide (NO)]...
What are the Chances of MACI Approval in the United States? A Deep Dive into the Insurance Authorization Data [0.03%]
MACI在美国获批的可能性有多大？深入分析保险授权数据
Parker A Cavendish,Eric M Milliron,Clayton J Peterson et al.
Parker A Cavendish et al.
ObjectiveTo describe recent trends in US MACI (autologous cultured chondrocytes on porcine collagen membrane) insurance approval rates, including the impact of defect location and the number of defects.DesignMyCartilageCare case management ...
Ernst B Hunziker,Nahoko Shintani,Marius J B Keel
Ernst B Hunziker
ObjectiveLesions of adult articular cartilage occur due to trauma or disease, such as osteoarthritis. If they do not penetrate the subchondral bone, they are called partial-thickness defects (PTDs), which are believed not to heal. However, ...
Quantitative Magnetic Resonance Spectroscopy and T2 Mapping for Evaluating Knee Subchondral Bone and Cartilage Changes in Chronic Kidney Disease [0.03%]
慢性肾脏疾病患者膝关节软骨和软骨下骨变化的定量磁共振波谱及T2图评估研究
Shih-Wei Chiang,Yu-Juei Hsu,Yi-Jen Peng et al.
Shih-Wei Chiang et al.
ObjectiveTo investigate water and lipid composition changes in knee subchondral bone marrow and cartilage in chronic kidney disease (CKD) patients compared with age- and sex-matched healthy controls using magnetic resonance spectroscopy (MR...
Chondrocyte Senescence in Osteoarthritis: Potential Targets and Pharmacological Interventions [0.03%]
骨关节炎软骨细胞衰老：潜在靶点与药物干预
Dunyong Tan,Jiawei Guo,Tianyu Wang et al.
Dunyong Tan et al.
PurposeThis review aims to elucidate the mechanisms underlying chondrocyte senescence in osteoarthritis (OA) from 4 core perspectives: extracellular inflammation, mechanical overload and stress, intracellular metabolic and signaling dysregu...
Uncovering the Impact of Center of Rotation of Angulation Location on High Tibial Osteotomy in Knee Osteoarthritis: A Potential Pathway for Improved Outcomes [0.03%]
角胫骨高位截骨术中旋转中心定位对膝关节骨关节炎的影响：改善预后的潜在途径
Yannick Janssen,H Chien Nguyen,Roel J H Custers et al.
Yannick Janssen et al.
ObjectiveLower limb malalignment accelerates the progression of knee osteoarthritis (KOA). Knee realignment osteotomy is a well-established treatment for unicompartmental KOA with malalignment. Traditional planning in KOA patients corrects ...
Minced Cartilage Transplantation Demonstrated Improved Cartilage Repair Healing Compared to Bone Marrow Aspirate Concentrate on Hyaluronic Acid (HA-BMAC) for Full-Thickness Knee Cartilage Lesions: Clinical And Biological Outcomes in a Matched Cohort Study [0.03%]
膝关节全层软骨缺损微粒软骨移植和透明质酸骨髓浓集相比修复效果更佳：匹配队列研究的临床及生物学结果
Martin Lind,Torsten Grønbech Nielsen,Bjørn Borsøe Christensen et al.
Martin Lind et al.
PurposeTo compare the clinical and biological outcomes of minced autologous cartilage transplantation versus hyaluronic acid-based scaffold with bone marrow aspirate concentrate (HA-BMAC) in the treatment of full-thickness cartilage lesions...
Effect of Synovial Cell Fractionation on Tenascin-C Expression in Chondrocytes Under Coculture [0.03%]
滑膜细胞分选对软骨细胞共培养中岩藻糖黏蛋白表达的影响
Gai Kobayashi,Takahiro Iino,Kyoko Imanaka-Yoshida et al.
Gai Kobayashi et al.
ObjectiveThis study investigated the effect of synovial cell fractionation on tenascin-C (TNC) expression in chondrocytes by coculturing human chondrocytes with synovial cells derived from osteoarthritis (OA) patients.DesignHuman cartilage ...
Collagen Type II-Derived Telopeptides Cause Tissue Damage in Human Cartilage Cultures Established From Total Arthroplasty [0.03%]
来源于人工关节置换术的人类软骨培养中的II型胶原末端肽引起组织损伤
Jiamin Mao,Quanming Wang,Yubo Lu et al.
Jiamin Mao et al.
ObjectiveTo determine whether telopeptides of collagen type II could induce osteoarthritic tissue damage via receptor for the native protein by using human articular cartilage.MethodsCartilage slices were harvested from patients receiving t...
Assessment of the Correlation between Macroscopic ICRS Grading and Histopathological OARSI Scoring in Osteoarthritic Cartilage: An Ex-Vivo Analysis [0.03%]
基于离体软骨分析的ICRS宏观分级与OARSI病理学评分相关性的评估研究
Gavish Uppal,Tarun Goyal,Anup Kumar et al.
Gavish Uppal et al.
AimsPrecise evaluation of cartilage damage is essential for the better management of osteoarthritis and treatment of articular cartilage. For accurate evaluation of cartilage damage, direct visual and/or histological assessment of articular...