Adiponectin and Glucocorticoids Modulate Risk for Preterm Birth: The Healthy Start Study [0.03%]
脂联素和糖皮质激素调节早产风险：健康起点研究
Gabriella Mayne,Peter E DeWitt,Jennifer Wen et al.
Gabriella Mayne et al.
Purpose: Adiponectin is a potent uterine tocolytic that decreases with gestational age, suggesting it could be a maternal metabolic quiescence factor. Maternal stress can influence preterm birth risk, and adiponectin leve...
Urolithiasis Causes Osteoporosis in Asians: Genetic Evidence from Mendelian Randomization and Pathway Analysis [0.03%]
尿路结石导致亚洲人骨质疏松：孟德尔随机化和路径分析的遗传证据
Zijie Zhou,Haoying Xu,Jiehui Fu et al.
Zijie Zhou et al.
Background: It is an indisputable fact that patients with urolithiasis are prone to osteoporosis (OP), but the specific mechanism of their association is unclear. Previous studies have focused on the mediation of environm...
Targeting the Manifestations of Subclinical and Overt Hypothyroidism Within the Hippocampus [0.03%]
靶向亚临床和显性甲状腺功能减退海马表现症状
Joanne F Rovet
Joanne F Rovet
Background: The past decade has witnessed a surge of articles describing the neurocognitive sequelae and associated structural and functional brain abnormalities of patients with overt (OH) and subclinical hypothyroidism ...
Efficacy and safety of multikinase inhibitors for patients with refractory thyroid cancer: Systematic review and network meta-analysis [0.03%]
甲状腺癌多靶点激酶抑制剂疗效和安全性的系统评价和网状Meta分析
Ren Jing,Nan Wu,Yang Wu et al.
Ren Jing et al.
Context: Multikinase inhibitors (MKIs) improve the treatment of refractory thyroid cancer, included radioactive iodine-refractory differentiated thyroid cancer (RAIR-DTC) and advanced medullary thyroid carcinoma (aMTC). ...
Inadequate Glucagon Suppression During OGTT in prediabetes: A Systematic Review and Meta-Analysis [0.03%]
糖尿病前期口服葡萄糖耐量试验中胰高血糖素抑制不足的系统评价和 meta 分析
Lina Chang,Ying Liu,Yian Gu et al.
Lina Chang et al.
Context: Glucagon plays a role in the development of type 2 diabetes, yet its role in prediabetes (preDM) remains uncertain. Objective: ...
Rozan Abu-Nejem,Tamara S Hannon
Rozan Abu-Nejem
Youth-onset type 2 diabetes (T2D) is increasing around the globe. The increased disease burden of youth-onset T2D portends substantial consequences for the health outcomes of young people and for health care systems. The pathophysiology of ...
Clinical and genetic characteristics of congenital hyperinsulinism in Norway: A nationwide cohort study [0.03%]
挪威先天性高胰岛素血症的临床和遗传特征全国队列研究
Christoffer Drabløs Velde,Janne Molnes,Siren Berland et al.
Christoffer Drabløs Velde et al.
Purpose: Congenital hyperinsulinism (CHI) is a rare, monogenic disease characterized by excessive insulin secretion. We aimed to evaluate all probands with suspected CHI in Norway registered over the past two decades. ...
Antoinette Cameron-Pimblett,Clementina La Rosa,Melanie C Davies et al.
Antoinette Cameron-Pimblett et al.
Context: Diabetes mellitus (DM) risk factors in Turner Syndrome (TS) may include autoimmunity, obesity, beta-cell dysfunction, genetic predisposition and insulin resistance (IR). ...
Fetal/maternal-determined birth weight and adulthood type 2 diabetes and its subtypes: a Mendelian randomization study [0.03%]
基于孟德尔随机化研究的胎儿源性及母体源性出生体重与成人2型糖尿病及其亚型的关系
Wenxiu Wang,Wendi Xiao,Zimin Song et al.
Wenxiu Wang et al.
Background: Lower birth weight (BW) might increase the risk of adulthood type 2 diabetes, but its associations with the highly heterogeneous type 2 diabetes subtypes remain to be studied. In addition, whether the associat...