Diagnosis of Acromegaly [0.03%]
Divya Yogi-Morren,Philippe Chanson
Divya Yogi-Morren
The clinical presentation of acromegaly reflects systemic effects of chronic GH and IGF-I excess. Diagnostic delay frequently ranges from 6 to 10 years. While classical manifestations such as acral enlargement and facial coarsening are diag...
Quick Determination of Adrenal Venous Selectivity for the Determination of Unilateral Aldosteronism [0.03%]
Celso E Gomez-Sanchez
Celso E Gomez-Sanchez
Outcome Of First-Line Chemotherapy For Anaplastic Thyroid Cancer - A Multicenter Registry Analysis [0.03%]
Katharina Elisabeth Graf,Pia Adam,Felix Megerle et al.
Katharina Elisabeth Graf et al.
Context: Prognosis of anaplastic thyroid cancer (ATC) remains poor. In the absence of immediately actionable molecular alterations, guidelines recommend multimodal therapy including radiotherapy and cytotoxic chemotherapy...
Impact of pituitary adenoma histological subtype on remission and disease control in acromegaly [0.03%]
Alexandra Monnot,Mirela-Diana Ilie,Camille Sergeant et al.
Alexandra Monnot et al.
Introduction: Acromegaly results from different histological subtypes of pituitary adenomas, mainly pure GH-secreting adenomas (densely or sparsely granulated) and GH-PRL adenomas. Data on the impact of histological subty...
Endocrine Characteristics in Bardet Biedl Syndrome from a Large Single-Centre Paediatric Multidisciplinary Clinic [0.03%]
Rachel S Varughese,Divya Pujari,Elizabeth Hatton et al.
Rachel S Varughese et al.
Objective: Bardet-Biedl syndrome (BBS) is a rare genetic ciliopathy characterised by obesity, rod-cone dystrophy, polydactyly, hypogonadism, cognitive impairment and renal abnormalities. Additional endocrine associations ...
Karl E Friedl,Bradley C Nindl,Adam W Potter
Karl E Friedl
Low circulating testosterone in physically stressed populations is frequently interpreted as evidence of hypogonadism or intrinsic gonadal dysfunction. However, convergent data from military field studies, endurance athletes, and competitiv...
Artificial Intelligence-Enabled Analysis of Radiology Reports: Epidemiology and Outcomes of Incidental Thyroid Findings [0.03%]
Felipe Larios,Mariana Borras-Osorio,Yuqi Wu et al.
Felipe Larios et al.
Context: Incidental thyroid findings (ITFs) are increasingly detected on imaging performed for non-thyroid indications. Their prevalence, features, and consequences remain undefined. ...
Luiz Eduardo Wildemberg,Mônica R Gadelha
Luiz Eduardo Wildemberg
Patient responses to medical therapy for acromegaly are variable. Adenoma features, including histologic characteristics and receptor density, are closely associated with distinct clinical behavior and therapeutic outcomes. Densely granulat...
The effectiveness of hormonal treatment to improve reproductive outcomes in normo-gonadotropic men with abnormal semen parameters: Results of two linked systematic reviews [0.03%]
Kristin Konnyu,Mari Imamura,Jemma Hudson et al.
Kristin Konnyu et al.
Context: Growing numbers of international guidelines recommend hormonal treatment for normogonadotropic men with abnormal semen parameters, despite uncertain effects on fertility outcomes. ...