Is There an Association Between Endometriosis, Early Menopause, and Cardiovascular Disease? [0.03%]
子宫内膜异位症、早期绝经和心血管疾病有关联吗？
Johnny S Younis,Hugh S Taylor
Johnny S Younis
Large-scale studies show endometriosis linked to earlier menopause onset. Recent research targeting women with laparoscopically diagnosed endometriosis found an increase in cases of early natural menopause. Furthermore, recent large-scale c...
Congenital hyperinsulinism and novel KDM6A duplications -resolving pathogenicity with genome and epigenetic analyses [0.03%]
遗传性高胰岛素血症与KDM6A的新 duplication-通过基因组和表观遗传分析确定致病性
Jonna M E Männistö,Jasmin J Hopkins,Thomas I Hewat et al.
Jonna M E Männistö et al.
Context: Hyperinsulinemic hypoglycemia (HI) can be the presenting feature of Kabuki syndrome (KS), which is caused by loss-of-function variants in KMT2D or KDM6A. As these genes play a critical role in maintaining methyla...
The Association Between Obesity and Polycystic Ovary Syndrome: An Epidemiologic Study of Observational Data [0.03%]
基于观察数据的肥胖与多囊卵巢综合征关系的流行病学研究
Mina Amiri,Sana Hatoum,Dawnkimberly Hopkins et al.
Mina Amiri et al.
Background: Polycystic ovary syndrome (PCOS) is a common female cardiometabolic-reproductive disorder. It is unclear whether the global obesity epidemic is impacting the high PCOS prevalence. ...
Gut microbial changes associated with obesity in youth with type 1 diabetes: a Pilot Study [0.03%]
肥胖1型糖尿病青年肠道微生物变化：一项试点研究
Heba M Ismail,Dimuthu Perera,Rabindra Mandal et al.
Heba M Ismail et al.
Context: Obesity is prevalent in type 1 diabetes (T1D) and is problematic with higher risk for diabetes complications. It is unknown to what extent gut microbiome changes are associated with obesity and T1D. ...
Data-driven Cluster Analysis Reveals Increased Risk for Severe Insulin-Deficient Diabetes in Black/African Americans [0.03%]
数据驱动的聚类分析揭示黑人/非裔美国人患严重胰岛素缺乏型糖尿病的风险增加
Brian Lu,Peng Li,Andrew B Crouse et al.
Brian Lu et al.
Context: Diabetes is a heterogenic disease and distinct clusters have emerged, but the implications for diverse populations have remained understudied. Ob...
Effectiveness of Different Treatment Modalities in Initial and Chronic Phases of Thyroid Eye Disease: A Systematic Review With Meta-analysis [0.03%]
甲状腺眼病初始阶段和慢性阶段不同治疗方法有效性的系统评价及meta分析
Jose Mario Alves Junior,Wanderley Bernardo,Danilo Villagelin
Jose Mario Alves Junior
Background: Thyroid eye disease (TED), a common extrathyroidal manifestation of Graves disease, poses significant management challenges due to potential disfigurement, visual impairment, and decreased quality of life. Unc...
Novel biomarkers reveal mismatch between tissue and serum thyroid hormone status in amiodarone-induced hyperthyroidism [0.03%]
新型生物标志物揭示胺碘酮所致甲状腺功能亢进症中组织与血清甲状腺激素状态不匹配现象
Richárd Sinkó,Mónika Katkó,Géza Tóth et al.
Richárd Sinkó et al.
Context: Serum TSH and thyroid hormone (TH) levels are routine markers of thyroid function. However, their diagnostic performance is limited under special conditions, e.g. in amiodarone-induced hyperthyroidism (AIH). Such...
Gut-Microbiota-Related Metabolite Phenylacetylglutamine and Risk of Incident Coronary Heart Disease among Women [0.03%]
女性胆碱代谢产物苯乙酰谷氨酰胺与冠心病发病风险关系的前瞻性研究
Yoriko Heianza,Saumya Tiwari,Xuan Wang et al.
Yoriko Heianza et al.
Context: Phenylacetylglutamine (PAGln) is a novel metabolite derived from gut microbial metabolism of dietary proteins, specifically phenylalanine, which may be linked to risks of adverse cardiovascular events. ...
Cord Blood Fetuin-B, Fetal Growth Factors and Lipids in Gestational Diabetes Mellitus [0.03%]
妊娠糖尿病婴儿脐带血胎蛋白B、生长因子及脂质水平
Wen-Juan Wang,Hua He,Fang Fang et al.
Wen-Juan Wang et al.
Context/objective: Fetuin-B is a hepatokine/adipokine implicated in glucose homeostasis and lipid metabolism. We sought to assess whether cord blood fetuin-B levels are altered in gestational diabetes mellitus (GDM) and t...