Deficiency of Peptidylglycine-alpha-amidating Monooxygenase, a Cause of Sarcopenic Diabetes Mellitus [0.03%]
肽基甘氨酸α酰胺酶单加氧酶缺乏症可致糖尿病性肌萎缩
Alice Giontella,Mikael Åkerlund,Kevin Bronton et al.
Alice Giontella et al.
Context: Peptidylglycine-α-amidating monooxygenase (PAM) is a critical enzyme in the endocrine system responsible for activation, by amidation, of bioactive peptides. ...
Prevalence of Metabolic Dysfunction-associated Steatotic Liver Disease and Cardiometabolic Risk Factor in US Adolescents [0.03%]
美国青少年代谢功能异常性肝脂肪病的患病率及其心血管代谢危险因素分布状况
Xiaoyan Zheng,Dongying Zhao,Liwei Wang et al.
Xiaoyan Zheng et al.
Context: Metabolic dysfunction-associated steatotic liver disease (MASLD) is widespread worldwide, and a strong link between MASLD and cardiometabolic risk factors (CMRFs) was emphasized. ...
GFR decline predicts total mortality and mediates the effect of tryptophan metabolism on death risk in type 2 diabetes [0.03%]
估算肾小球滤过率下降可预测2型糖尿病患者的全因死亡风险，并介导色氨酸代谢影响死亡风险的作用
Olga Lamacchia,Claudia Menzaghi,Massimiliano Copetti et al.
Olga Lamacchia et al.
Context: The independent role of glomerular filtration rate (GFR) decline in shaping the risk of mortality in people with type 2 diabetes has only been partially addressed. ...
Response to Letter to the Editor from Hao and Xue: "Checkpoint Inhibitor-Associated Autoimmune Diabetes Mellitus Is Characterized by C-peptide Loss and Pancreatic Atrophy" [0.03%]
对郝和薛的来信“检查点抑制剂相关自身免疫糖尿病以C肽缺失和胰腺萎缩为特征”的回复
Linda Wu,Matteo Salvatore Carlino,David Alexander Brown et al.
Linda Wu et al.
Determinants of Health Care Dissatisfaction among a US Population-based Cohort of Women with Polycystic Ovary Syndrome [0.03%]
美国多囊卵巢综合征女性人群队列的医疗不满意的影响因素分析
Jacob P Christ,Rachel Blank,Heather G Huddleston
Jacob P Christ
Context: The 2018 International Evidence Based Guidelines (IEBG) for PCOS were created, in part, in response to poor patient satisfaction on international surveys. Patient satisfaction in the US, before and after these gu...
Associations of BMI growth rates and body composition with cardiometabolic risks in Chinese preschool children [0.03%]
中国学龄前儿童体质指数增长速率及体成分与心血管代谢风险的关系
Zijun Liao,Jing Wang,Yiren Chen et al.
Zijun Liao et al.
Objective: To examine the relationship between body mass index (BMI) growth rates, body composition, and cardiometabolic markers in preschool children. Me...
β-cell dedifferentiation in HOMA-βlow and HOMA-βhigh subjects [0.03%]
HOMA-βlow和HOMA-βhigh受试者的β细胞去分化
Fuyun Kang,Zhuo Zhang,Hui Fu et al.
Fuyun Kang et al.
Context: β-cell dedifferentiation ratio is increased in type 2 diabetes; but its direct link to in vivo β-cell function in human remains unclear. Object...
Cabozantinib plus ipilimumab/nivolumab in patients with previously treated advanced differentiated thyroid cancer [0.03%]
卡博替尼联合伊匹木单抗/纳武利尤单抗治疗经治的晚期分化型甲状腺癌患者
Bhavana Konda,Eric J Sherman,Erminia Massarelli et al.
Bhavana Konda et al.
Background: This investigator-initiated phase II trial aimed to evaluate the efficacy of cabozantinib in combination with nivolumab and ipilimumab (CaboNivoIpi) in previously treated patients with radioactive iodine (RAI)...
Approach to the Pediatric Patient with Glucocorticoid-Induced Osteoporosis [0.03%]
儿童糖皮质激素性骨质疏松症患者的治疗方案
Leanne M Ward,Sarah Bakhamis,Khaldoun Koujok
Leanne M Ward
Glucocorticoid (GC) therapy remains the cornerstone of treatment for many conditions of childhood and an important cause of skeletal and endocrine morbidity. Here, we discuss cases that bring to life the most important concepts in the manag...
Increased risk of chronic kidney disease after total thyroidectomy: A nationwide matched cohort study [0.03%]
甲状腺全切术后慢性肾脏病风险增加：全国匹配队列研究
Rasmus Reinke,Sebastian Udholm,Christian Fynbo Christiansen et al.
Rasmus Reinke et al.
Background: Development of hypoparathyroidism (hypoPT) after total thyroidectomy (TT) may increase the risk of kidney-related morbidity. We aimed to examine the risk of hypoPT and chronic kidney disease (CKD) in patients ...