Association of Glucose Response Shape in OGTT With Markers of Pancreatic Health and Inflammation Across Diverse Ages [0.03%]
口服葡萄糖耐量试验的血糖动力学与各年龄段胰岛素储备和炎症标志物之间的关系
Cindy J Hernandez-Moreno,Bonita Falkner,Scott W Keith et al.
Cindy J Hernandez-Moreno et al.
Context: The shape of glucose response in the oral glucose tolerance test (OGTT) is a biomarker for pancreatic β-cell health. A biphasic response is deemed metabolically healthier compared to monophasic, while persistent...
A Global Approach to the Long-Term Follow-up of 17 Families with Bilateral Macronodular Adrenal Disease [0.03%]
长期随访17例双侧肾上腺巨结节疾病的全球性方法
Helaine Laiz Silva Charchar,Guilherme Asmar Alencar,Beatriz Marinho de Paula Mariani et al.
Helaine Laiz Silva Charchar et al.
Context: Bilateral macronodular adrenocortical disease (BMAD) is a rare and often underdiagnosed cause of adrenal Cushing's syndrome (CS), with manifestations ranging from mild autonomous cortisol secretion (MACS) to over...
Identification of gut microbiome signatures and metabolites associated with albuminuria in type 2 diabetes [0.03%]
2型糖尿病患者尿白蛋白的肠道菌群标志物和代谢产物识别研究
Yi-Ting Lin,Sergi Sayols-Baixeras,Tiscar Graells et al.
Yi-Ting Lin et al.
Context: Type 2 diabetes is a growing global concern with serious complications, including kidney damage and cardiovascular morbidity and mortality. Monitoring albuminuria, which is associated with these complications, is...
When the fog lingers: persistent cognitive and emotional burden in patients with a prolactinoma despite disease control [0.03%]
当迷雾徘徊时：肢端肥大症患者认知和情感负担的持续存在及其对疾病控制的影响
Stefan Matei Constantinescu,Dominique Maiter
Stefan Matei Constantinescu
Blood plasma proteome-wide association study implicates new proteins in type 2 diabetes mellitus pathogenesis [0.03%]
血浆蛋白质组范围的关联研究揭示了2型糖尿病发病机制中的新蛋白
Yang Yang,Jia-Hao Wang,Hao-An Wang et al.
Yang Yang et al.
The pathophysiological mechanisms underlying type 2 diabetes mellitus (T2DM) remain incompletely understood, and the disease continues to impose a substantial burden on global health. In this study, we integrated the data from the largest g...
Compartment-Specific Metabolic Alterations to Insulin Reflect Adiposity-Driven Variation and Predict Type 2 Diabetes [0.03%]
根据脂肪量驱动的变异而针对胰岛素作出适应的隔室特异性代谢变化可预测2型糖尿病
Magdalena Sevilla-González,Paul A Hanson,Jesse Islam et al.
Magdalena Sevilla-González et al.
Context: The metabolic mechanisms underlying insulin resistance (IR) are not fully understood. Metabolomic profiling can reveal compartment-specific variations and identify individuals at risk for type 2 diabetes (T2D). ...
Efficacy and Safety of Radiotherapy and Systemic Treatments in Adrenocortical Carcinoma: Systematic Review and Meta-Analysis [0.03%]
肾上腺皮质癌放疗和系统性治疗疗效及安全性的系统评价和meta分析
Anita Pfeffer,Nóra Beke,Dorottya Bakó et al.
Anita Pfeffer et al.
Context: Adrenocortical carcinoma (ACC) is a rare, aggressive malignancy with a high recurrence and mortality rate even after complete resection. Therefore, intensification of adjuvant therapies is crucial, though their e...
Glucagon: The Arab Phoenix of the Complex Pathophysiology of Type 2 Diabetes [0.03%]
glucagon：复杂2型糖尿病病理生理学中的阿拉伯凤凰
Stefano Del Prato,Riccardo C Bonadonna
Stefano Del Prato
Response to Letter to the Editor from Perros: Comprehensive Comparisons of Different Treatments for Active Graves Orbitopathy: A Systematic Review and Bayesian Model-Based Network Meta-Analysis [0.03%]
Perros来信的答复：活跃期Graves眼病的不同治疗方法的全面比较：系统评价和基于模型的网络meta分析
Yanlin Xu,Ruikang Liu,Liying Huang et al.
Yanlin Xu et al.