Development of 24-hour rhythms in cortisol secretion across infancy: a systematic review and meta-analysis of individual participant data [0.03%]
婴儿皮质醇分泌昼夜节律发展的系统评价和个体患者数据的meta分析
Laura Kervezee,Michelle Romijn,Kirsten N G van de Weijer et al.
Laura Kervezee et al.
Background: In adults, cortisol levels show a pronounced 24-hour rhythm with a peak in the early morning. It is unknown at what age this early-morning peak in cortisol emerges during infancy, hampering the establishment o...
Insulin sensitivity and skeletal muscle mitochondrial respiration in Black and White women with obesity [0.03%]
肥胖黑人和白人女性的胰岛素敏感性和骨骼肌线粒体呼吸作用
Justine M Mucinski,Giovanna Distefano,John Dubé et al.
Justine M Mucinski et al.
Objectives: Non-Hispanic black women (BW) have a greater risk of type 2 diabetes (T2D) and insulin resistance (IR) compared to non-Hispanic white women (WW). The mechanisms leading to these differences are not understood,...
Sex-specific association of chronic proton pump inhibitor use with reduced bone density and quality [0.03%]
胃质子泵抑制剂的长期使用会降低男性骨密度和骨质量
Fabio Bioletto,Alessia Pusterla,Federica Fraire et al.
Fabio Bioletto et al.
Context: Chronic use of proton pump inhibitors (PPIs) has been associated with an increase in bone fragility. However, evidence on the effect of chronic PPI use on bone density is conflicting, and data on bone microarchit...
Total and regional fat-to-muscle mass ratio in relation to all-cause and cause-specific mortality in men and women [0.03%]
全身和区域脂肪与肌肉质量比与全因及特定原因死亡率之间的关系：一项针对男性和女性的研究
Minzhi Xu,Yanhong Gong,Xiaoxv Yin
Minzhi Xu
Context: Fat-to-muscle mass ratio (FMR) has been considered a potentially useful indicator for assessing disease risk. However, the association between FMR and risk of death remains inconclusive. ...
Maria Marengo,Claire Briet,Mathilde Munier et al.
Maria Marengo et al.
Introduction: The clinical manifestations of Cushing's syndrome are variable, but an important number of patients present a metabolic syndrome, strongly associated with hepatic steatosis. The aim of this study was to dete...
Inflammation and prediction of death in type 2 diabetes. Evidence of an intertwined link with tryptophan metabolism [0.03%]
糖尿病患者的炎症与死亡预测。氨基酸代谢的相互交织关系证据
Claudia Menzaghi,Antonella Marucci,Mario Mastroianno et al.
Claudia Menzaghi et al.
Objective: To study whether inflammation is associated with and helps predict mortality risk in patients with type 2 diabetes. To explore the intertwined link between inflammation and tryptophan metabolism on death risk. ...
Association between serum remnant cholesterol level and metabolic dysfunction-associated steatotic liver histology [0.03%]
血清残余胆固醇水平与代谢失调相关脂肪肝病理变化的关联研究
Teruki Miyake,Shinya Furukawa,Bunzo Matsuura et al.
Teruki Miyake et al.
Context: Estimated remnant cholesterol (Rem-C) level, a risk factor for cardiovascular disease (CVD), is associated with metabolic dysfunction-associated steatotic liver disease (MASLD) diagnosed via ultrasonography. Howe...
The impact of time-restricted eating on beta-cell function in adults with type 2 diabetes: a randomized cross-over trial [0.03%]
时间限制性饮食对2型糖尿病成人β细胞功能的影响：交叉过实验研究
Caroline Kaercher Kramer,Bernard Zinman,Denice S Feig et al.
Caroline Kaercher Kramer et al.
Objective: Time-restricted eating (TRE) which consists of restricting the eating window to typically 4-8h (while fasting for the remaining hours of the day) has been proposed as a non-pharmacological strategy with cardio-...
Iron status correlates strongly to Insulin Resistance among U.S. adults: A nationwide population-base study [0.03%]
美国成年人群中铁状态与胰岛素抵抗密切相关的一项基于全国人口的流行病学研究
Xue Liu,Yuhao Zhang,Yuwei Chai et al.
Xue Liu et al.
Background: Evidence on the link between iron status markers and insulin resistance (IR) is limited. We aimed to explore the relationship between iron status and IR among U.S. adults. ...
Christiaan F Mooij,Nitash Zwaveling-Soonawala,Jacquelien J Hillebrand et al.
Christiaan F Mooij et al.
Graves' disease (GD) is the leading cause of hyperthyroidism in children. However, compared to adults GD in children is a rare condition. In a recent guideline issued by the European Thyroid Association the diagnostic evaluation and treatme...