Proposed Denosumab Biosimilar SB16 vs Reference Denosumab in Postmenopausal Osteoporosis: Phase 3 Results Up to Month 12 [0.03%]
狄诺塞麦类似药SB16与原研狄诺塞麦治疗绝经后骨质疏松症：一项12个月的三期临床研究结果
Bente Langdahl,Yoon-Sok Chung,Rafal Plebanski et al.
Bente Langdahl et al.
Context: SB16 is a proposed biosimilar to reference denosumab (DEN; brand name: Prolia). Objective: This phase 3 randomized, double-bli...
Predictors of cardiovascular disease in individuals with dysbetalipoproteinemia: a prospective study in the UK Biobank [0.03%]
基于英国生物样本库的异常β脂蛋白血症患者心血管疾病危险因素的前瞻性研究
Martine Paquette,Mark Trinder,Simon-Pierre Guay et al.
Martine Paquette et al.
Background: Dysbetalipoproteinemia (DBL) is a disorder of remnant cholesterol metabolism associated with a severe risk of atherosclerotic cardiovascular disease (ASCVD). ...
Ticiana Paes,Jacobo Buelvas Mebarak,John C Magnotto et al.
Ticiana Paes et al.
Context and objective: The genetic profile of prolactinomas remains poorly understood. Our objective is to identify somatic genetic alterations associated with prolactinomas and to report the identification of an activati...
Bone Microarchitecture in Older Men with Type 2 Diabetes: The Importance of Bone Size [0.03%]
骨微结构与2型糖尿病男性患者的重要性及骨大小的关系
Julien Paccou
Julien Paccou
Comparison of patients with familial chylomicronemia syndrome and multifactorial chylomicronemia syndrome [0.03%]
家族性低脂蛋白血症与多因素引起的乳糜微粒血症患者的比较分析
Catherine M Spagnuolo,Jian Wang,Adam D McIntyre et al.
Catherine M Spagnuolo et al.
Context: Patients with rare familial chylomicronemia syndrome (FCS) and relatively common multifactorial chylomicronemia syndrome (MCS) both express severe hypertriglyceridemia, defined as plasma triglyceride concentratio...
Early Pregnancy Plasma Per- and Polyfluoroalkyl Substances (PFAS) and Maternal Midlife Adiposity [0.03%]
孕期血浆全氟和多氟烷基物质(PFAS)与产妇中年期肥胖的关系
Jordan A Burdeau,Briana J K Stephenson,Jorge E Chavarro et al.
Jordan A Burdeau et al.
Context: Evidence suggests that exposure to per- and polyfluoroalkyl substances (PFAS) increases the risk of developing cardiometabolic disease risk factors. Limited research has evaluated associations between PFAS, asses...
Clinical Features and HLA Genetics Differ in Children at Type 1 Diabetes Onset by Hispanic Ethnicity [0.03%]
ethnicity影响1型糖尿病患儿临床特征和HLA遗传学的区别
Kagan E Karakus,Theodore Fleury,Erin E Baschal et al.
Kagan E Karakus et al.
Context: Type 1 diabetes incidence continues to increase in children, especially among Hispanic Whites (HW). Objective: We investigated...
Serum steroid profiling in the diagnosis of adrenocortical carcinoma: a prospective cohort study [0.03%]
皮质癌诊断中的雄性激素谱系特征：前瞻性队列研究
Kai Yu,Shobana Athimulam,Jasmine Saini et al.
Kai Yu et al.
Context: Guidelines suggest performing urine steroid profiling in patients with indeterminate adrenal tumors to make a noninvasive diagnosis of adrenocortical carcinoma (ACC). However, urine steroid profiling is not widel...
Effects of atrial fibrillation screening according to thyroid function: Post-hoc analysis of the randomized LOOP study [0.03%]
根据甲状腺功能的房颤筛查的效果-LOOP研究的事后分析
Daniel Camillo Spona,Diana My Frodi,Lucas Yixi Xing et al.
Daniel Camillo Spona et al.
Purpose: Subclinical thyroid dysfunction is a marker for atrial fibrillation (AF) and stroke risk. This study explored the effects of AF screening according to thyroid-stimulating hormone (TSH) levels. ...
Presentation, Management, and Outcomes of Patients with Giant Pheochromocytoma: Retrospective Cohort Study [0.03%]
巨大嗜铬细胞瘤患者的 presentation、管理及预后：回顾性队列研究
Bahar Bahrani Fard,Nasrin Nikravangolsefid,Justin W Maroun et al.
Bahar Bahrani Fard et al.
Context: Data on giant pheochromocytomas (PHEO), defined based on size ≥ 10 cm, are scarce. Objective: to compare presentation, manage...