Aldosterone and Diabetes Risk: An Association in Need of Mechanistic Insights [0.03%]
醛固酮与糖尿病风险:一种亟需机制见解的关联性问题
Justin B Echouffo-Tcheugui,Sam Dagogo-Jack
Justin B Echouffo-Tcheugui
Deciphering the Presentation and Etiologies of Hypophysitis Highlights the Need for Repeated Systematical Investigation [0.03%]
解读垂体炎的表达及病因凸显了需要进行重复系统的调查研究
Léa Miquel,Benoit Testud,Frédérique Albarel et al.
Léa Miquel et al.
Aims: Hypophysitis is defined as an inflammation of the pituitary gland and/or infundibulum. Our aim was to characterize the initial course and evolution of patients with hypophysitis according to the different etiologies...
Sex-Specific Cardiovascular Risk Factors and Treatment in Females With T2DM and CVD: Developments and Knowledge Gaps [0.03%]
糖尿病女性心血管风险因素及治疗中的性别差异:现状与知识空白
Erin S LeBlanc,Neon Brooks,Melinda Davies et al.
Erin S LeBlanc et al.
Purpose: There are large disparities in the impact of diabetes on cardiovascular disease (CVD) risk and outcomes by sex and gender. Achieving health equity requires understanding risks and medication efficacy in female pa...
Progressive 11β-Hydroxysteroid Dehydrogenase Type 2 Insufficiency as Kidney Function Declines [0.03%]
肾功能下降时逐渐出现的11β-羟基类固醇脱氢酶2型不足现象
Thomas Uslar,Andrew J Newman,Alejandra Tapia-Castillo et al.
Thomas Uslar et al.
Background: It has been postulated that chronic kidney disease (CKD) is a state of relative 11β-hydroxysteroid dehydrogenase type 2 (11βHSD2) insufficiency, resulting in increased cortisol-mediated mineralocorticoid rec...
Obesity is associated with hyperandrogenemia in a nationally-representative sample of U.S. girls aged 6-18 years [0.03%]
基于美国6-18岁女孩的肥胖与高雄激素血症相关的流行病学调查报告
Su Hee Kim,Aaron F Pannone,Mark D DeBoer et al.
Su Hee Kim et al.
Context: Studies have associated obesity with peri-pubertal hyperandrogenemia. However, these studies were performed in academic centers and could have been influenced by selection bias. ...
Diurnal cortisol profiles across pregnancy: challenges in the current state of knowledge [0.03%]
妊娠期间皮质醇的日间变化模式:目前知识体系的挑战
Rosario Pivonello,Renata S Auriemma,Chiara Simeoli et al.
Rosario Pivonello et al.
Selective Use of Radioiodine in Pediatric Thyroid Cancer - A Paradigm Shift [0.03%]
儿童甲状腺癌选择性使用放射碘治疗的范式转变
Eyal Robenshtok
Eyal Robenshtok
Apparent Saturation of Branched-Chain Amino Acid Catabolism After High Dietary Milk Protein Intake in Healthy Adults [0.03%]
健康成人摄入高牛奶蛋白后支链氨基酸分解代谢呈现饱和状态
Emily Newton-Tanzer,Sultan Nilay Can,Hans Demmelmair et al.
Emily Newton-Tanzer et al.
Context: Milk protein contains high concentrations of branched-chain amino acids (BCAA) that play a critical role in anabolism and are implicated in the onset of obesity and chronic disease. Characterizing BCAA catabolism...
Greater urinary calcium excretion is associated with diminished bone accrual in youth with type 1 diabetes [0.03%]
青少年1型糖尿病患者中更高的尿钙排泄与骨密度增加减慢有关
David R Weber,Kimberly O OBrien,Lance Ballester et al.
David R Weber et al.
Context: The adverse skeletal effects of type 1 diabetes (T1D) include deficient bone accrual and lifelong increased fracture risk. The contributors to impaired bone accrual in people with T1D are incompletely understood....
Pituitary Apoplexy: Comorbidities, Management and Outcomes. A Spanish Observational Multicenter Study [0.03%]
垂体卒中的并存病、管理和预后。西班牙多中心观察性研究
Betina Biagetti,Esteban Cordero Asanza,Carlos Pérez-López et al.
Betina Biagetti et al.
Background: Pituitary apoplexy (PA) is the paradigm of endocrine and neurosurgical emergency. Objective: To evaluate the comorbidities,...