A missense mutation in close proximity of ALS-linked PFN1 mutations causes only early-onset Paget's disease of bone [0.03%]
PFN1错义突变导致仅发生早发性骨 Paget 病
Rou Weng,Xiaoxiang Li,Hua Yue et al.
Rou Weng et al.
Context: Paget's disease of bone (PDB) is a metabolic disorder characterized by abnormal osteoclast activation. Recently, mutations in the PFN1 gene, which encodes Profilin 1, an actin-binding protein controlling actin dy...
Hair Cortisone Levels and the Metabolic Syndrome: Stronger Links in Younger Compared to Older Adults [0.03%]
头发皮质醇水平和代谢综合征：与年轻成人相比在年老成人中联系更弱
Susanne Kuckuck,Robin Lengton,Julius März et al.
Susanne Kuckuck et al.
Background: The striking link between Cushing's syndrome, the metabolic syndrome (MetS), and cardiovascular disease suggests that long-term exposure to high glucocorticoid levels catalyzes cardiometabolic deterioration. H...
Response to Letter to the Editor From Yan and Chang: "Long-Term Non-skeletal Complications in Patients with Thyroid Cancer and Hypoparathyroidism Post-total Thyroidectomy" [0.03%]
对 yan 和 chang 来信的回复：“甲状腺癌患者全切除术后长期非骨骼并发症”
Eu Jeong Ku,Jooyoung Lee,Won Sang Yoo et al.
Eu Jeong Ku et al.
Circulating Non-Esterified Fatty Acids in Older Adults - Revisiting the Lipid-Mortality Link [0.03%]
老年人循环未酯化脂肪酸与脂质-死亡率关系的再审视
Juliane Maushagen,Susanne Rospleszcz
Juliane Maushagen
Beneficial Effects of Carbohydrate Restriction in Type 2 Diabetes Can Be Traced to Changes in Hepatic Metabolism [0.03%]
碳水化合物限制对2型糖尿病的益处可追溯到肝脏代谢的变化
Barbara A Gower,Marian L Yurchishin,Amy M Goss et al.
Barbara A Gower et al.
Context: Carbohydrate restriction benefits metabolic health in patients with type 2 diabetes (T2D), possibly through changes in hepatic metabolism. Object...
Stable iodine intake and thyroid screening outcomes after the Fukushima Nuclear Disaster: an observational study [0.03%]
福岛核事故后稳定碘摄入与甲状腺筛查结果的观察性研究
Yoshitaka Nishikawa,Fumiya Oguro,Chiaki Suzuki et al.
Yoshitaka Nishikawa et al.
Context: Stable iodine intake is crucial in preventing thyroid cancer after radiological emergencies; however, the association between stable iodine intake and thyroid outcomes in children after the Fukushima Daiichi Nucl...
Clinical Use of Hypertonic Lactate - Current Evidence and Emerging Perspectives [0.03%]
高张乳酸钠临床应用的现有证据和展望
Mette Glavind Bülow Pedersen,Jens Hohwü Voigt,Esben Søndergaard et al.
Mette Glavind Bülow Pedersen et al.
Context: Lactate has traditionally been viewed as a metabolic byproduct associated with metabolic acidosis, exercise-induced fatigue, and cancer metabolism. However, accumulating evidence highlights its valuable role as a...
Madson Q Almeida
Madson Q Almeida
Pancreatic Cancer Screening in New-Onset and Deteriorating Diabetes: Preliminary Results from the PANDOME Study [0.03%]
新发及恶化糖尿病患者中胰腺癌筛查的初步结果——PANDOME研究
Richard C Frank,Brian Shim,Tammy Lo et al.
Richard C Frank et al.
Objective: Pancreatic cancer (PC) has a high mortality rate due to the lack of early-stage detection strategies and lethality of advanced stage presentations. New-onset diabetes (NOD) in individuals >50 years old increase...