Defining puberty and spectrum of hypogonadism in Alström Syndrome [0.03%]
Alström综合征青春期的界定及性腺功能减退谱系分布
Sadaf Ali,Qianwen Zhang,Ijeoma Anwunah et al.
Sadaf Ali et al.
Background: Alström syndrome (AS), has been extensively studied for its multi-system organ manifestations. Primary gonadal failure is well described in humans, but little is known about the intricacies of puberty and tru...
Gestational Glucose Intolerance and Risk of Obesity in Childhood and Adolescence [0.03%]
妊娠期葡萄糖耐量不良与儿童和青少年肥胖风险的关系
Jacqueline Maya,Carolin C M Schulte,Sarah Hsu et al.
Jacqueline Maya et al.
Objective: An association between in utero exposure to gestational glucose intolerance ([GGI], abnormal glucose screening without gestational diabetes), and offspring obesity has not been consistently observed. ...
Subtle cognitive impairments and psychological complaints in patients with prolactinoma despite biochemical control [0.03%]
垂体泌乳素瘤患者即便生化控制良好也存在轻微的认知功能损伤和心理主诉
Victoria R van Trigt,Cornelie D Andela,Leontine E H Bakker et al.
Victoria R van Trigt et al.
Purpose: To assess cognitive functioning and psychological complaints in patients with biochemically controlled prolactinoma. Methods: ...
Precision approaches towards diabetes prevention: towards a clustering approach with more phenotypical granularity [0.03%]
精准的糖尿病预防方法——利用更详细的表型信息进行患者分类的方法论探索
Ellen E Blaak
Ellen E Blaak
No More Free Lunch: Challenges to Mendelian Randomization Due to Sample Selection and Complex Methods [0.03%]
没有免费午餐：基于样本选择和复杂方法的孟德尔随机化面临的挑战
Tianyuan Lu,Wenmin Zhang,Fergus W Hamilton et al.
Tianyuan Lu et al.
Mendelian randomization (MR) is increasingly used in epidemiological studies to investigate causal relationships. MR depends on 3 fundamental instrumental variable assumptions: relevance, independence, and exclusion restriction. Studies oft...
Multiple or Single Endocrine Abnormalities Associated with Immune Checkpoint Inhibitors [0.03%]
与免疫检查点抑制剂相关的单个或多个内分泌异常
Fumika Kamitani,Yuichi Nishioka,Hiroki Nakajima et al.
Fumika Kamitani et al.
Background: Immune checkpoint inhibitors (ICIs) are associated with various endocrine abnormalities. However, their underlying pathophysiology remains unclear. We investigated the effect of multiple endocrine abnormalitie...
Metabolic dysfunction-associated steatotic liver disease alters fatty acid profiles in the liver and adipose tissue [0.03%]
与代谢功能异常相关的肝脂肪变性疾病的肝脏和脂肪组织中的脂质谱改变
Saana Palomurto,Kirsi A Virtanen,Vesa Kärjä et al.
Saana Palomurto et al.
Context: The alterations in systemic fatty acid (FA) metabolism in metabolic dysfunction-associated steatotic liver disease (MASLD) remain unclear. Object...
Clinical and Genetic Characteristics of Adult Nonautoimmune Hypothyroidism: A Single-Institution Study [0.03%]
成人非自身免疫性甲状腺功能减退的临床和基因特点：单中心研究
Chiho Sugisawa,Erika Uehara,Kanako Tanase-Nakao et al.
Chiho Sugisawa et al.
Purpose: Nonautoimmune hypothyroidism is characterized by hypothyroidism with negative thyroid autoantibodies with limited knowledge of its clinical and genetic characteristics. The aim was to characterize the clinical an...
Weight Trajectory Impacts Risk for Ten Distinct Cardiometabolic Diseases [0.03%]
体重变化影响10种不同的心代谢疾病的发病风险
Alison Z Swartz,Kathryn Wood,Eric Farber-Eger et al.
Alison Z Swartz et al.
Context: Repetitive bouts of weight loss and regain, termed weight cycling, may exaggerate risk for cardiometabolic disease. We previously identified that weight cyclers were likely to have prescribed medications for hype...
Levothyroxine in Pregnancy: Protective Neurodevelopmental Role Beyond Cognitive Outcomes? [0.03%]
左旋甲状腺素与妊娠：超出认知结果之外的神经发育保护作用？
Freddy J K Toloza,Sangeetha Gummalla,Spyridoula Maraka
Freddy J K Toloza