Functional Domain Mapping of TPO: Insights from Six Variants in Sudanese Kindreds with Congenital Hypothyroidism [0.03%]
TPO功能域定位：苏丹先天性甲状腺功能减退家系的六种突变的启示
Mohammad S Islam,Ruy Andrade Louzada Neto,Jessica Bouviere et al.
Mohammad S Islam et al.
Context: Congenital hypothyroidism (CH) is a leading cause of preventable intellectual disability worldwide if left untreated. Thyroid peroxidase (TPO) is a key enzyme that uses hydrogen peroxide from the DUOX/DUOXA syste...
An oral glucose tolerance test in pregnancy can serve as a valuable predictor for future diabetes [0.03%]
妊娠期口服葡萄糖耐量试验可作为将来患糖尿病的预测指标
Tal Schiller,Linoy Gabay,Oren Barak et al.
Tal Schiller et al.
Background: Adherence to screening following a pregnancy with gestational diabetes mellitus (GDM) remains low. Objective: To assess the...
Genomic Insights into Short Stature in Children Born Small for Gestational Age: A Korean Multicenter Exome Study [0.03%]
韩國多中心外顯子組研究揭示小於胎齡出生兒童身材矮小的基因組學見解
Yena Lee,Hwal Rim Jeong,Eun Young Kim et al.
Yena Lee et al.
Context: Most infants born small for gestational age (SGA) experience catch-up growth within two years, while 10‒15% remain short. The cause of this persistent growth failure remains unknown. ...
Sex steroids and women's physical performance in midlife: Findings from the Menarche-to-PreMenopause Study [0.03%]
性类固醇与女性中年体力表现：来自女童至围绝经期研究的发现
Leticia W Ribeiro,Jenny Doust,Gregore I Mielke et al.
Leticia W Ribeiro et al.
Context: Sex steroids regulate various processes in reproductive and non-reproductive systems, but relationships with physical function in females remain unclear. ...
Nikita Pozdeyev,Samantha L White,Caitlin C Bell et al.
Nikita Pozdeyev et al.
Context: Artificial intelligence (AI) has created tremendous opportunities to improve thyroid cancer care. Evidence acquisition: We use...
Polycystic Ovary Syndrome and Sleep Disturbance in Postmenopausal Women: Study of Women's Health Across the Nation [0.03%]
绝经后多囊卵巢综合征与睡眠障碍的关系：美国妇女健康纵向研究数据的分析
Snigdha Alur-Gupta,Fangbai Sun,Heping Zhang et al.
Snigdha Alur-Gupta et al.
Context: Reproductive age women with polycystic ovarian syndrome (PCOS) are more likely to have sleep apnea and experience sleep disturbances. Since sleep disturbances are known to worsen with age and to impact multiple h...
Impact of SGLT2 inhibitors on glomerular filtration in type 1 diabetes [0.03%]
SGLT2抑制剂对1型糖尿病患者肾小球滤过率的影响
Michael W Holliday Jr,Sankar D Navaneethan
Michael W Holliday Jr
Robert L Rosenfield,Daniel A Dumesic
Robert L Rosenfield
This review examines the nature of the relationship of increased adiposity to hyperandrogenic oligo-anovulatory polycystic ovary syndrome (PCOS). Most PCOS results from a "functionally typical" form of ovarian hyperandrogenism characterized...
Statins do not affect bone anabolism in older women treated with teriparatide [0.03%]
他汀类药物不影响接受特立帕肽治疗的老年妇女的骨形成作用
Cecilia Oliveri,Anastasia Xourafa,Nunziata Morabito et al.
Cecilia Oliveri et al.
Context: Teriparatide [rhPTH (1-34)] is an established anabolic agent for the treatment of severe osteoporosis. Statins, HMG-CoA reductase inhibitors, have demonstrated antiresorptive properties, but their impact on the a...