Integrative Machine Learning Approach for Predicting Resistance to First-Generation Receptor Ligands in Acromegaly [0.03%]
预测肢端肥大症一线受体配体抵抗的集成机器学习方法
Wei Lin,Songchang Shi,Yuanyuan Zheng et al.
Wei Lin et al.
Context: Acromegaly, caused by excess growth hormone (GH) and insulin-like growth factor-1 (IGF-1) due to pituitary adenomas, often necessitates first-generation somatostatin receptor ligands (fgSRLs) therapy when surgery...
Characterization of advanced RAS-driven follicular-derived thyroid cancers and review of future therapeutic avenues [0.03%]
高级RAS驱动的滤泡性衍生甲状腺癌的特征及未来治疗途径综述
Sarah Hamidi,Anastasios Maniakas,Neal S Akhave et al.
Sarah Hamidi et al.
Context: With novel RAS-targeted therapies emerging, better understanding of RAS-driven differentiated (DTC) and anaplastic (ATC) thyroid cancers is warranted. ...
Novel Inpatient Automated Self-Adjusting Subcutaneous Insulin Algorithm: Three-Year Experience. An observational study [0.03%]
住院患者自动调整的胰岛素皮下注射算法:三年观察研究经验报告
Robert J Rushakoff,Esther Rov-Ikpah,Gwendolyn Lee et al.
Robert J Rushakoff et al.
Context: Achieving inpatient glycemic control in patients who are nil per os (NPO), on enteral tube feeds (TF), or total parental nutrition (TPN) remains extremely challenging. ...
Genetics of Growth Hormone Deficiency: Insights from a Cohort of 203 Patients [0.03%]
生长激素缺乏的遗传学:来自203名患者队列的见解
Ana Cláudia Ribeiro,Eduarda Coutinho,Najeeb Syed et al.
Ana Cláudia Ribeiro et al.
Context: Growth Hormone (GH) deficiency is a rare disorder characterized by severe short stature, which can result from genetic mutations affecting hypothalamic-pituitary development and function. ...
Maturity-Onset Diabetes of the Young (MODY) in a Racially/Ethnically Diverse Pediatric Population [0.03%]
种族和民族多元的儿科人群中青年发病的成年型糖尿病(MODY)
Shilpi Relan,Guido Alarcon,Danielle Guffey et al.
Shilpi Relan et al.
Introduction: Current practice guidelines recommend considering a diagnosis of maturity-onset diabetes of the young (MODY) in patients with diabetes with an affected parent but without typical features of type 1 diabetes ...
Maternal thyroid function during pregnancy and early adolescent regional differences in cerebral gray matter morphology [0.03%]
妊娠期甲状腺功能与早期青少年大脑灰质形态的区域差异关系研究
Tessa A Mulder,Ryan L Muetzel,Robin P Peeters et al.
Tessa A Mulder et al.
Background: Thyroid hormone regulates fetal brain development. Both low and high maternal thyroid function during early pregnancy has been associated with smaller offspring total gray matter and cortex volume. However, it...
Letter to the Editor from Raschi et al.: "Endocrine adverse reactions of tyrosine kinase inhibitors in combination with immune checkpoint inhibitors" [0.03%]
Raschi等人的来信:关于酪氨酸激酶抑制剂与免疫检查点抑制剂联合应用的内分泌不良反应
Emanuel Raschi,Monia Donati,Francesco Salvo et al.
Emanuel Raschi et al.
Response to Letter to the Editor from Raschi et al.: "Endocrine adverse reactions of tyrosine kinase inhibitors in combination with immune checkpoint inhibitors" [0.03%]
对Raschi等人的来信的答复:"酪氨酸激酶抑制剂与免疫检查点抑制剂联合使用引起的内分泌不良反应"
Wen Shao,Kaiwei Yang,Difei Lu et al.
Wen Shao et al.
Koki Irie,Hajime Kato,Natsuho Adachi et al.
Koki Irie et al.
Context: Loss-of-function variants in the PHEX gene cause X-linked hypophosphatemia (XLH) with inappropriate secretion of fibroblast growth factor (FGF) 23. The PHEX protein is therefore predicted to be involved in the ph...