Debate about the Free Testosterone Hypothesis: Useful Tool or Misguided Mirage? [0.03%]
关于游离睾酮假设的争论：有用工具还是误导幻影？
Bradley D Anawalt,David J Handelsman
Bradley D Anawalt
In this debate, two clinicians discuss the merits and demerits of the free testosterone hypothesis. Although most clinical guidelines recommend the measurement of free testosterone in the evaluation for male hypogonadism (at least in men wi...
Propionate enhances the browning of adipose mesenteric tissue, reduces inflammation and increases thermogenic activity [0.03%]
丙酸促进肠系膜脂肪组织的褐变并减少炎症和增加产热活性
Sara de Castro Oliveira,Fabio Vasconcellos Comim
Sara de Castro Oliveira
Treatment of Hypothyroidism that Contains Liothyronine is Associated with Reduced Risk of Dementia and Mortality [0.03%]
含三碘甲状腺原氨酸治疗甲减与较低的痴呆和死亡风险相关
Fabyan Esberard de Lima Beltrão,Giulia Carvalhal,Vandrize Meneghini et al.
Fabyan Esberard de Lima Beltrão et al.
Introduction: Standard levothyroxine (LT4) therapy may not fully address all risks associated with hypothyroidism-especially cognitive decline, dementia, and mortality-even when TSH levels are normalized. Observational st...
The Ontogeny of Distinct Reproductive Phenotypes in Girls at Risk for PCOS During the Postmenarchal Transition [0.03%]
高PCOS风险的女孩在初潮后过渡期间distinct reproductive phenotypes不同生殖表型的发育成熟过程研究
Laura C Torchen,Apoorva Aekka,Kelly Brewer et al.
Laura C Torchen et al.
Context: Daughters of women with PCOS (PCOS-d) and girls with overweight/obesity (OW-g) have hyperandrogenemia (HA) beginning in childhood. However, other features of their early reproductive phenotypes differ, suggesting...
The Role of Cortisol Secretion in Pheochromocytomas and Paragangliomas: Clinical and Perioperative Implications [0.03%]
儿茶酚胺分泌对pheochromocytoma和paraganglioma的临床及围术期影响
Karolina Zawadzka,Jan Calissendorff,Ewelina Rzepka et al.
Karolina Zawadzka et al.
Background: Pheochromocytomas and paragangliomas (PPGLs) are tumors marked by excessive catecholamine secretion. Patients with pheochromocytomas may have elevated plasma glucocorticosteroid concentrations. This study aime...
Impact of Estrogen Replacement on Endothelial Dysfunction and Psychological Health in Women with Hypothalamic Amenorrhea [0.03%]
雌激素替代治疗对下丘脑性闭经患者内皮功能障碍和心理健康的的影响
Chrisandra L Shufelt,Nancy Safwan,Mariam Saadedine et al.
Chrisandra L Shufelt et al.
Context: Endothelial dysfunction and altered psychological measures have been identified in women with functional hypothalamic amenorrhea (FHA). Estradiol (E2) replacement, a known vasodilator, may potentially reverse vas...
Sex Hormones Mediate Intensive Lifestyle Intervention-Induced Bone Mineral Density Changes: Look AHEAD Sex Hormone Study [0.03%]
性别激素介导了强化生活方式干预诱导的骨密度变化：.look ahead性激素研究
Jiahuan Helen He,Wendy L Bennett,Jianqiao Ma et al.
Jiahuan Helen He et al.
Context: The Look AHEAD (Action in Health for Diabetes) randomized controlled trial, which compared an Intensive Lifestyle Intervention (ILI) to the Diabetes Support and Education (DSE) in people with overweight/obesity a...
Plasma Sphingolipids in Relation to Glycemia and Glucose Tolerance in People Without Diabetes [0.03%]
非糖尿病患者血浆鞘脂与血糖和葡萄糖耐量的关系
Peace Asuzu,Naser Aliye,Frankie Stentz et al.
Peace Asuzu et al.
Context: Sphingolipids have been linked to the pathogenesis of type 2 diabetes (T2D). Objective: To examine the association of plasma s...