Sustained HbA1c Improvements Over 36 Months in Youth in the Teamwork, Targets, Technology, and Tight Control (4T) Study [0.03%]
一项关于青年人在医疗团队合作、目标设定、技术应用及严格血糖控制（4T）研究中长达36个月的HbA1c改善状况的研究
Priya Prahalad,Victoria Y Ding,Dessi P Zaharieva et al.
Priya Prahalad et al.
Context: Youth with type 1 diabetes (T1D) struggle to meet and sustain hemoglobin A1c (HbA1c) targets. Youth enrolled in the Pilot 4T Study improved HbA1c by 0.5%, compared to historical controls at 1-year. ...
Genetic Risk and Transition through Preclinical Stages of Type 1 Diabetes [0.03%]
遗传风险与1型糖尿病前临床期的进展关系
Andrea K Steck,Hemang M Parikh,Taylor M Triolo et al.
Andrea K Steck et al.
Objective: Our aim was to study the influence of type 1 diabetes (T1D) genetic risk factors on the transition through preclinical stages of T1D. Methods: ...
Challenges and Opportunities for Understanding the Pathogenesis of Type 1 Diabetes: An Endocrine Society Scientific Statement [0.03%]
1型糖尿病发病机制的理解面临的挑战和机遇——内分泌学会科学声明
Aaron W Michels,Todd M Brusko,Carmella Evans-Molina et al.
Aaron W Michels et al.
The discovery of insulin transformed type 1 diabetes (T1D) from a lethal disease to a chronic health condition where individuals can lead long and productive lives. However, T1D is still associated with considerable morbidity and mortality,...
Near-adult height outcomes in patients treated with rhIGF-1 for severe growth failure: real-world IGFD Registry data [0.03%]
rhIGF-1治疗严重生长落后的患者接近成人期的身高结局：来自成人期生长障碍注册研究的真实世界数据
Marta Ramon-Krauel,Michel Polak,Mohamad Maghnie et al.
Marta Ramon-Krauel et al.
Context: The Global Increlex® Growth Forum Database (IGFD) Registry monitors real-world effectiveness and safety of recombinant human insulin-like growth factor (rhIGF-1; Increlex® [mecasermin]) treatment in children an...
FKBP5 Methylation in Adrenal Insufficiency: New Insights into Assessing the Quality of Glucocorticoid Replacement [0.03%]
肾上腺皮质功能不全中FKBP5甲基化的研究：评估糖皮质激素替代治疗质量的新思路
Irina Chifu,Anna-Lena Richter,Juliane Lippert et al.
Irina Chifu et al.
Context: Methylation of FKBP5, a glucocorticoid(GC)-receptor co-chaperone, negatively correlates with cortisol levels in both healthy individuals and Cushing patients, potentially serving as an indicator of GC exposure. ...
Hannes Syryn,Elfride De Baere,Martine Cools
Hannes Syryn
Available pre- and postnatal tests for obtaining a molecular genetic diagnosis for differences of sexual development (DSD) have largely expanded over the last decade. More importantly, the medical management of these conditions has taken a ...